Major Depressive Disorder (MDD) is a debilitating condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest in daily activities. Understanding its underlying causes and effective treatments is crucial for patient well-being. The Journal of Clinical Psychiatry provides a comprehensive look into MDD, offering evidence-based therapeutic approaches and the latest research findings. Our expert editors ensure content is relevant and actionable, aiding psychiatrists in offering holistic care to those grappling with depression.
Depression and Major Depressive Disorder
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Recently published articles about Depression (MDD)
Original Research
Antisuicidal Effects of Ketamine in Patients With Comorbid AUD
April 24, 2024
Intranasal ketamine induced rapid antidepressant effects versus placebo but did not significantly change suicidal ideation scores in patients with alcohol use disorder and suicidal ideation with past attempt.
Case Report
Serotonin Syndrome and Dextromethorphan Toxicity Caused by Fluoxetine and Bupropion-Dextromethorphan Interaction
April 3, 2024
Addition of bupropion-dextromethorphan (BUP/DXM) to existing fluoxetine treatment resulted in serotonin syndrome within 3 days, with symptoms prompting presentation to the ED 5 days after discontinuation of BUP/DXM.
