Just Published

PCC
Mania and Cerebral Amyloid Angiopathy
Case Report

image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ March 19, 2026

This report details a case in which a patient presented with mania in the setting of cerebral amyloid angiopathy and hypertension that did not abate until treatment with antihypertensives.
, , , et al
PCC
Atypical Presentation of Autoimmune Encephalitis
Case Report

March 19, 2026

A 23-year-old woman presented with probable antibody-negative autoimmune encephalitis that initially mimicked a primary psychiatric disorder.
, , , et al
PCC
Recreational Ketamine-Induced Uropathy
Brief Report

March 19, 2026

Two patients with chronic recreational ketamine use presented with urinary frequency, urgency, dysuria, and hematuria in the absence of infection.
, , , et al
JCP
Vitamin B12 Deficiency Risk With Metformin for Weight Management in Second-Generation Antipsychotic Recipients: Reply to Mulsant et al
Letter to the Editor

March 18, 2026

Daggolu and Chen reply to a letter commenting on their study of metformin use in patients receiving second-generation antipsychotics.
,
JCP
Concurrent Metformin and Second-Generation Antipsychotics: The Need to Add Vitamin B12
Letter to the Editor

March 18, 2026

The authors recommend vigilance for potential B12 deficiency when coprescribing metformin and antipsychotics.
, ,
JCP
Association of SSRIs and Other Antidepressants With Dental Implant Failure
Clinical and Practical Psychopharmacology

March 18, 2026

Antidepressant users should be educated about the risk of dental implant failure, and efforts should be made to identify and negate other risk factors for implant failure.

Explore
By Topic

View all topics
Addiction Anxiety Bipolar Disorder Depression (MDD) Movement Disorders Neurology Obsessive-Compulsive and Related Disorders Psychopharmacology Schizophrenia/Schizoaffective Disorders Tardive Dyskinesia

Original Research

JCP
Neuropsychiatric Symptom Clusters and Brain Structure in Alzheimer’s Disease
Original Research

March 16, 2026

Neuropsychiatric symptoms in Alzheimer’s disease separate into hyperactivity, psychosis, neurovegetative, and affective clusters, supporting a cluster-based paradigm linking behavioral symptoms with brain structure and functional decline.
, , , et al
JCP
Temporal Dynamics of Antidepressant Response Following Brexanolone Treatment in Postpartum Depression
Original Research

March 11, 2026

Temporal-Dynamics-Antidepressant-Response-Brexanolone-Treatment-Postpartum-Depression
, , , et al
PCC
Ultra–Low-Dose Mirtazapine for Chronic Insomnia
Original Research

March 10, 2026

In patients with insomnia disorder, a clinically relevant effect was seen with low-dose mirtazapine (3.75 mg) on insomnia severity from 1–3 months.
, , , et al

Recent Features

Figure: Woman in bed appears distressed, suggesting sleep difficulty; text highlights underrecognized sleep disorder in psychiatry.
Image shows a syringe below a question about schizophrenia relapse prevention; The Psychiatrist.com logo appears at the bottom.
Figure: Promotional graphic announces a consensus report on Xanomeline-Trospium use in practice, highlighting JCP branding.
Figure shows a hand holding a vial and syringe above report title on PK of aripiprazole LAIs as described in JCP.

The Journal of Clinical Psychiatry

The Journal of Clinical Psychiatry is a leader in peer-reviewed articles on mental health topics for psychiatrists and medical professionals. Now featuring The JCP Podcast: conversations with experts exploring the research shaping clinical care.  

EXPLORE JCP
JCP
Neural Dysconnectivity and Affective Disorders: Integrating Sleep and Emotional Regulation Perspectives
Letter to the Editor

March 16, 2026

The authors discuss sleep disturbance in the context of recent research on functional dysconnectivity in the brain’s triple networks.
, , , et al
JCP
Triple Network Dysconnectivity and Sleep Disturbance in Young People With Suicidal Ideation: Reply to Ferruzzi et al
Letter to the Editor

March 16, 2026

Cheng et al reply to a letter regarding their recent study of triple network functional dysconnectivity in major affective disorders.
, ,

Explore Special Sections from JCP

Focus on Childhood and Adolescent Mental Health Early Career Psychiatrists Focus on Geriatric Psychiatry Focus on Psychosis Focus on Psychotherapy Focus on Suicide Focus on Women’s Mental Health

The Primary Care Companion for CNS Disorders

The Primary Care Companion for CNS Disorders seeks to advance the clinical expertise of primary care physicians and other health care professionals who treat patients with mental and neurologic illnesses.

View PCC Articles
PCC
Tacrolimus-Induced Parasomnia Posttransplantation
Case Report

March 17, 2026

The authors present a rare case of tacrolimus-induced parasomnia, adding to the body of evidence on its neurotoxic potential.
, , , et al
PCC
Clozapine-Induced Antiphospholipid Syndrome
Case Report

March 12, 2026

A 68-year-old man with no pre‐existing risk factors experienced clozapine-induced antiphospholipid syndrome and a deep vein thrombosis.
, ,

ASCP - American Society of Clinical Psychopharmacology logo

Read articles from ASCP Corner

ASCP Corner

Consensus Report on XT Use in Practice

Read the full report
Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

Subscribe to read
more articles

Subscribe