The Journal of
Clinical Psychiatry

Volume 69 • 2008 • 10

Original Research

The History and Current State of Antidepressant Clinical Trial Design: A Call to Action for Proof-of-Concept Studies

J Clin Psychiatry 2008;69(10):1513-1528

Alan J. Gelenberg, MD ; Michael E. Thase, MD ; Roger E. Meyer, MD ; Frederick K. Goodwin, MD ; Martin M. Katz, PhD ; Helena Chmura Kraemer, PhD ; William Z. Potter, MD ; Richard C. Shelton, MD ; Maurizio Fava, MD ; Arif Khan, MD ; Madhukar H. Trivedi, MD ; Philip T. Ninan, MD ; John J. Mann, MD ; Susan Bergeson, MBA ; Jean Endicott, PhD ; James H. Kocsis, MD ; Andrew C. Leon, PhD ; Husseini K. Manji, MD ; Jerrold F. Rosenbaum, MD

Original Research

A Pooled Analysis of Gender and Trauma-Type Effects on Responsiveness to Treatment of PTSD With Venlafaxine Extended Release or Placebo

J Clin Psychiatry 2008;69(10):1529-1539

Barbara O. Rothbaum, PhD, ABPP ; Jonathan R. T. Davidson, MD ; Dan J. Stein, MD, PhD ; Ron Pedersen, MS ; Jeff Musgnung, MT ; Xiao Wei Tian, MS ; Saeeduddin Ahmed, MD ; David S. Baldwin, DM, FRCPsych

Original Research

Patterns of Atypical Antipsychotic Subtherapeutic Dosing Among Oregon Medicaid Patients

J Clin Psychiatry 2008;69(10):1540-1547

Daniel M. Hartung, PharmD, MPH ; Jennifer P. Wisdom, PhD, MPH ; David A. Pollack, MD ; Ann M. Hamer, PharmD ; Dean G. Haxby, PharmD ; Luke Middleton, BS ; Bentson H. McFarland, MD, PhD

Original Research

A Cross-Sectional Study of Patients' Perspectives on Adherence to Antipsychotic Medication: Depot Versus Oral

J Clin Psychiatry 2008;69(10):1548-1556

Maxine X. Patel, MBBS, MSc, MRCPsych ; Nicole de Zoysa, MSc ; Morris Bernadt, MBChB, MRCPsych ; Anthony S. David, FRCP, FRCPsych, MD, MSc

Original Research

Efficacy and Safety of Doxepin 1 mg, 3 mg, and 6 mg in Elderly Patients With Primary Insomnia: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

J Clin Psychiatry 2008;69(10):1557-1564

Martin Scharf, PhD ; Roberta Rogowski, RN ; Steven Hull, MD ; Martin Cohn, MD ; David Mayleben, PhD ; Neil Feldman, MD ; Larry Ereshefsky, PhD ; Alan Lankford, PhD ; Thomas Roth, PhD

Original Research

Serotonin-System Polymorphisms (5-HTTLPR and -1438G/A) and Responses of Patients With Bulimic Syndromes to Multimodal Treatments

J Clin Psychiatry 2008;69(10):1565-1571

Howard Steiger, PhD ; Ridha Joober, MD, PhD ; Lise Gauvin, PhD ; Kenneth R. Bruce, PhD ; Jodie Richardson, BSc ; Mimi Israel, MD ; Annelie S. Anestin, BA ; Patricia Groleau, BA

Original Research

Is Flunarizine a Long-Acting Oral Atypical Antipsychotic? A Randomized Clinical Trial Versus Haloperidol for the Treatment of Schizophrenia

J Clin Psychiatry 2008;69(10):1572-1579

Luísa W. Bisol, MD, PhD ; Miriam G. Brunstein, MD, PhD ; Gustavo L. Ottoni, MD ; Fernanda L. P. Ramos, MD ; Daniela L. Borba, BA ; Claudiane S. Daltio, MD ; Ricardo V. de Oliveira, MSc ; Gisele E. G. Paz, BS ; Sayuri E. de Souza, BS ; Rodrigo A. Bressan, MD, PhD ; Diogo R. Lara, MD, PhD

Original Research

Tardive Dyskinesia and the 3-Year Course of Schizophrenia: Results From a Large, Prospective, Naturalistic Study

J Clin Psychiatry 2008;69(10):1580-1588

Haya Ascher-Svanum, PhD ; Baojin Zhu, PhD ; Douglas Faries, PhD ; Xiaomei Peng, MD ; Bruce J. Kinon, MD ; Mauricio Tohen, MD

Original Research

Antidepressant-Associated Mood Elevations in Bipolar II Disorder Compared With Bipolar I Disorder and Major Depressive Disorder: A Systematic Review and Meta-Analysis

J Clin Psychiatry 2008;69(10):1589-1601

David J. Bond, MD, FRCPC ; Melissa M. Noronha, RPN ; Marcia Kauer-Sant'Anna, MD, PhD ; Raymond W. Lam, MD, FRCPC ; Lakshmi N. Yatham, MBBS, FRCPC, MRCPsych (UK)

Article

Perinatal Disorders: Advancing Public Health Opportunities

J Clin Psychiatry 2008;69(10):1602-1605

Katherine L. Wisner, MD, MS ; Sarah Hudson, MPH, DrPH ; Scholle Bradley Stein, MD, PhD

Article

Gender Differences in Generalized Anxiety Disorder: Results From the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)

J Clin Psychiatry 2008;69(10):1606-1616

Oriana Vesga-López, MD ; Franklin R. Schneier, MD ; Samuel Wang, BS ; Richard G. Heimberg, PhD ; Shang-Min Liu, MS ; Deborah S. Hasin, PhD ; Carlos Blanco, MD, PhD

Article

Axis I Psychopathology and Functional Impairment at the Third Month of Pregnancy: Results From the Perinatal Depression-Research and Screening Unit (PND-ReScU) Study

J Clin Psychiatry 2008;69(10):1617-1624

Chiara Borri, MD, PhD ; Mauro Mauri, MD ; Annalisa Oppo, DPsych ; Susanna Banti, MD, PhD ; Cristina Rambelli, MD ; Daniele Ramacciotti, MD ; Maria S. Montagnani, MD ; Valeria Camilleri, MD ; Sonia Cortopassi, MD ; Amparo Bettini, DPsych ; Serena Ricciardulli, DPsych ; Paola Rucci, DStat ; Simone Montaresi, DSci ; Giovanni B. Cassano, MD

Article

A Closer Look at Depression in Mothers Who Kill Their Children: Is It Unipolar or Bipolar Depression?

J Clin Psychiatry 2008;69(10):1625-1631

Jeong-Hyun Kim, MD ; Sang Sub Choi, MD, PhD ; Kyooseob Ha, MD, PhD

Academic Highlights

International Consensus Group on the Evidence-Based Pharmacologic Treatment of Bipolar I and II Depression

J Clin Psychiatry 2008;69(10):1632-1646

Siegfried Kasper, M.D. ; Joseph R. Calabrese, M.D. ; Gordon Johnson, M.B.B.S. ; Osamu Tajima, Ph.D. ; Eduard Vieta, M.D., Ph.D. ; Adele C. Viguera, M.D. ; Lakshmi N. Yatham, M.B.B.S., F.R.C.P.C. ; Allan H. Young, M.D., F.R.C.Psych

Academic Highlights

Obsessive-Compulsive Disorder: Strategies for Optimal Treatment

J Clin Psychiatry 2008;69(10):1647-1657

Eric Hollander, M.D. ; Jonathan S. Abramowitz, Ph.D., ABPP ; Lorrin M. Koran, M.D. ; Stefano Pallanti, M.D., Ph.D.

ASCP Corner

The Search for Knowledge: Developing the American Psychiatric Association's Practice Guideline for Major Depressive Disorder

J Clin Psychiatry 2008;69(10):1658-1659

Alan J. Gelenberg, MD

Letter to the Editor

High-Dose Olanzapine Versus Clozapine

J Clin Psychiatry 2008;69(10):1660

Jeffrey A. Mattes, MD

Letter to the Editor

Drs. Meltzer and Jayathilake Reply

J Clin Psychiatry 2008;69(10):1660-1661

Herbert Y. Meltzer, MD ; Karu Jayathilake, PhD

Letter to the Editor

Depression in Physicians: Hyperfunctioning Depression or Professional Depression?

J Clin Psychiatry 2008;69(10):1661

Nagy A. Youssef, MD

Letter to the Editor

Drs. Schwenk and Leja Reply

J Clin Psychiatry 2008;69(10):1661-1662

Thomas L. Schwenk ; Loretta M. Leja

Letter to the Editor

ECT Not Proven for Atypical Depression

J Clin Psychiatry 2008;69(10):1662-1662

Conrad M. Swartz

Letter to the Editor

Dr. McClintock and Colleagues Reply

J Clin Psychiatry 2008;69(10):1662-1663

Shawn M. McClintock ; Mustafa M. Husain ; A. John Rush ; Cynthia Claassen ; Melanie M. Biggs ; Rebecca G. Knapp ; Martina Mueller ; Max Fink ; Samuel H. Bailine ; Teresa A. Rummans ; Shirlene Sampson ; Georgios Petrides ; Charles H. Kellner ; Sarah H. Lisanby

Educational Activity

Evaluating and Diagnosing Fibromyalgia and Comorbid Psychiatric Disorders

J Clin Psychiatry 2008;69(10):e28

Lesley M. Arnold, MD ; Laurence A. Bradley, PhD ; Daniel J. Clauw, MD ; Jennifer M. Glass, PhD ; Don L. Goldenberg, MD, Chair

Educational Activity

Effective Agents in Treating Bipolar Depression

J Clin Psychiatry 2008;69(10):e29

Andrew A. Nierenberg, M.D.

Educational Activity

Practical Strategies for Diagnosing and Treating Depression in Women: Menopausal Transition

J Clin Psychiatry 2008;69(10):e30

Claudio N. Soares, M.D., Ph.D., F.R.C.P.C.

Book Review

The American Psychiatric Publishing Textbook of Suicide Assessment and Management

J Clin Psychiatry 2008;69(10):1664

Linda S. Godleski, MD

Book Review

"The American Psychiatrc Publishing Textbook of Geriatric Psychiatry, 3rd ed." and "Essentials of Geriatric Psychiatry"

J Clin Psychiatry 2008;69(10):1664-1665

Anand Kumar, MD

Book Review

Medical Psychiatry: The Quick Reference

J Clin Psychiatry 2008;69(10):1665

Kelly Brogan, MD ; Carol A. Bernstein, MD

Volume 69 • 2008 • 10

Original Research

The History and Current State of Antidepressant Clinical Trial Design: A Call to Action for Proof-of-Concept Studies

A Pooled Analysis of Gender and Trauma-Type Effects on Responsiveness to Treatment of PTSD With Venlafaxine Extended Release or Placebo

Patterns of Atypical Antipsychotic Subtherapeutic Dosing Among Oregon Medicaid Patients

A Cross-Sectional Study of Patients' Perspectives on Adherence to Antipsychotic Medication: Depot Versus Oral

Efficacy and Safety of Doxepin 1 mg, 3 mg, and 6 mg in Elderly Patients With Primary Insomnia: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

Serotonin-System Polymorphisms (5-HTTLPR and -1438G/A) and Responses of Patients With Bulimic Syndromes to Multimodal Treatments

Is Flunarizine a Long-Acting Oral Atypical Antipsychotic? A Randomized Clinical Trial Versus Haloperidol for the Treatment of Schizophrenia

Tardive Dyskinesia and the 3-Year Course of Schizophrenia: Results From a Large, Prospective, Naturalistic Study

Antidepressant-Associated Mood Elevations in Bipolar II Disorder Compared With Bipolar I Disorder and Major Depressive Disorder: A Systematic Review and Meta-Analysis

Article

Perinatal Disorders: Advancing Public Health Opportunities

Gender Differences in Generalized Anxiety Disorder: Results From the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)

Axis I Psychopathology and Functional Impairment at the Third Month of Pregnancy: Results From the Perinatal Depression-Research and Screening Unit (PND-ReScU) Study

A Closer Look at Depression in Mothers Who Kill Their Children: Is It Unipolar or Bipolar Depression?

Academic Highlights

International Consensus Group on the Evidence-Based Pharmacologic Treatment of Bipolar I and II Depression

Obsessive-Compulsive Disorder: Strategies for Optimal Treatment

ASCP Corner

The Search for Knowledge: Developing the American Psychiatric Association's Practice Guideline for Major Depressive Disorder

Letter to the Editor

High-Dose Olanzapine Versus Clozapine

Drs. Meltzer and Jayathilake Reply

Depression in Physicians: Hyperfunctioning Depression or Professional Depression?

Drs. Schwenk and Leja Reply

ECT Not Proven for Atypical Depression

Dr. McClintock and Colleagues Reply

Educational Activity

Evaluating and Diagnosing Fibromyalgia and Comorbid Psychiatric Disorders

Effective Agents in Treating Bipolar Depression

Practical Strategies for Diagnosing and Treating Depression in Women: Menopausal Transition

Book Review

The American Psychiatric Publishing Textbook of Suicide Assessment and Management

"The American Psychiatrc Publishing Textbook of Geriatric Psychiatry, 3rd ed." and "Essentials of Geriatric Psychiatry"

Medical Psychiatry: The Quick Reference

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Volume 69 • 2008 • 10

Original Research

The History and Current State of Antidepressant Clinical Trial Design: A Call to Action for Proof-of-Concept Studies

A Pooled Analysis of Gender and Trauma-Type Effects on Responsiveness to Treatment of PTSD With Venlafaxine Extended Release or Placebo

Patterns of Atypical Antipsychotic Subtherapeutic Dosing Among Oregon Medicaid Patients

A Cross-Sectional Study of Patients' Perspectives on Adherence to Antipsychotic Medication: Depot Versus Oral

Efficacy and Safety of Doxepin 1 mg, 3 mg, and 6 mg in Elderly Patients With Primary Insomnia: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

Serotonin-System Polymorphisms (5-HTTLPR and -1438G/A) and Responses of Patients With Bulimic Syndromes to Multimodal Treatments

Is Flunarizine a Long-Acting Oral Atypical Antipsychotic? A Randomized Clinical Trial Versus Haloperidol for the Treatment of Schizophrenia

Tardive Dyskinesia and the 3-Year Course of Schizophrenia: Results From a Large, Prospective, Naturalistic Study

Antidepressant-Associated Mood Elevations in Bipolar II Disorder Compared With Bipolar I Disorder and Major Depressive Disorder: A Systematic Review and Meta-Analysis

Article

Perinatal Disorders: Advancing Public Health Opportunities

Gender Differences in Generalized Anxiety Disorder: Results From the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)

Axis I Psychopathology and Functional Impairment at the Third Month of Pregnancy: Results From the Perinatal Depression-Research and Screening Unit (PND-ReScU) Study

A Closer Look at Depression in Mothers Who Kill Their Children: Is It Unipolar or Bipolar Depression?

Academic Highlights

International Consensus Group on the Evidence-Based Pharmacologic Treatment of Bipolar I and II Depression

Obsessive-Compulsive Disorder: Strategies for Optimal Treatment

ASCP Corner

The Search for Knowledge: Developing the American Psychiatric Association's Practice Guideline for Major Depressive Disorder

Letter to the Editor

High-Dose Olanzapine Versus Clozapine

Drs. Meltzer and Jayathilake Reply

Depression in Physicians: Hyperfunctioning Depression or Professional Depression?

Drs. Schwenk and Leja Reply

ECT Not Proven for Atypical Depression

Dr. McClintock and Colleagues Reply

Educational Activity

Evaluating and Diagnosing Fibromyalgia and Comorbid Psychiatric Disorders

Effective Agents in Treating Bipolar Depression

Practical Strategies for Diagnosing and Treating Depression in Women: Menopausal Transition

Book Review

The American Psychiatric Publishing Textbook of Suicide Assessment and Management

"The American Psychiatrc Publishing Textbook of Geriatric Psychiatry, 3rd ed." and "Essentials of Geriatric Psychiatry"

Medical Psychiatry: The Quick Reference

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