The Journal of
Clinical Psychiatry

Volume 77 • 2016 • 5

Meta-Analysis

Early Onset of Response With Selective Serotonin Reuptake Inhibitors in Obsessive-Compulsive Disorder: A Meta-Analysis

J Clin Psychiatry 2016;77(5):e605-e611

Yasmin Issari ; Ewgeni Jakubovski, MA ; Christine A. Bartley, BA ; Christopher Pittenger, MD, PhD ; Michael H. Bloch, MD, MS

Meta-Analysis

Demographic Variables, Design Characteristics, and Effect Sizes of Randomized, Placebo-Controlled, Monotherapy Trials of Major Depressive Disorder and Bipolar Depression

J Clin Psychiatry 2016;77(5):e619-e624

George I. Papakostas, MD ; Max A. Martinson, BSc ; Maurizio Fava, MD ; Nadia Iovieno, MD

Original Research

Clozapine and Risperidone in Moderately Refractory Schizophrenia: A 6-Month Randomized Double-Blind Comparison

J Clin Psychiatry 2016;77(5):628-634

Nina R. Schooler, PhD ; Stephen R. Marder, MD ; K. N. R. Chengappa, MD ; Georgios Petrides, MD ; Donna Ames, MD ; William C. Wirshing, MD ; Marjorie McMeniman, PhD ; Robert W. Baker, MD ; Haranath Parepally, MD ; Daniel Umbricht, MD ; John M. Kane, MD

Original Research

Efficacy Outcomes From 3 Clinical Trials of Edivoxetine as Adjunctive Treatment for Patients With Major Depressive Disorder Who Are Partial Responders to Selective Serotonin Reuptake Inhibitor Treatment

J Clin Psychiatry 2016;77(5):635-642

Susan G. Ball, PhD ; Margaret B. Ferguson, PharmD ; James M. Martinez, MD ; Beth A. Pangallo, RN ; E. Serap Monkul Nery, MD ; Mary Anne Dellva, MS ; JonDavid Sparks, PhD ; Qi Zhang, PhD ; Peng Liu, PhD ; Mark Bangs, MD ; Celine Goldberger, MD

Original Research

The Course of Suicide Risk Following Traumatic Injury

J Clin Psychiatry 2016;77(5):648-653

Richard A. Bryant, PhD ; Meaghan L. O' Donnell, PhD ; David Forbes, PhD ; Alexander C. McFarlane, MD ; Derrick Silove, MD ; Mark Creamer, PhD

Original Research

Long-Term Efficacy, Safety, and Tolerability of l-Methylfolate Calcium 15 mg as Adjunctive Therapy With Selective Serotonin Reuptake Inhibitors: A 12-Month, Open-Label Study Following a Placebo-Controlled #05#

J Clin Psychiatry 2016;77(5):654-660

John M. Zajecka, MD ; Maurizio Fava, MD ; Richard C. Shelton, MD ; Lori W. Barrentine, MS, PA-C ; Page Young, BS ; George I. Papakostas, MD

Original Research

Correlation of Clinical Response With Homocysteine Reduction During Therapy With Reduced B Vitamins in Patients With MDD Who Are Positive for MTHFR C677T or A1298C Polymorphism: A Randomized, Double-Blind, Placebo-Controlled Study

J Clin Psychiatry 2016;77(5):668-671

Arnold W. Mech, MD ; Andrew Farah, MD, DFAPA

Original Research

Age at the Time of Exposure to Trauma Modulates the Psychopathological Profile in Patients With Early Psychosis

J Clin Psychiatry 2016;77(5):e612-e618

Luis Alameda, MD ; Philippe Golay, PhD ; Philipp S. Baumann, MD ; Carina Ferrari, MSc ; Kim Q. Do, PhD ; Philippe Conus, MD

Original Research

Adherence to Antidepressants Is Associated With Lower Mortality: A 4-Year Population-Based Cohort Study

J Clin Psychiatry 2016;77(5):e566-e572

Amir Krivoy, MD ; Ran D. Balicer, MD, PhD ; Becca Feldman, PhD ; Moshe Hoshen, PhD ; Gil Zalsman, MD, MHA ; Abraham Weizman, MD ; Gal Shoval, MD

Original Research

Comparative Risk of Seizure With Use of First- and Second-Generation Antipsychotics in Patients With Schizophrenia and Mood Disorders

J Clin Psychiatry 2016;77(5):e573-e579

Chi-Shin Wu, MD, PhD ; Sheng-Chang Wang, MD, MSc ; I-Jin Yeh, MD ; Shi-Kai Liu, MD

Original Research

Long-Term Outcome of Early Interventions to Prevent Posttraumatic Stress Disorder

J Clin Psychiatry 2016;77(5):e580-e587

Arieh Y. Shalev, MD ; Yael Ankri, MA ; Moran Gilad, MA ; Yossi Israeli-Shalev, MA ; Rhonda Adessky, PhD ; Meng Qian, PhD ; Sara Freedman, PhD

Article

Benzodiazepine Use and Risk of Mortality Among Patients With Schizophrenia: A Retrospective Longitudinal Study

J Clin Psychiatry 2016;77(5):661-667

Cynthia A. Fontanella, PhD ; John V. Campo, MD ; Gary S. Phillips, MAS ; Danielle L. Hiance-Steelesmith, MSW ; Helen Anne Sweeney, MS ; Kwok Tam, MS ; Douglas Lehrer, MD ; Robert Klein, PhD ; Mark Hurst, MD

Article

Introduction: Early Career Psychiatrists

J Clin Psychiatry 2016;77(5):672

Erika F. H. Saunders, MD

Article

Depressive Symptoms Following Stroke and Transient Ischemic Attack: Is It Time for a More Intensive Treatment Approach? Results From the TABASCO Cohort Study

J Clin Psychiatry 2016;77(5):673-680

Oren Tene, MD ; Shani Shenhar-Tsarfaty, PhD ; Amos D. Korczyn, MD ; Efrat Kliper, PhD ; Hen Hallevi, MD ; Ludmila Shopin, MD ; Eitan Auriel, MD ; Anat Mike, MA ; Natan M. Bornstein, MD ; Einor Ben Assayag, PhD

Article

Quantifying Intraindividual Variations in Plasma Clozapine Levels: A Population Pharmacokinetic Approach

J Clin Psychiatry 2016;77(5):681-687

Jimmy Lee, MBBS, MMED, MCI ; Robert Bies, PharmD, PhD ; Hiroyoshi Takeuchi, MD, PhD ; Gagan Fervaha, BSc ; Amaal Bhaloo, BMSc ; Valerie Powell, BScN ; Gary Remington, MD, PhD

Article

Clinical Outcomes Associated With Comorbid Posttraumatic Stress Disorder Among Patients With Bipolar Disorder

J Clin Psychiatry 2016;77(5):e555-e560

Ives C. Passos, MD, PhD ; Karen Jansen, PhD ; Taiane de A. Cardoso, PhD ; Gabriela D. Colpo, PhD ; Cristian P. Zeni, MD, PhD ; Joao Quevedo, MD, PhD ; Márcia Kauer-Sant' Anna, MD, PhD ; Giovanna Zunta-Soares, MD ; Jair C. Soares, MD, PhD ; Flavio Kapczinski, MD, PhD

Article

Doxazosin XL Reduces Symptoms of Posttraumatic Stress Disorder in Veterans With PTSD: A Pilot Clinical Trial

J Clin Psychiatry 2016;77(5):e561-e565

Christopher Rodgman, MD ; Christopher D. Verrico, PhD ; Manuela Holst, PhD ; Daisy Thompson-Lake, MA ; Colin N. Haile, PhD ; Richard De La Garza, II, PhD ; Murray A. Raskind, MD ; Thomas F. Newton, MD

Commentary

How Many Treatments Before Clozapine? Medication Choices Across the Spectrum of Treatment Resistance in Schizophrenia

J Clin Psychiatry 2016;77(5):e594-e596

Peter J. Weiden, MD

Commentary

The Incidence of Seizures With Antipsychotics

J Clin Psychiatry 2016;77(5):e590

John M. Davis, MD

Commentary

Can Development of PTSD Be Prevented After Acute Trauma?

J Clin Psychiatry 2016;77(5):e588-e589

Barbara Milrod, MD

Commentary

Benzodiazepine Safety: Mortality Risk or Multiple Chronic Disease Comorbidity?

J Clin Psychiatry 2016;77(5):e591-e593

Robert A. Rosenheck, MD ; Mehmet Sofuoglu, MD, PhD

Clinical and Practical Psychopharmacology

Cannabis and Neuropsychiatry, 1: Benefits and Risks

J Clin Psychiatry 2016;77(5):e551-e554

Chittaranjan Andrade, MD

Letter to the Editor

Open-Label Trial on the Effects of Memantine in Adults With Obsessive-Compulsive Disorder After a Single Ketamine Infusion

J Clin Psychiatry 2016;77(5):688-689

Carolyn I. Rodriguez, MD, PhD ; Amanda Levinson, BS ; Jordana Zwerling, MA ; Donna Vermes, PMHNPd ; Helen Blair Simpson, MD, PhD

Letter to the Editor

Safety and Efficacy of Electroconvulsive Therapy for Depression in the Presence of Deep Brain Stimulation in Obsessive-Compulsive Disorder

J Clin Psychiatry 2016;77(5):689-690

David L. Rosenthal, BA ; Evan Leibu, MD ; Amy S. Aloysi, MD, MPH ; Brian H. Kopell, MD ; Wayne K. Goodman, MD ; Charles H. Kellner, MD

Letter to the Editor

Gene Expression Profiling of the xMHC Region Reveals 9 Candidate Genes in Schizophrenia

J Clin Psychiatry 2016;77(5):e597-e599

Liya Sun, PhD ; Ying Qing, BS ; Xuhan Yang, BS ; Chao Yang, PhD ; Jie Jiang, BS ; Xiaowen Hu, BS ; Jingyan Ding, MS ; Lin He, PhD ; Liwen Tan, PhD ; Chunling Wan, PhD

Letter to the Editor

Sudden Cardiac Death Related to Antipsychotics: Beyond the Long QT Syndrome Hypothesis

J Clin Psychiatry 2016;77(5):e600

Tiziano Acciavatti, MD ; Giovanni Martinotti, MD, PhD ; Massimo di Giannantonio, MD

Educational Activity

Why Is Mechanism of Action Important in Antidepressant Treatment?

J Clin Psychiatry 2016;77(5):e603

Thomas L. Schwartz, MD

Educational Activity

Impact of Anxious Symptoms and Comorbid Anxiety Disorders on Functional Impairment in Depressed Patients

J Clin Psychiatry 2016;77(5):e604

Larry Culpepper, MD, MPH

Book Review

Green's Child and Adolescent Clinical Psychopharmacology, 5th ed

J Clin Psychiatry 2016;77(5):e601

Robert L. Findling, MD, MBA

Book Review

The Social Determinants of Mental Health

J Clin Psychiatry 2016;77(5):e602

Jeffrey Stovall, MD

Volume 77 • 2016 • 5

Meta-Analysis

Early Onset of Response With Selective Serotonin Reuptake Inhibitors in Obsessive-Compulsive Disorder: A Meta-Analysis

Demographic Variables, Design Characteristics, and Effect Sizes of Randomized, Placebo-Controlled, Monotherapy Trials of Major Depressive Disorder and Bipolar Depression

Original Research

Clozapine and Risperidone in Moderately Refractory Schizophrenia: A 6-Month Randomized Double-Blind Comparison

Efficacy Outcomes From 3 Clinical Trials of Edivoxetine as Adjunctive Treatment for Patients With Major Depressive Disorder Who Are Partial Responders to Selective Serotonin Reuptake Inhibitor Treatment

The Course of Suicide Risk Following Traumatic Injury

Long-Term Efficacy, Safety, and Tolerability of l-Methylfolate Calcium 15 mg as Adjunctive Therapy With Selective Serotonin Reuptake Inhibitors: A 12-Month, Open-Label Study Following a Placebo-Controlled #05#

Correlation of Clinical Response With Homocysteine Reduction During Therapy With Reduced B Vitamins in Patients With MDD Who Are Positive for MTHFR C677T or A1298C Polymorphism: A Randomized, Double-Blind, Placebo-Controlled Study

Age at the Time of Exposure to Trauma Modulates the Psychopathological Profile in Patients With Early Psychosis

Adherence to Antidepressants Is Associated With Lower Mortality: A 4-Year Population-Based Cohort Study

Comparative Risk of Seizure With Use of First- and Second-Generation Antipsychotics in Patients With Schizophrenia and Mood Disorders

Long-Term Outcome of Early Interventions to Prevent Posttraumatic Stress Disorder

Article

Benzodiazepine Use and Risk of Mortality Among Patients With Schizophrenia: A Retrospective Longitudinal Study

Introduction: Early Career Psychiatrists

Depressive Symptoms Following Stroke and Transient Ischemic Attack: Is It Time for a More Intensive Treatment Approach? Results From the TABASCO Cohort Study

Quantifying Intraindividual Variations in Plasma Clozapine Levels: A Population Pharmacokinetic Approach

Clinical Outcomes Associated With Comorbid Posttraumatic Stress Disorder Among Patients With Bipolar Disorder

Doxazosin XL Reduces Symptoms of Posttraumatic Stress Disorder in Veterans With PTSD: A Pilot Clinical Trial

Commentary

How Many Treatments Before Clozapine? Medication Choices Across the Spectrum of Treatment Resistance in Schizophrenia

The Incidence of Seizures With Antipsychotics

Can Development of PTSD Be Prevented After Acute Trauma?

Benzodiazepine Safety: Mortality Risk or Multiple Chronic Disease Comorbidity?

Clinical and Practical Psychopharmacology

Cannabis and Neuropsychiatry, 1: Benefits and Risks

Letter to the Editor

Open-Label Trial on the Effects of Memantine in Adults With Obsessive-Compulsive Disorder After a Single Ketamine Infusion

Safety and Efficacy of Electroconvulsive Therapy for Depression in the Presence of Deep Brain Stimulation in Obsessive-Compulsive Disorder

Gene Expression Profiling of the xMHC Region Reveals 9 Candidate Genes in Schizophrenia

Sudden Cardiac Death Related to Antipsychotics: Beyond the Long QT Syndrome Hypothesis

Educational Activity

Why Is Mechanism of Action Important in Antidepressant Treatment?

Impact of Anxious Symptoms and Comorbid Anxiety Disorders on Functional Impairment in Depressed Patients

Book Review

Green's Child and Adolescent Clinical Psychopharmacology, 5th ed

The Social Determinants of Mental Health

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