Original Research

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JCP
Toward A Definition Of “No Meaningful Benefit” From Antidepressant Treatment
Original Research

June 27, 2022

The aim of this study was to develop and validate a categorical definition of “no meaningful benefit” from antidepressant treatment by equating percent change in scores on 3 common...
, , , et al
JCP
Nocturnal Wakefulness and Suicide
Original Research

June 22, 2022

Research examining time-of-day as a potential suicide risk factor has produced mixed results. This study analyzed the time-of-day for suicide cases from the Australian population during an entire calendar...
, , , et al
JCP
Association of Bupropion and Opioid Use Disorder Medications With Stimulant-Related Admissions
Original Research

June 20, 2022

This study investigated whether bupropion and OUD medications (buprenorphine, naltrexone, and methadone) are associated with decreased stimulant-related ED admissions and hospitalizations in people with OUD who had at least...
, , , et al
PCC
Social Anxiety Among Lebanese Adolescents
Original Research

June 16, 2022

The objective of this cross-sectional study was to determine the prevalence of social anxiety among Lebanese adolescents and assess its association with bullying and child abuse.
, , , et al
JCP
Mental Pain, Suicide Risk, and Childhood Trauma
Original Research

June 15, 2022

This study investigated if mental pain was associated with recent suicide attempt and whether it could mediate the relationship between childhood trauma and suicide risk.
, , , et al
JCP
Maternal Postnatal Depression and Infant Immunizations
Original Research

June 13, 2022

The relationship between maternal postnatal depression and infant vaccination is uncertain. This study examined whether infants of mothers who sought support for postnatal depression were less likely to receive...
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JCP
Predictors of Suicidality After Psychiatric Hospitalization
Original Research

June 13, 2022

This study examined the incidence and predictors of suicide attempts and deaths in the year after psychiatric hospitalization; covariates included sex, geographic location, and physical health conditions.
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PCC
Vortioxetine Supratherapeutic Dosing in TRD
Original Research

June 9, 2022

This study evaluated the effectiveness and tolerability of vortioxetine at supratherapeutic dosages in patients with treatment-resistant depression.
, , , et al
JCP
Pregnancy Outcomes With First-Trimester SGA Exposure
Original Research

June 8, 2022

In Japan, information regarding the effects of antipsychotics on the fetus during pregnancy is limited. This Japanese study examined the association between the use of antipsychotics during pregnancy and...
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PCC
Cholesterol, Obesity, and Metabolic Syndrome in Epileptic Patients
Original Research

June 7, 2022

This study compared cardiovascular risk factors in patients with epilepsy with those of non-epileptic neurologic patients to determine their association with antiepileptic drug therapy.
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JCP
Transdermal HP-3070 for Hostility in Schizophrenia
Original Research

June 6, 2022

Schizophrenia is sometimes accompanied by aggressive, hostile behavior, particularly during the acute phase. This post hoc analysis of a phase 3 study examines the efficacy of transdermal asenapine (HP-3070)...
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JCP
Suicide Risk in a National VA Sample
Original Research

June 6, 2022

Predicting suicide is difficult, as suicidal behavior is not linked solely to any single behavior or psychiatric diagnosis. This study compared risk of suicidal behavior among a transdiagnostic sample...
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JCP
Long-term Outcomes of Early Use of LAIs in Schizophrenia
Original Research

June 1, 2022

Using data from the Taiwan National Health Insurance Research Database, the authors compared long-term effectiveness of switching to long-acting injectable antipsychotics versus remaining on oral antipsychotics.
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PCC
Sleep in Older Adults During the COVID-19 Pandemic
Original Research

May 31, 2022

This study measured the impact of the COVID-19 pandemic on sleep and how it correlates with the feeling of isolation in individuals aged 50 years and older.
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JCP
Efficacy and Safety of AXS-05 (Dextromethorphan-Bupropion) in MDD
Original Research

May 30, 2022

Altered glutamatergic neurotransmission has been implicated in the pathogenesis of depression. This phase 3 trial evaluated the efficacy and safety of AXS-05 (dextromethorphan-bupropion) in the treatment of major depressive...
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PCC
COVID Vaccination Among Patients With Severe Mental Illness
Original Research

May 26, 2022

This study explored COVID-19 vaccination status among community-dwelling patients with severe mental illness and identified associated factors.
PCC
Attachment Styles and Mental Health in Adolescents
Original Research

May 19, 2022

This study assessed the association between insecure attachment styles and depression, social anxiety, and suicidal ideation among Lebanese adolescents.
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JCP
Clozapine Use in Singapore and Hong Kong
Original Research

May 18, 2022

This survey investigated clinicians’ use of clozapine for schizophrenia, beliefs about its effectiveness, and concerns regarding this medication.
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JCP
Youth Aware of Mental Health (YAM) Intervention
Original Research

May 16, 2022

Youth Aware of Mental Health (YAM) is a manualized universal intervention designed to increase mental health awareness about protective factors, depression and suicide, and coping skills. This study assessed...
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JCP
Eating Disorders in Youth With Bipolar Disorder
Original Research

May 11, 2022

Research has shown the importance of comorbid eating disorders (ED) in bipolar disorder (BD), though most studies have focused on adults. This study examined the prevalence and correlates of...
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JCP
Antipsychotic Efficacy of KarXT (Xanomeline−Trospium)
Original Research

image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ May 11, 2022

This post hoc analysis of phase 2 data evaluated rates and time course of response with the new combination oral agent KarXT (xanomeline−trospium) in the treatment of schizophrenia.
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PCC
Social and Emotional Health of College Students and COVID-19
Original Research

May 10, 2022

This study assessed the social and emotional health of university students in India as influenced by COVID-19 test results and the experience of isolation or quarantine.
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JCP
Daily Dose Effects of Risperidone on Metabolic Parameters
Original Research

May 9, 2022

This study investigated whether dose is a factor in the development of metabolic side effects with atypical antipsychotics.
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PCC
Resilience, Coping, Distress, and COVID-19
Original Research

May 5, 2022

The authors of this study assessed psychological resilience, coping, and related psychological distress in COVID-19 patients admitted to the hospital.
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