Major Depressive Disorder (MDD) is a debilitating condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest in daily activities. Understanding its underlying causes and effective treatments is crucial for patient well-being. The Journal of Clinical Psychiatry provides a comprehensive look into MDD, offering evidence-based therapeutic approaches and the latest research findings. Our expert editors ensure content is relevant and actionable, aiding psychiatrists in offering holistic care to those grappling with depression.
Depression and Major Depressive Disorder
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Recently published articles about Depression (MDD)
Original Research
Cost-Effectiveness of "Next-Step" Depression Treatment Strategies
December 18, 2018
Aripiprazole is commonly prescribed as a next-step pharmacotherapy for treatment-resistant depression, but its cost-effectiveness as an adjunct to antidepressants is unknown. Read this article to learn how the cost-effectiveness...
Original Research
Sudden Improvement in Symptoms During Antidepressant Clinical Trials
December 4, 2018
If a patient's depressive symptoms subside very quickly after antidepressant treatment is initiated, do those gains represent a true and lasting response? This study examined whether sudden improvement in...
Original Research
Depression, Cognition, and Functional Impairment
November 13, 2018
Depression is strongly associated with functional impairment. Some hypothesize that cognitive dysfunction, which is also often associated with depression, might mediate the impact of depression on functioning. This study...
Original Research
Cerebral Blood Flow After Late-Life Depression Treatment
October 23, 2018
Could cerebrovascular disease be a factor in your elderly patient's depression? This article investigated the association of white matter hyperintensities and cerebral blood flow with late-life depressive symptoms and...
