Original Research
Original Research
Efficacy of Citalopram Treatment in Bipolar Depression
January 12, 2021
Antidepressants are widely used to treat bipolar illness, though their effectiveness in this disorder has not been established. This randomized, double-blind, placebo-controlled trial assessed the efficacy and safety of...
Original Research
Factors Related to Suicide Mortality in Young Adults
December 29, 2020
Sociodemographic factors, health behaviors, and biological indicators as risks for suicide are relatively understudied among young adults. This study sought to determine which nonpsychiatric factors might be associated with...
Original Research
Outcomes and Treatment Response in Schizophrenia
December 23, 2020
To better understand the burden of partial treatment response on schizophrenia patients, their caregivers, and health care resources, this study compared demographics, outcomes, and comorbidities among schizophrenia patients with...
Original Research
Sleep and Seclusion and Restraint in Pediatric Inpatients
December 23, 2020
This study examined characteristics of pediatric psychiatric inpatients who experienced seclusion and restraint events and assessed if sleep time before and after the event was different from average sleep...
Original Research
Asenapine Transdermal System for Schizophrenia
December 15, 2020
Transdermal asenapine administration may address unmet needs in patients with schizophrenia, including improved adherence. This phase 3 study assessed efficacy and safety of HP-3070, an asenapine transdermal system (patch),...
Original Research
Predictors of ECT Treatment Response in Depression
December 15, 2020
Several clinical variables assumed to predict electroconvulsive therapy (ECT) outcome in major depressive disorder are interrelated. This study tries to disentangle this interdependence to distill the most important predictors...
Original Research
Socioeconomic Risk Factors for Medication Nonadherence
December 10, 2020
Nonadherence to psychiatric treatment is associated with poor outcomes. This study investigated the association of socioeconomic factors, race/ethnicity, and patient perceptions with medication adherence in individuals with depression.
Original Research
Antipsychotics for Homeless and Unstably Housed Veterans
December 8, 2020
Many homeless and unstably housed (HUH) adults have severe mental illness managed with antipsychotic medications. This study examined antipsychotic medication use and correlates of antipsychotic medication prescriptions among HUH...
Original Research
Adjunctive Pimavanserin and Sleep/Wakefulness in MDD
December 1, 2020
Adjunctive pimavanserin can reduce depressive symptoms and improve function in patients with major depression and inadequate antidepressant response. This analysis evaluated the effects of adjunctive pimavanserin on sleep/wakefulness disturbances.
Original Research
Depression Literacy Among Dermatologists
November 19, 2020
Increased depression literacy among dermatologists might play a vital role in early and successful detection and treatment of depression among their patients. This study investigated depression literacy among dermatologists...
Original Research
Association Between GlycA and Depressive Symptoms
November 17, 2020
Since the association of the inflammatory biomarker hs-CRP with depression is unclear, alternative inflammatory biomarkers of depression are needed. This study examined the association between the inflammatory biomarker GlycA...
Original Research
Routine Screening for Autoimmune Encephalitis
November 17, 2020
Autoimmune encephalitis (AE) is a highly treatable neurologic condition that can cause psychosis. This study estimated the cost-effectiveness of routine screening for AE compared with clinically targeted screening in...
Original Research
Happiness During Low-Dose Ketamine Infusion Predicts Treatment Response
November 10, 2020
Can we determine which patients will respond to ketamine just by observing their mood during the infusion? This study evaluated antidepressant outcomes with ketamine in 71 patients, focusing on ...
Original Research
COVID-19 Transmission in a Psychiatric Facility
November 5, 2020
This study reports the clinical characteristics and transmission rate of COVID-19 in an inpatient long-term care psychiatric facility to provide insight into transmission and symptom patterns, testing protocols, medical...
Original Research
Riluzole for Antidepressant-Resistant PTSD
October 27, 2020
Current pharmacologic treatments for posttraumatic stress disorder (PTSD) have shown limited efficacy. This study investigated the efficacy of the glutamatergic modulator riluzole for combat-related PTSD symptoms resistant to SSRIs...
