Original Research
Original Research
Incidence and Risk Factors for Suicide Attempt During Pregnancy and Postpartum
March 5, 2025
Risks of a postpartum suicide attempt were increased 4- to 30-fold by clinical factors, including prenatal suicide attempt ED visits, psychiatric ED visits, and assault ED visits, and by...
Original Research
Safety and Tolerability of Xanomeline and Trospium Chloride in Schizophrenia: Pooled Results From the EMERGENT Trials
February 26, 2025
In pooled analyses, xanomeline/trospium was generally well tolerated. The most common adverse events were mild or moderate, transient, and consistent with the activity of xanomeline and trospium at muscarinic...
Original Research
Brexpiprazole in Combination with Sertraline and as Monotherapy in PTSD: A Full-Factorial Randomized Clinical Trial
February 19, 2025
In this 10-week study, brexpiprazole in combination with sertraline, but not as monotherapy, demonstrated the potential to be a new efficacious treatment for PTSD.
Original Research
Sequencing Stimulants and Behavioral Parent Training in Multiplex ADHD Families
February 19, 2025
Combination treatment may be helpful for most multiplex ADHD families, and sequencing treatments with behavioral parent training first followed by stimulant medication for the mother may be the most...
Original Research
Medical Education and the COVID-19 Pandemic
February 11, 2025
The pandemic disrupted traditional undergraduate medical education and required adaptations to the clerkship curriculum, such as integration of virtual patient care and telehealth services, to provide meaningful learning experiences.
Original Research
Esketamine Nasal Spray vs Quetiapine ER in Treatment-Resistant Depression
January 27, 2025
Esketamine was associated with significantly larger improvements in work productivity loss and related costs compared to quetiapine, suggesting greater benefits from patient well-being and employer perspectives.
