
Marlene P. Freeman, MD
Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts
Original Research
Effect of Benzodiazepines on Antidepressant Effects of Ketamine
November 14, 2022
Findings of studies examining the impact of benzodiazepines on antidepressant effects of ketamine are contradictory. This study assessed whether concomitant oral benzodiazepines differentially affected treatment response to ketamine versus...
ASCP Corner
Neuroactive Steroids for Depression: Potential Implications for PMDD
June 8, 2021
Recent promising data indicate that neuroactive steroids could have a role in treating depression. This article discusses the mechanisms behind potential beneficial effects in premenstrual dysphoric disorder as well.
Original Research
Adjunctive Pimavanserin and Sleep/Wakefulness in MDD
December 1, 2020
Adjunctive pimavanserin can reduce depressive symptoms and improve function in patients with major depression and inadequate antidepressant response. This analysis evaluated the effects of adjunctive pimavanserin on sleep/wakefulness disturbances.