The Journal of Clinical Psychiatry The Journal of Clinical Psychiatry

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Clinical Psychiatry

Empowering mental health professionals with peer-reviewed psychiatric research and insights

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JCP
Suvorexant and Lemborexant for Prevention of Delirium
Original Research

November 7, 2022

The novel dual orexin receptor antagonists (DORAs) suvorexant and lemborexant may be helpful in preventing delirium. This study examined the efficacy of these two DORAs in preventing delirium in…
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JCP
Relationship Between bvFTD and Psychiatric Disorders
Original Research

November 2, 2022

The behavioral variant of frontotemporal dementia (bvFTD) overlaps with primary psychiatric disorders (PPD). This study compared family history of PPD in patients with bvFTD, healthy controls, and patients with…
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JCP
Psychotropic Use in Youth With MDD and ADHD
Original Research

October 31, 2022

Data from a 17-year study point to overprescription of antipsychotics in school-aged children and indicate closer agreement between diagnosis and psychotropic use with age.
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JCP
Bipolar Disorder and PMDD: Comorbidity Conundrum
Commentary

October 26, 2022

Teri Pearlstein, MD, discusses a recent review that highlights the difficulties of diagnosing PMDD in women with bipolar disorder.
JCP
Relationship of PMDD and Bipolar Disorder
Systematic Review

October 26, 2022

In the 5 studies reviewed, 10%–15% of people with PMDD also had bipolar disorder, while 27%–76% of those with bipolar disorder also had PMDD.
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JCP
Combined Ketamine and Monoamine Oxidase Inhibitors
Systematic Review

October 24, 2022

Little is known about actual side effects of augmentation of ketamine to monoamine oxidase inhibitors (MAOIs). This systematic review and cases series evaluated symptoms of serotonin syndrome and hypertension…
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JCP
Overlapping Patterns of Suicide Attempts and Non-suicidal Self-Injuries in Adults
Original Research

image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ October 24, 2022

Among adults with self-injury behaviors, switching between episodes with and without suicidal intent is common and is associated with greater risk of suicidal behavior in the future.
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JCP
Impact of Major Depressive Disorder on Comorbidities
Systematic Review

October 19, 2022

Associations between major depressive disorder (MDD) and comorbid disorders have been studied, but not all have been explored systematically. This study summarized observational data on the effect of MDD…
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JCP
Relationship Between MDD and Medical Conditions
Commentary

October 19, 2022

This commentary by Rachel A. Weir, MD, and Mark Hyman Rapaport, MD, discusses the article by Alix M. Arnaud, MSc, and colleagues on the overlap between major depressive disorder…
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JCP
Acceptability of Second-Line Antidepressant Medications
Original Research

October 17, 2022

Second-line antidepressant options were ranked according to acceptability (efficacy and tolerability), using data from the French health system.
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JCP
Lost in Translation: The Value of Psychiatric Clinical Trials
Commentary

October 17, 2022

John C. Markowitz, MD, and Barbara L. Milrod, MD, assert the value of clinical trials in psychiatry and outline reasons why NIMH should resume supporting them.
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JCP
Living in a Pharmacologically Imperfect World
Editorial

October 12, 2022

Joseph F. Goldberg, MD, comments on prescription of valproate in women of reproductive potential, and the risk-benefit analysis involved with choosing the least imperfect treatment option.

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