Original Research

JCP
CYP2D6 Genotyping and Adverse Drug Reactions in Depression
Original Research

January 17, 2024

Genetic testing of CYP2D6 did not show that predicted poor drug metabolism led to increased adverse drug reactions in patients with depression.
, , , et al
JCP
Efficacy and Safety of Iloperidone in Bipolar Mania
Original Research

January 15, 2024

At 4 weeks of treatment, patients receiving iloperidone showed significant improvement on the Young Mania Rating Scale versus those receiving placebo.
, , , et al
PCC
Impact of an Inpatient Medical Student–Run Bingo Group
Original Research

January 11, 2024

The bingo group provides leadership opportunities for medical students lacking advanced group training, enables student integration into the inpatient psychiatry unit, and reduces stigma.
,
PCC
Recurrent Hospital Visits and BPD
Original Research

January 9, 2024

This study examined associations between patients with borderline personality disorder symptoms and their hospital presentations and explored effects of inpatient length of stay on time to hospital re-presentation.
, , , et al
JCP
Clinical Outcomes of IV Ketamine for Depression
Original Research

January 8, 2024

Short-term clinical trials found intravenous (IV) ketamine to be effective in reducing depressive symptoms. This study assessed longer-term outcomes of IV ketamine for depression and explored treatment and patient...
, , , et al
JCP
Oral Anticoagulants, Atrial Fibrillation, and Mental Illness
Original Research

January 3, 2024

People with atrial fibrillation (AF) and comorbid mental illness are less often prescribed an oral anticoagulant (OAC) for AF-related stroke prevention. This study examined how mental illness interacts with...
, , , et al
JCP
Guideline Concordance in Major Depressive Disorder
Original Research

January 3, 2024

This study created a new score to measure treatment guideline adherence and found that following guidelines resulted in lower MDD symptom severity.
, , , et al
PCC
Children With ADHD During the COVID-19 Pandemic
Original Research

January 2, 2024

Stresses caused by the COVID-19 pandemic may negatively affect management of ADHD in youth. This study assessed the perceived impact of the COVID-19 pandemic on treatment and quality of...
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PCC
Sleep Quality in Patients With Schizophrenia
Original Research

December 28, 2023

Most patients with schizophrenia suffered significantly from poor sleep quality, deleteriously impacting their daytime functioning.
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JCP
Outcome Predictors in Youth With Mental Disorders
Original Research

December 27, 2023

This retrospective analysis of clinical parameters in youth hospitalized for psychiatric treatment assessed magnitude and correlates of symptom response, global illness response, social functioning, out-of-home placement, and length of...
, , , et al
JCP
Long-Term Safety and Efficacy of Zuranolone in MDD
Original Research

December 27, 2023

Most patients with MDD achieved response after 14 days of zuranolone treatment. For patients who responded to their first treatment, the time to repeat treatment was over 4 months.
, , , et al
JCP
Metformin for SGA-Induced Weight Gain
Original Research

December 20, 2023

Pediatric patients are vulnerable to antipsychotic-induced weight gain (AIWG). This study assessed the effectiveness of metformin on AIWG and explored whether timing of metformin initiation and premorbid obesity moderated...
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JCP
A Comparison of 3 Scales for Measuring Adolescent Depression
Original Research

December 18, 2023

Three patient-reported outcomes—Patient Health Questionnaire for Adolescents, Quick Inventory of Depressive Symptomatology–Self-Report, and Very Quick Inventory of Depressive Symptomatology–Self-Report—can assess depressive symptom severity and change over time. Scores on...
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JCP
Social Media Images Can Predict Suicide Risk
Original Research

November 29, 2023

Recent studies predicting signs of suicide risk from social media using artificial intelligence have been limited by methodological and conceptual factors. This study presents an interpretable prediction model of...
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JCP
Decrease in Alcohol Use Disorder Symptoms With Semaglutide
Original Research

November 27, 2023

Six patients who screened positive for alcohol use disorder (AUD) received semaglutide for weight loss. All subsequently showed significant improvement in AUD symptoms.
, , , et al
JCP
Acceptance and Mindfulness-Based Exposure Therapy for PTSD After Cardiac Arrest
Original Research

November 22, 2023

Eighty percent of patients had significant response to therapy, with 70% showing diagnostic remission of PTSD after 8 sessions.
, , , et al
PCC
Psychiatric Disorders Among Child Welfare Custody Patients
Original Research

November 21, 2023

Children and adolescents in the child welfare system are associated with a higher risk of mental health problems. Factors that can prevent psychiatric comorbidities in the child welfare population...
, , , et al
JCP
Trends in Telemental Health Utilization in the US
Original Research

November 20, 2023

The proportion of mental health visits delivered via telemental health increased from 0.002% to 0.162% between 2010¬–2019. Patients aged 18–34 and those in the western US had the highest...
, , , et al
PCC
Emotion Regulation, Fear of COVID, and Quality of Life
Original Research

November 16, 2023

Those providing mental health services during pandemics should bolster their patients’ use of cognitive reappraisal rather than expressive suppression and positive affect rather than negative affect to improve their...
, , , et al
JCP
Machine Learning Prediction of Quality of Life Improvement During Antidepressant Treatment of Patients With Major Depressive Disorder: A STAR*D and CAN-BIND-1 Report
Original Research

November 15, 2023

Quality of life is an important patient-centric outcome. Using machine learning methods, this study found that quality of life improvement with antidepressant treatment can be predicted using early depression...
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PCC
Effect of Care Burden and Personality Traits of Caregivers on Schizophrenia Patients
Original Research

November 14, 2023

The temperament and character traits of caregivers may affect the social functionality of patients with schizophrenia.
, , , et al
JCP
Smoking in Borderline Patients
Original Research

November 8, 2023

This study assessed predictors of smoking in borderline personality disorder and compared smoking prevalence in recovered vs non-recovered patients.
, , , et al
JCP
Medication Adherence in a Transdiagnostic FEP Sample
Original Research

November 1, 2023

Thirty percent of patients with first-episode psychosis showed non-adherence to medication over a period of up to 5½ years. Treatment factors such as the type or dose of antipsychotic...
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JCP
Training for Lasting Trauma-Informed Change
Original Research

October 30, 2023

Two-day training in trauma-informed care (TIC) significantly improved understanding and implementation of TIC at both the individual and systemwide levels.
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