Marcos Sanches, PhD

Therapeutic options for treatment-resistant bipolar depression (TRBD) are limited. Since insulin resistance (IR) increases risk of TRBD, this study examined if the insulin sensitizer metformin reversed IR and improved...

Augmentation of antidepressants with aripiprazole is effective in treating late-life depression. As an antipsychotic medication, however, aripiprazole potentially leads to extrapyramidal side effects (EPS). Read this article to learn...