Meta-Analysis

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JCP
Meta-Analysis

May 26, 2020

The FDA has now approved intranasal esketamine as augmention in treatment-resistant depression, and recent studies of its efficacy have been encouraging. This meta-analysis synthesizes the evidence to provide an...
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JCP
Meta-Analysis

May 19, 2020

The most effective treatment for reducing transition to psychosis among youth at clinical high risk for psychosis has not been determined. The present systematic review and meta-analyses summarize all...
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JCP
Meta-Analysis

March 24, 2020

For ADHD patients who responded to medication treatments, does discontinuing those medications affect quality of life more adversely than continuing them? This study compares the effects of continuing versus...
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JCP
Meta-Analysis

March 10, 2020

Some women experience severe affective episodes outside the postpartum period after an initial episode of postpartum psychosis, though others do not. This meta-analysis estimates the risk of recurrence after...
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JCP
Meta-Analysis

February 25, 2020

Varenicline reduces smoking. Since alcohol use and tobacco use disorders are often comorbid, does the effectiveness of varenicline in reducing tobacco use translate to a similar effectiveness for alcohol-related...
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JCP
Meta-Analysis

January 21, 2020

Evidence for an effect of exercise on depression in older adults is scant and heterogeneous. This meta-analysis included trials with a specific exercise dose and assessed sources of heterogeneity—read...
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PCC
Meta-Analysis

December 19, 2019

Patients with severe mental illness tend to have a higher prevalence of metabolic disorders. This review updates the current evidence on the effectiveness of add-on medications to treat weight...
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PCC
Meta-Analysis

August 22, 2019

While benzodiazepines are considered the standard of care for alcohol withdrawal, gabapentin is a valuable alternative that can also help with cravings and abstinence long term. Read on to...
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JCP
Meta-Analysis

July 23, 2019

Addressing anxiety disorders in pregnant women and new mothers is important, especially given the potential effects on offspring. Do you know which disorders are most common? Read this meta-analysis...
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JCP
Meta-Analysis

July 9, 2019

Is prenatal benzodiazepine use associated with an increased risk of congenital malformations? What about concurrent use of a benzodiazepine and an antidepressant? Does the trimester have an effect? See...
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JCP
Meta-Analysis

April 30, 2019

Methylphenidate is related to sleep-related adverse events. This meta-analysis sought to quantify this impact of methylphenidate and determine the varieties of sleep problems associated with this drug.
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JCP
Meta-Analysis

April 2, 2019

The prevalence of pediatric bipolar disorder is an ongoing topic of debate, and the body of research has grown in recent years. Read this article to learn about current...
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JCP
Meta-Analysis

March 19, 2019

Computer-assisted cognitive-behavior therapy (CCBT) allows clinicians to deliver evidence-based care to more patients than would be possible with standard CBT. This meta-analysis sought to determine if additional clinician support...
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JCP
Meta-Analysis

January 29, 2019

Given the limited efficacy and questionable safety profiles of current pharmacologic treatments of agitation in Alzheimer's disease (AD), the therapeutic potential of natural and synthetic cannabinoids are being explored...
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JCP
Meta-Analysis

January 22, 2019

eHealth interventions are effective for the treatment of anxiety in the general population, though results of individual studies of perinatal anxiety have been mixed. Given the high prevalence of anxiety...
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JCP
Meta-Analysis

September 18, 2018

Tardive dyskinesia, a side effect of antipsychotics, is a persistent and disabling problem among patients with schizophrenia. Could a switch to clozapine help? This meta-analysis looks at 16 studies...
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JCP
Meta-Analysis

September 4, 2018

Anxiety is common during pregnancy, but reviews to date of the impact of anxiety on perinatal outcomes have been narrow in focus. This systematic review and meta-analysis synthesizes available...
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JCP
Meta-Analysis

July 31, 2018

Read a meta-analysis explores the prevalence of MDD in all causes of dementia and diagnostic criteria when finding these disorders.
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JCP
Meta-Analysis

June 5, 2018

Internet addiction has been associated with other psychiatric disorders and with higher rates of suicidality. This meta-analysis looks at the risk of suicidality, factors that could modify the risk...
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JCP
Meta-Analysis

May 15, 2018

If an antidepressant doesn' t seem to be working, what is your next move? This meta-analysis compares efficacy and tolerability of increasing antidepressant dose versus continuing the initial dose....
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JCP
Meta-Analysis

April 3, 2018

After you start patients on antidepressant therapy, how long should it take for them to respond? This meta-analysis looks at existing data to estimate the probability of additional response...
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JCP
Meta-Analysis

March 6, 2018

Case reports suggest psychosis might worsen with a switch to or addition of aripiprazole. But is worsening just as likely with other antipsychotics? To answer this question, this government-supported...
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JCP
Meta-Analysis

November 28, 2017

Read an article to see if bipolar prevalence has changed over time or varies among the world regions according to 85 epidemiologic studies representing 44 countries.
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JCP
Meta-Analysis

September 19, 2017

Acute sleep deprivation is one of the most rapid antidepressant interventions known; however, its benefits are usually short-lived. This meta-analysis synthesizes the existing data on acute sleep deprivation in...
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