Original Research
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Original Research
Reminder-Focused Positive Psychiatry in ADHD and PTSD
September 3, 2020
Research has revealed the feasibility of positive psychiatry in youth. This study investigated the impact of reminder-focused positive psychiatry on PTSD and ADHD symptoms, neuroinflammation, vascular function, well-being, and...
Original Research
Long-Term Antidepressant Treatment and Risk of Dementia
August 25, 2020
The effects of antidepressants and treatment duration on the progression to dementia are currently unclear. This case-control study analyzed the effects of several antidepressants with different treatment durations on...
Original Research
Long-Term Safety of Aripiprazole Lauroxil
August 18, 2020
Long-acting injectable (LAI) antipsychotics improve adherence, reduce treatment gaps, and improve clinical outcomes. This report describes the long-term safety, tolerability, and symptom trajectory with the LAI antipsychotic aripiprazole lauroxil.
Original Research
INP105 (Nasal Olanzapine) in Healthy Adults
June 30, 2020
Aside from intramuscular injection, few rapidly acting pharmacotherapeutic treatments are available for acute agitation. This study examined the safety and tolerability of INP105, a drug-device combination product that allows...
Original Research
Ganaxolone for Persistent Depression
June 9, 2020
Postmenopausal women may be deficient in the neuroactive steroid allopregnanolone. This study examined oral ganaxolone, an allopregnanolone analog, as augmentation therapy in postmenopausal women with inadequate response to traditional...
Original Research
Benzodiazepines, Antidepressants, and Antipsychotics and Mortality in Patients With Dementia
June 2, 2020
Patients with dementia often receive antipsychotics in combination with other psychotropic medications. This study compared mortality for antipsychotics combined with benzodiazepines or antidepressants with that for antipsychotic monotherapy.