Major Depressive Disorder (MDD) is a debilitating condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest in daily activities. Understanding its underlying causes and effective treatments is crucial for patient well-being. The Journal of Clinical Psychiatry provides a comprehensive look into MDD, offering evidence-based therapeutic approaches and the latest research findings. Our expert editors ensure content is relevant and actionable, aiding psychiatrists in offering holistic care to those grappling with depression.
Depression and Major Depressive Disorder
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Recently published articles about Depression (MDD)
Clinical and Practical Psychopharmacology
N-Acetylcysteine Augmentation for Patients With Major Depressive Disorder and Bipolar Depression
February 18, 2021
Two recent meta-analyses found little effect of N-acetylcysteine augmentation in MDD or bipolar depression, although some past research has indicated its efficacy. In this article, Dr Andrade takes a...
Original Research
ECT for Depressed Patients With and Without BPD
January 19, 2021
Borderline personality disorder (BPD) is thought to lead to poor response to electroconvulsive therapy (ECT) in depressed patients. This study assessed symptom-severity outcomes among depressed patients with and without...
Original Research
Efficacy of Citalopram Treatment in Bipolar Depression
January 12, 2021
Antidepressants are widely used to treat bipolar illness, though their effectiveness in this disorder has not been established. This randomized, double-blind, placebo-controlled trial assessed the efficacy and safety of...
