Original Research
Original Research
Sudden Improvement in Symptoms During Antidepressant Clinical Trials
December 4, 2018
If a patient's depressive symptoms subside very quickly after antidepressant treatment is initiated, do those gains represent a true and lasting response? This study examined whether sudden improvement in...
Original Research
Depression, Cognition, and Functional Impairment
November 13, 2018
Depression is strongly associated with functional impairment. Some hypothesize that cognitive dysfunction, which is also often associated with depression, might mediate the impact of depression on functioning. This study...
Original Research
Impact of Frailty on Behavioral and Psychological Symptoms of Dementia and Caregiver Burden
November 13, 2018
Frailty is associated with negative health outcomes in dementia patients, but could it also predict more psychological symptoms and greater caregiver burden? This study of 1,193 Alzheimer's disease patients...
Original Research
Cerebral Blood Flow After Late-Life Depression Treatment
October 23, 2018
Could cerebrovascular disease be a factor in your elderly patient's depression? This article investigated the association of white matter hyperintensities and cerebral blood flow with late-life depressive symptoms and...
Original Research
Customized Adherence Enhancement for Bipolar Disorder
September 25, 2018
Treatment nonadherence is bipolar disorder ranges from 20% to 60%. Read this article to learn how customized adherence enhancement (CAE)—a brief, bipolar disorder-specific approach that targets individual adherence barriers—compared...
Original Research
Developmental Trauma Disorder: Advancing Toward an Empirically Based Diagnosis
September 11, 2018
Children who have experienced victimization such as maltreatment or violence are at risk for problems that include, but extend beyond, PTSD. To guide assessment and treatment of these youth,...