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NNT, NNH, and LLH for Aripiprazole Once-Monthly in Schizophrenia
Original Research

May 13, 2026

Data demonstrate a favorable benefit-risk profile for aripiprazole once-monthly 400 vs placebo in acute and maintenance treatment of schizophrenia.
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JCP
Efficacy and Safety of a Single Dose of Psilocybin for Chronic Suicidal Ideation
Original Research ▶ Video

May 13, 2026

A single psilocybin dose with psychological support was associated with rapid, large, and durable reductions in suicidal ideation and depressive symptoms.
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PCC
Differentiating Bipolar and Other Psychiatric Disorders
Rounds in the General Hospital

May 12, 2026

Diagnosis of bipolar spectrum disorder is often complicated, as most patients present for care during depressive episodes, which are more frequent than hypomanic or manic episodes.
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PCC
Take “Oedipus” Off
Letter to the Editor

May 12, 2026

The authors examine justification for using the name of Oedipus to identify a psychoanalytic concept concerning children aged 3–6 years describing attraction to the parent of the opposite sex…
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JCP
Effects of Experimental Intermittent Theta Burst Stimulation on Negative Symptoms of Schizophrenia
Original Research

May 11, 2026

Findings suggest limited efficacy of experimental intermittent theta burst stimulation over the left DLPFC for negative symptoms.
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PCC
Aripiprazole-Induced Pathological Gambling
Case Report

May 7, 2026

A 27-year-old man with a history of substance abuse developed a new-onset compulsive gambling pattern within weeks of starting aripiprazole.
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Original Research

PCC
Readability of Self-Reported Psychosis Measures
Original Research

May 5, 2026

Most psychosis self-report measures are written above recommended reading levels, reducing accessibility for many patients with cognitive, educational, or symptomatic limitations.
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JCP
CBT following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial
Original Research

May 4, 2026

In patients with major depression and suicidal ideation, adding a 16-week CBT course to esketamine led to greater improvements in suicidal ideation and depression severity than esketamine alone.
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PCC
Antidepressant Monitoring Referrals to Higher-Level Services
Original Research

April 23, 2026

This study examined predictors of referral from a collaborative care model antidepressant monitoring program to higher levels of psychiatric services.
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The Journal of Clinical Psychiatry

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Catching Cognitive Decline Early with Gary W. Small, MD
Podcast

May 5, 2026

Dr. Gary W. Small on the continuum of age-related cognitive decline: biomarkers, differential diagnosis, treatment sequencing, and lifestyle interventions for brain health.
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JCP
Validation for the Tardive Dyskinesia Impact Scale, a Patient-Reported Outcome Measure in Valbenazine Clinical Trials
Narrative Review

April 29, 2026

The TDIS followed a similar trajectory to other clinician- and patient-reported outcomes measured in tardive dyskinesia clinical trials, and a change of 4 points in total score is considered…
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The Primary Care Companion for CNS Disorders

The Primary Care Companion for CNS Disorders seeks to advance the clinical expertise of primary care physicians and other health care professionals who treat patients with mental and neurologic illnesses.

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Strategies for Documenting the Medical Record
Rounds in the General Hospital

May 7, 2026

Documentation should be objective and relevant, especially in psychosocially complex cases—too much information can interfere with establishing the correct diagnosis and treatment plan, while too little increases risk of…
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PCC
Clozapine-Associated Pulmonary Embolism
Case Report

May 5, 2026

A 48-year-old woman with schizoaffective disorder taking clozapine developed acute pulmonary embolism despite negative D-dimer results.
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