Case Report

PCC
Bupropion-Dextromethorphan for Clinically Challenging Apathy
Case Report

April 2, 2026

This case shows potential benefits of glutamate system–activating medication in addressing clinically challenging apathy in a 44-year-old man with depression.
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PCC
A Unique Manifestation of Postpartum OCD
Case Report

March 31, 2026

This report explores the case of a woman with postpartum OCD, who exhibited a unique compulsion of taking excessive photos and videos of her surroundings.
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PCC
Mesial Temporal Sclerosis and Juvenile Myoclonic Epilepsy
Case Report

March 26, 2026

The authors present a rare case of coexisting right mesial temporal sclerosis and juvenile myoclonic epilepsy, underscoring the challenges in dual epilepsy syndromes and the importance of individualized, multidisciplinary...
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PCC
Between Crisis and Clarity: Steroid-Induced Psychosis in Addison Disease
Case Report

March 24, 2026

This case highlights a rare but clinically significant dilemma: balancing essential corticosteroid replacement against neuropsychiatric toxicity.
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PCC
Mania and Cerebral Amyloid Angiopathy
Case Report

March 19, 2026

This report details a case in which a patient presented with mania in the setting of cerebral amyloid angiopathy and hypertension that did not abate until treatment with antihypertensives.
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PCC
Atypical Presentation of Autoimmune Encephalitis
Case Report

March 19, 2026

A 23-year-old woman presented with probable antibody-negative autoimmune encephalitis that initially mimicked a primary psychiatric disorder.
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PCC
Tacrolimus-Induced Parasomnia Posttransplantation
Case Report

March 17, 2026

The authors present a rare case of tacrolimus-induced parasomnia, adding to the body of evidence on its neurotoxic potential.
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PCC
Clozapine-Induced Antiphospholipid Syndrome
Case Report

March 12, 2026

A 68-year-old man with no pre‐existing risk factors experienced clozapine-induced antiphospholipid syndrome and a deep vein thrombosis.
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PCC
Caffeine for ICI Encephalitis
Case Report

March 5, 2026

With the increased use of immune checkpoint inhibitors, the potential for aseptic encephalitis poses a unique challenge to patient rehabilitation.
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PCC
Misophonia With Psychiatric Comorbidities
Case Report

March 3, 2026

This case highlights the need for enhanced recognition of misophonia, integrated care pathways, and improved mental health infrastructure in low- and middle-income countries.
PCC
Intranasal Tapentadol Dependence
Case Report

February 26, 2026

The authors present 2 cases of intranasal tapentadol dependence marked by rapid tolerance and significant physical and psychological issues.
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JCP
Oral Glutamatergic Modulation with Dextromethorphan and Piracetam for Refractory Bipolar Disorder With OCD
Case Report

February 23, 2026

Three patients with combined bipolar disorder and OCD experienced remission of depressive, anxious, and obsessive-compulsive symptoms after piracetam was added to dextromethorphan.
PCC
Calcineurin Inhibitor–Induced Psychosis
Case Report

February 17, 2026

The authors report a case of delayed and recurrent calcineurin inhibitor–induced psychosis with both tacrolimus and cyclosporine, highlighting the need to better understand host vulnerability and risk stratification.
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PCC
Arm EMG and Detection of REM Sleep Without Atonia
Case Report

February 17, 2026

This case highlights the importance of utilizing arm EMG to accurately detect REM sleep without atonia, as REM sleep behavior disorder often precedes the development of α-synucleinopathies, such as...
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PCC
Long-Term High-Intensity Drinking
Case Report

February 12, 2026

This case underscores the need to recognize episodic high-intensity alcohol use as a clinically relevant presentation that carries medical and social risks despite the absence of daily drinking.
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PCC
Periodic Catatonia in an Adult With Autism
Case Report

February 3, 2026

The authors report a case of periodic catatonia in a 30-year-old man with autism spectrum disorder, with no other identifiable psychiatric or neurological comorbidities, that responded to lithium prophylaxis.
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PCC
When the Labs Don’t Add Up: Factitious Disorder and Successful Treatment
Case Report

January 27, 2026

This case of a 37-year-old woman, who presented to the ED with recurrent syncope and acute kidney injury, demonstrates successful long-term treatment of factitious disorder, highlighting the complexities of...
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PCC
High-dose Veterinary AMP Dependence
Case Report

January 27, 2026

A 41-year-old man self-administered mega-doses of veterinary adenosine monophosphate over an extended period and experienced intense withdrawal and psychological symptoms after discontinuation.
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PCC
Basal Ganglia Stroke With Lower Motor Neuron Features
Case Report

January 22, 2026

A 60-year-old man exhibited left-sided toe walking and right-sided weakness despite previous history of left sided basal ganglia stroke, challenging the notion that adult toe walking is a hallmark...
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PCC
Benign Ethnic Neutropenia and Clozapine
Case Report

January 22, 2026

This case highlights the importance of recognizing benign ethnic neutropenia to prevent unnecessary clozapine discontinuation.
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PCC
Depression Remission in Parkinson Disease With iTBS
Case Report

January 20, 2026

Two cases demonstrate the potential for intermittent theta burst transcranial magnetic stimulation to rapidly reverse treatment-resistant depression in patients with Parkinson disease.
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PCC
Lithium-Induced Rash: Unveiling the Dermatological Dilemma
Case Report

January 20, 2026

A 32-year-old woman recently diagnosed with bipolar affective disorder developed lithium-induced rash that did not recur on rechallenge.
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PCC
Skin Picking in Profound Intellectual Disability
Case Report

January 15, 2026

A 39-year-old woman with profound intellectual disability and delayed developmental milestones presented with late-onset severe dermatillomania.
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PCC
LSD-Induced Catatonia in an Adolescent
Case Report

January 13, 2026

A 16-year-old boy experienced catatonia associated with lysergic acid diethylamide use.
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Consensus Report on XT Use in Practice

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Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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