Hiroyuki Uchida, MD, PhD

Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan

JCP
IV Hydroxyzine vs Haloperidol for Delirium
Original Research

January 6, 2025

Hydroxyzine showed a significantly higher rate of delirium improvement than haloperidol, with no significant difference in the time to improvement.
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JCP
Original Research

November 9, 2021

This study compared proportions of patients with comorbid psychiatric disorders among those hospitalized for either pulmonary embolism, a common cause of sudden cardiac arrest in psychiatric patients, or acute...
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JCP
Meta-Analysis

February 23, 2021

Single-daily-dose regimens are easier for patients to follow than multiple-dose regimens and may increase adherence. But do they work as well? And are they safe? Read this meta-analysis to...
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JCP
Original Research

January 12, 2021

Although long-acting injectable (LAI) antipsychotics show benefit in the early stages of schizophrenia, they are mostly used later in the illness. This study assessed clinical and functional improvement with...
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JCP
Review Article

July 28, 2020

Pharmacokinetics of antipsychotics are generally slower centrally than peripherally. This review examined the possible dissociation between central D2 receptor occupancy with antipsychotics and their peripheral blood concentrations.
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JCP
Original Research

December 4, 2018

Poor treatment adherence masks the true extent of placebo effects in trials of antipsychotics in schizophrenia. Can use of an injectable placebo in double-blind trials of long-acting injectable antipsychotics...
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JCP
Original Research

October 17, 2017

Placebo effects are a common obstacle in the search for Alzheimer's disease treatments. This analysis of data from the large CATIE-AD study investigates ways to screen out potential placebo...
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JCP
Article

August 23, 2017

Few data have been published to guide antipsychotic treatment of psychosis in Alzheimer's disease. This population analysis was conducted to determine the optimal dose of amisulpride in order to...
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JCP
Article

February 22, 2017

A key to improving prognosis in bipolar depression may lie in analysis of specific symptoms. This reanalysis of the STEP-BD dataset provides clues to help you determine which patients...
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JCP
Article

December 28, 2016

Since older patients are known to be hypersensitive to antipsychotics, are they vulnerable to developing hyperprolactinemia with these drugs? This post hoc study looked at whether the dopamine D2/3...
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JCP
Article

October 26, 2016

When your patients with schizophrenia insufficiently respond to antipsychotic treatment, do you increase the dose? Do you check their plasma drug concentration? Read this CME article to find out...
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JCP
Article

April 22, 2015

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