Original Research

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JCP
Original Research

January 25, 2017

If clinical trials by design exclude as many as 85% of individuals with a target disorder, how can these studies be representative of the clinical population? Discover in this...
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JCP
Original Research

January 25, 2017

It's well known that people with chronic mental disorders are at greater risk of cardiovascular disease and other physical health conditions. Could a collaborative care model improve physical health-related...
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JCP
Original Research

January 25, 2017

Read a placebo-controlled study discussing OROS methylphenidate dosages in treatment for Adult Attention-Deficit/Hyperactivity Disorder (ADHD).
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JCP
Original Research

January 25, 2017

Want to improve your strategy for treating older depressed patients with metabolic syndrome?  Read this article to see how particular cardiovascular risk factors contribute to a chronic course.
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JCP
Original Research

January 25, 2017

Environmental and genetic risk factors influence whether a person will develop depression as well as what the prognosis will be. This study looked at illness incidence over 10 years...
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JCP
Original Research

January 25, 2017

Can physical fitness determine your patients' odds of developing some psychiatric disorders? This large population-based study with a median follow-up of 4.5 years looked at the relationships of both...
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JCP
Original Research

January 25, 2017

Many studies have shown that people with MDD have reduced work productivity, and cognitive symptoms are common. This study looked at whether antidepressant treatment with vortioxetine would improve cognitive...
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JCP
Original Research

January 17, 2017

The shorter life expectancy in patients with psychotic disorders is largely due to an increased risk of obesity, diabetes, and cardiovascular disease. This comparison of youths with first-episode psychosis...
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JCP
Original Research

January 3, 2017

The risks of medication for bipolar disorder during pregnancy must be weighed carefully against the risks of untreated illness. Find out whether exposure to maternal illness and/or to medication...
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JCP
Original Research

December 28, 2016

Irritability and anger attacks affect about one-third of patients with major depressive disorder. This study by Fava et al evaluates adjunctive brexpiprazole as a strategy for patients with MDD...
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JCP
Original Research

December 28, 2016

Cortical thinning, identified during prodromal Alzheimer's disease, is a "candidate" biomarker used in clinical therapy trials. This study looked at change in cortical thickness after 1 year of donepezil...
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JCP
Original Research

December 28, 2016

Twenty US veterans kill themselves every day. What more can be done to stop this self-slaughter? Dialectical behavior therapy (DBT), which combines behavioral intervention with cognitive techniques of mindfulness,...
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JCP
Original Research

December 28, 2016

Understand the association between depression and levels of C-reactive protein (CRP) and fractional exhaled nitric oxide (FeNO).
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JCP
Original Research

December 28, 2016

Cognitive difficulties may be overlooked in treating patients with bipolar or unipolar depression, but 20% of patients report such symptoms. The authors of this article reanalyzed data from 2...
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JCP
Original Research

December 28, 2016

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JCP
Original Research

December 28, 2016

What's the next step when a patient doesn' t respond to an antipsychotic? Should you augment, switch medications, wait and see, or raise the dose? Read this study in...
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JCP
Original Research

December 28, 2016

Antipsychotics such as risperidone and aripiprazole are efficacious for controlling behavioral symptoms in children with intellectual disability or autism spectrum disorder, but they are also associated with adverse reactions...
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JCP
Original Research

December 28, 2016

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JCP
Original Research

December 28, 2016

When your 18- to 26-year-old patients respond poorly to the antipsychotic prescribed for their first episode of psychosis, what else can you try? In this RCT, taurine, which acts...
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JCP
Original Research

December 28, 2016

Are rates of depression and bipolar disorder going up? If so, why? To answer these questions, this Danish study looked at trends in diagnosed affective disorders over the last...
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JCP
Original Research

December 28, 2016

Read a study whether the Montgomery-Asberg Depression Rating Scale (MADRS) can assess the rapid onset of the antidepressant effect of a treatment in patients.
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JCP
Original Research

December 28, 2016

The worries that characterize generalized anxiety disorder are so pervasive and excessive that they distort cognition and create a considerable burden of illness. See what the authors of this...
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JCP
Original Research

December 6, 2016

Patients with insomnia and disrupted sleep are at increased risk of suicide. Check out this article to see if researchers found a link between antisuicidal response to ketamine and...
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JCP
Original Research

November 23, 2016

Several antipsychotics have shown efficacy for schizophrenia in controlled settings, but how effective are they in the long-term treatment of individuals in community settings? Learn how 7 antipsychotics compared...
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