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More JCP Articles
Commentary
Discontinuing Antidepressants: How Can Clinicians Guide Patients and Drive Research?
November 26, 2019
This commentary discusses common decisional uncertainties surrounding antidepressant discontinuation syndrome in the clinical setting and seeks to outline a roadmap for clinicians to drive research on this important topic.
Clinical and Practical Psychopharmacology
Gestational Exposure to Benzodiazepines, Part 3
November 26, 2019
Clobazam is widely used for seizure disorders and anxiety, but its potential teratogenicity has been little discussed in the literature. In this article, Dr Andrade reviews the evidence regarding…
Original Research
Kidney Function and Serum Risperidone Concentrations
November 26, 2019
Risperidone is mainly metabolized hepatically to its metabolite 9-hydroxyrisperidone (9-OH-RIS), which is excreted renally. This study examined how kidney function affects serum concentrations of risperidone and 9-OH-RIS in a…
Letter to the Editor
BMI and Remission in Depressed Patients Receiving IV Ketamine
November 12, 2019
Few studies have evaluated optimal dosing of intravenous (IV) ketamine for treatment-resistant depression (TRD). This report analyzes data from previous studies of IV ketamine to assess the association between…
Original Research
Brain Imaging in Adolescents With First-Episode Psychosis
November 5, 2019
Does neuroimaging, particularly computed tomography and magnetic resonance imaging, have diagnostic value in young patients with first-episode psychosis? Read the results of this retrospective cohort study to learn more.
Original Research
Physician-Assisted Suicide in Psychiatry
November 5, 2019
Although euthanasia and physician-assisted suicide (EAS) are permitted in the Netherlands under certain conditions, Dutch psychiatrists are increasingly reluctant to consider it. This article explores Dutch psychiatrists’ reasons for…
Original Research
Utility of Combinatorial Pharmacogenomics in Depression
October 31, 2019
This study sought to ascertain the extent that pharmacogenetic testing can inform treatment decisions among patients with treatment-resistant depression whose medications are subject to gene-drug interactions—read the article to…
Original Research
EEG Characteristics of Suicidal Behavior in Female Patients With MDD
October 29, 2019
Could biomarkers help predict acute suicide risk? This EEG study investigated whether MDD patients with suicidal attempts or ideation have unique spatial-frequency power characteristics versus MDD patients without suicidal…