Original Research
Original Research
Defense Mechanisms and Common Psychiatric Disorders
April 28, 2025
Individuals with mood, anxiety, or substance use disorders generally had a higher prevalence of defense mechanisms than those with no disorders. Defense mechanisms and psychiatric disorders represent correlated but...
Original Research
One-Day Online CBT-Based Workshops for the Prevention of Postpartum Depression
April 16, 2025
Reductions in Edinburgh Postnatal Depression Scale (EPDS) scores were seen in the CBT group at 2 months but were not statistically significant. Higher risk participants with a baseline EPDS...
Original Research
Appetite Hormone Regulation Biotypes of Major Affective Disorders
April 9, 2025
Three appetite hormone regulation biotypes were identified among patients with major affective disorders. They were associated with proinflammatory cytokine profiles and executive function, with one biotype group showing poorer...
Original Research
Older Adults Visiting Emergency Departments for Mental Health Issues:A CHIRPP Database Study
April 2, 2025
Suicidal ideations and neurocognitive disorders were the most frequent diagnostic impressions, with males at higher risk of neurocognitive and substance use disorders. Patients 85 or older were more likely...
Original Research
Association of Pregnancy-Related Anxiety With Perceived Social Support: An Observational Study Among Third-Trimester Antenatal Women
March 20, 2025
Late-pregnancy anxiety was linked to perceived social support, and specific pregnancy-related anxiety themes, such as concerns about giving birth, the child’s health, one’s own appearance, correlated with distinct perceived...
Original Research
Negative Ethnic-Racial Identity and Internalizing Symptoms in Latiné Youth Exposed to Trauma
March 17, 2025
In a large group of Latiné youth who had experienced trauma, negative affect about their ethnic racial identity not only was associated with worse internalizing symptoms, but also increased...
Original Research
Suicide and Benzodiazepine Use in Veterans With Bipolar Disorder
March 12, 2025
Among VHA patients diagnosed with bipolar disorder, receipt of a benzodiazepine prescription of ≥ 30 days was associated with increased suicide risk, even after controlling for clinical and demographic...
Original Research
Incidence and Risk Factors for Suicide Attempt During Pregnancy and Postpartum
March 5, 2025
Risks of a postpartum suicide attempt were increased 4- to 30-fold by clinical factors, including prenatal suicide attempt ED visits, psychiatric ED visits, and assault ED visits, and by...
Original Research
Safety and Tolerability of Xanomeline and Trospium Chloride in Schizophrenia: Pooled Results From the EMERGENT Trials
February 26, 2025
In pooled analyses, xanomeline/trospium was generally well tolerated. The most common adverse events were mild or moderate, transient, and consistent with the activity of xanomeline and trospium at muscarinic...
Original Research
Brexpiprazole in Combination with Sertraline and as Monotherapy in PTSD: A Full-Factorial Randomized Clinical Trial
February 19, 2025
In this 10-week study, brexpiprazole in combination with sertraline, but not as monotherapy, demonstrated the potential to be a new efficacious treatment for PTSD.
Original Research
Sequencing Stimulants and Behavioral Parent Training in Multiplex ADHD Families
February 19, 2025
Combination treatment may be helpful for most multiplex ADHD families, and sequencing treatments with behavioral parent training first followed by stimulant medication for the mother may be the most...
