Hiroyoshi Takeuchi, MD, PhD
Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan, Division of Drug Informatics, Keio University Faculty of Pharmacy, Tokyo, Japan
Letter to the Editor
Does the Onset of Efficacy for Agitation Vary Depending on the Administration Route of Antipsychotics?
March 20, 2024
As choice of administration route is crucial during psychiatric emergencies, the authors stress the need for RCTs comparing onset of efficacy for agitation across different administration routes of the...
Review Article
Central and Peripheral Pharmacokinetics of Antipsychotics
July 28, 2020
Pharmacokinetics of antipsychotics are generally slower centrally than peripherally. This review examined the possible dissociation between central D2 receptor occupancy with antipsychotics and their peripheral blood concentrations.
Article
Quantifying Intraindividual Variations in Plasma Clozapine Levels: A Population Pharmacokinetic Approach
May 25, 2016
Clozapine is the most effective antipsychotic used in the treatment of refractory schizophrenia. But how do factors like smoking and caffeine intake affect plasma clozapine levels? The authors of...
