Original Research
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Original Research
Kidney Function and Serum Risperidone Concentrations
November 26, 2019
Risperidone is mainly metabolized hepatically to its metabolite 9-hydroxyrisperidone (9-OH-RIS), which is excreted renally. This study examined how kidney function affects serum concentrations of risperidone and 9-OH-RIS in a...
Original Research
Brain Imaging in Adolescents With First-Episode Psychosis
November 5, 2019
Does neuroimaging, particularly computed tomography and magnetic resonance imaging, have diagnostic value in young patients with first-episode psychosis? Read the results of this retrospective cohort study to learn more.
Original Research
Physician-Assisted Suicide in Psychiatry
November 5, 2019
Although euthanasia and physician-assisted suicide (EAS) are permitted in the Netherlands under certain conditions, Dutch psychiatrists are increasingly reluctant to consider it. This article explores Dutch psychiatrists' reasons for...
Original Research
Utility of Combinatorial Pharmacogenomics in Depression
October 31, 2019
This study sought to ascertain the extent that pharmacogenetic testing can inform treatment decisions among patients with treatment-resistant depression whose medications are subject to gene-drug interactions—read the article to...
Original Research
EEG Characteristics of Suicidal Behavior in Female Patients With MDD
October 29, 2019
Could biomarkers help predict acute suicide risk? This EEG study investigated whether MDD patients with suicidal attempts or ideation have unique spatial-frequency power characteristics versus MDD patients without suicidal...
Original Research
Posttraumatic Stress and Binge Eating
October 22, 2019
Trauma-exposed individuals engage in health-risk behaviors, though one such behavior—binge eating—is understudied in this population. This study evaluates the association between trauma exposure, posttraumatic stress disorder symptoms, and binge...
Original Research
Metabolic Syndrome in Treatment-Resistant Depression
October 15, 2019
This study aimed to estimate the prevalence of metabolic syndrome and its components in patients with treatment-resistant depression and determine correlations with sociodemographic, clinical, and treatment-related factors—read the article...
Original Research
Sex Differences in Depressive Symptoms in Schizophrenia
October 15, 2019
Sex-specific differences occur in several aspects of schizophrenia, though sex differences in comorbid depressive symptoms have not specifically been reported. This study examined sex differences in depressive symptoms in...
Original Research
Serum Folate and Vitamin B12 in Psychiatric Inpatients
October 10, 2019
Vitamin B12 deficiency is associated with various psychiatric symptoms. This study assessed the pattern of serum folate and vitamin B12 levels in psychiatric inpatients compared to nonpsychiatric controls in...
Original Research
Brexpiprazole in MDD—Metabolic Parameters and Weight
October 1, 2019
Adjunctive atypical antipsychotics can increase antidepressant response in depressed patients, but may cause adverse metabolic effects. This study examines the metabolic effects of adjunctive brexpiprazole in patients with major...
Original Research
Self-Compassion Intervention for Medical Patients
September 26, 2019
Self-compassion-based interventions train people to be kind to themselves during life's difficulties. This article examines the feasibility of a 4-session intervention for midlife and older adults with chronic medical...
