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ECT for Psychosis in Huntington Disease-Like 2
Case Report

May 19, 2026

A 47-year-old woman with genetically confirmed Huntington disease-like 2 had refractory psychosis and functional decline but responded well to electroconvulsive therapy.
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PCC
Manifestations Associated With CNS Lesions
Rounds in the General Hospital

May 19, 2026

Neuropsychiatric manifestations of brain metastases are varied, although certain symptoms can be associated with the brain region in which there is a metastasis; lesions that affect certain parts of…
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JCP
Rethinking Postpartum Depression: Biology, Biomarkers, and New Treatments with Jennifer L. Payne, MD
Podcast

May 19, 2026

Jennifer L. Payne, MD, discusses postpartum depression biomarkers, allopregnanolone and GABA-A receptor biology, and the clinical profile of zuranolone.
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JCP
Systematic Review and Meta-Analysis of Use of Mood Stabilizers in Adolescents With Nonsuicidal Self-Injury
Meta-Analysis

May 18, 2026

Severity of anxiety, depression, impulsivity, and self-injury was significantly reduced following treatment with mood stabilizers.
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PCC
Peer Support to Prevent Suicide Among Medical Students
Letter to the Editor

May 14, 2026

The authors describe a peer support panel discussion designed to address suicide prevention, allowing medical students to actively participate in addressing critical mental health challenges they face in their…
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PCC
Adjunct Memantine for Inappropriate Sexual Behavior
Case Report

May 14, 2026

Two patients with intellectual disability and major neurocognitive disorder exhibited inappropriate sexual behavior that significantly decreased after memantine was added as adjunctive therapy.
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Original Research

JCP
NNT, NNH, and LLH for Aripiprazole Once-Monthly in Schizophrenia
Original Research

May 13, 2026

Data demonstrate a favorable benefit-risk profile for aripiprazole once-monthly 400 vs placebo in acute and maintenance treatment of schizophrenia.
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JCP
Efficacy and Safety of a Single Dose of Psilocybin for Chronic Suicidal Ideation
Original Research ▶ Video

May 13, 2026

A single psilocybin dose with psychological support was associated with rapid, large, and durable reductions in suicidal ideation and depressive symptoms.
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JCP
Effects of Experimental Intermittent Theta Burst Stimulation on Negative Symptoms of Schizophrenia
Original Research

May 11, 2026

Findings suggest limited efficacy of experimental intermittent theta burst stimulation over the left DLPFC for negative symptoms.
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The Journal of Clinical Psychiatry

The Journal of Clinical Psychiatry is a leader in peer-reviewed articles on mental health topics for psychiatrists and medical professionals. Now featuring The JCP Podcast: conversations with experts exploring the research shaping clinical care.  

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Catching Cognitive Decline Early with Gary W. Small, MD
Podcast

May 5, 2026

Dr. Gary W. Small on the continuum of age-related cognitive decline: biomarkers, differential diagnosis, treatment sequencing, and lifestyle interventions for brain health.
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JCP
CBT following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial
Original Research

May 4, 2026

In patients with major depression and suicidal ideation, adding a 16-week CBT course to esketamine led to greater improvements in suicidal ideation and depression severity than esketamine alone.
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The Primary Care Companion for CNS Disorders

The Primary Care Companion for CNS Disorders seeks to advance the clinical expertise of primary care physicians and other health care professionals who treat patients with mental and neurologic illnesses.

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PCC
From Physical to Digital: Hoarding Phenomena in Obsessive-Compulsive Disorder
Case Report

May 14, 2026

This case illustrates how hoarding phenomenology can manifest in digital environments, which offer virtually unlimited storage, anonymity, and low visibility.
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PCC
Differentiating Bipolar and Other Psychiatric Disorders
Rounds in the General Hospital

May 12, 2026

Diagnosis of bipolar spectrum disorder is often complicated, as most patients present for care during depressive episodes, which are more frequent than hypomanic or manic episodes.
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