David McDonnell, MD | Psychiatrist.com

Olanzapine/Samidorphan Effects on Weight Gain

Original Research

Olanzapine/Samidorphan Effects on Weight Gain

January 2, 2025

Treatment with a combination of olanzapine and samidorphan was associated with less weight gain and reduced risk of reaching ≥7% or ≥10% gain in body weight versus olanzapine over...

Christoph U. Correll, Michael J. Doane, David McDonnell, et al

Long-Term Safety and Treatment Effect of Olanzapine/Samidorphan

Original Research

Long-Term Safety and Treatment Effect of Olanzapine/Samidorphan

December 4, 2024

During up to 4 years of treatment, the combination of olanzapine/samidorphan was safe and well-tolerated, and patients’ symptoms remained stable.

Jacob S. Ballon, René S. Kahn, Christina Arevalo, et al

Original Research

Olanzapine Plus Samidorphan in Schizophrenia With AUD

March 10, 2020

Alcohol use disorder is comorbid in 33% of US patients with schizophrenia. Testing the tolerability of olanzapine and samidorphan until the first event of exacerbation of disease symptoms is...

Mary F. Brunette, Christoph U. Correll, Stephanie S. O' Malley, et al

Original Research

Olanzapine/Samidorphan for Schizophrenia

March 3, 2020

Read a study evaluating the antipsychotic efficacy and safety of OLZ/SAM compared with placebo in patients with an acute exacerbation of schizophrenia.

Steven G. Potkin, Jelena Kunovac, Bernard L. Silverman, et al

Original Research

An 8-Week, Double-Blind, Randomized, Placebo-Controlled Study of Olanzapine Long-Acting Injection in Acutely Ill Patients With Schizophrenia

May 11, 2008

John Lauriello, Tim Lambert, Scott Andersen, et al