The Journal of
Clinical Psychiatry

Volume 83 • 2022 • 3

Original Research

Electroconvulsive Therapy and Death by Suicide

J Clin Psychiatry 2022;83(3):21m13886

Bradley V. Watts, MD, MPH^a,b ; Talya Peltzman, MPH^b ; Brian Shiner, MD, MPH^a,b

Original Research

Phase 3b Multicenter, Prospective, Open-label Trial to Evaluate the Effects of a Digital Medicine System on Inpatient Psychiatric Hospitalization Rates for Adults With Schizophrenia

J Clin Psychiatry 2022;83(3):21m14132

Elan A. Cohen, PhD ; Taisa Skubiak, MBA ; Dusica Hadzi Boskovic, MS ; Keinya Norman, MS ; Jonathan Knights, PhD ; Hui Fang, PhD ; Antonia Coppin-Renz, MD ; Timothy Peters-Strickland, MD ; Jean-Pierre Lindenmayer, MD ; J. Corey Reuteman-Fowler, PhD

Original Research

Increased Admissions of Older Adults to Substance Use Treatment Facilities and Associated Changes in Admission Characteristics, 2000–2017

J Clin Psychiatry 2022;83(3):21m13938

Peter Jongho Na, MD, MPH^a,b ; Robert Rosenheck, MD^a,c ; Taeho Greg Rhee, PhD^a,c,d

Original Research

Randomized, Placebo-Controlled Effectiveness Study of Quetiapine XR in Comorbid Depressive and Anxiety Disorders

J Clin Psychiatry 2022;83(3):21m14096

Nisha Ravindran, MD^a,b ; Martha McKay, PhD^c ; Angela Paric, PhD^a,b ; Sunny Johnson, MD^d ; Ranjith Chandrasena, MD^e ; Gaby Abraham, MD^a ; Arun V. Ravindran, MD, PhD^a,b

Original Research

Influence of Care Delivery Models on Quality of Diabetes Care Among Individuals With Schizophrenia

J Clin Psychiatry 2022;83(3):21m13880

Nicole Huang, PhD^a,b ; Po-Sen Wang, MS^b ; Chuan-Yu Chen, PhD^b ; Ya-Mei Bai, MD, PhD^c,d ; Yiing-Jenq Chou, MD, PhD^b,e

Original Research

Suicide Risk in a National VA Sample: Roles of Psychiatric Diagnosis, Behavior Regulation, Substance Use, and Smoking

J Clin Psychiatry 2022;83(3):21m14123

Alan C. Swann, MD^a,b,* ; David P. Graham, MD^a,b ; Anna V. Wilkinson, PhD^c ; Thomas R. Kosten, MD^a,b

Original Research

Deimplementation of Benzodiazepine Prescribing in Posttraumatic Stress Disorder in the Veterans Health Administration

J Clin Psychiatry 2022;83(3):21m14128

Nancy C. Bernardy, PhD^a ; Matthew J. Friedman, MD, PhD^a ; Brian C. Lund, PharmD, MS^b

Original Research

Antipsychotic Efficacy of KarXT (Xanomeline−Trospium): Post Hoc Analysis of Positive and Negative Syndrome Scale Categorical Response Rates, Time Course of Response, and Symptom Domains of Response in a Phase 2 Study

J Clin Psychiatry 2022;83(3):21m14316

Peter J. Weiden, MD^a ; Alan Breier, MD^b ; Sarah Kavanagh, MPH^c ; Andrew C. Miller, PhD^a ; Stephen K. Brannan, MD^a ; Steven M. Paul, MD^a

Original Research

Economic Burden of Commercially Insured Patients With Major Depressive Disorder and Acute Suicidal Ideation or Behavior in the United States

J Clin Psychiatry 2022;83(3):21m14090

Dominic Pilon, MA ; Cheryl Neslusan, PhD ; Maryia Zhdanava, MA^* ; John J. Sheehan, PhD ; Kruti Joshi, MPH ; Laura Morrison, MScPH ; Carmine Rossi, PhD ; Patrick Lefebvre, MA ; Paul E. Greenberg, MS^c

Original Research

The Economic Burden of Posttraumatic Stress Disorder in the United States From a Societal Perspective

J Clin Psychiatry 2022;83(3):21m14116

Lori L. Davis, MD^a,b,* ; Jeff Schein, DrPH, MPH^c ; Martin Cloutier, MSc^d ; Patrick Gagnon-Sanschagrin, MSc^d ; Jessica Maitland, MScPH^d ; Annette Urganus, MPH^e ; Annie Guerin, MSc^d ; Patrick Lefebvre, MA^d ; Christy R. Houle, PhD, MPH^e

Original Research

Early Antidepressant Resistance in Late-Onset Major Depressive Disorder: A Nationwide Population-Based Cohort Study

J Clin Psychiatry 2022;83(3):21m14073

Po-Chun Lin, MD^a ; Ta-Chuan Yeh, MD^b ; Ya-Mei Bai, MD, PhD^c,d ; Ju-Wei Hsu, MD^c,d ; Kai-Lin Huang, MD^c,d ; Nai-Ying Ko, PhD^e ; Che-Sheng Chu, MD^f,g ; Hsuan-Te Chu, MD^a ; Shih-Jen Tsai, MD^c,d ; Tzeng-Ji Chen, MD; PhD^h,i ; Chih-Sung Liang, MD^a,j ; Mu-Hong Chen, MD^c,d

Original Research

Impact of Depression on Anxiety, Well-being, and Suicidality in Mexican Adolescent and Young Adult Students From Mexico City: A Mental Health Screening Using Smartphones

J Clin Psychiatry 2022;83(3):20m13806

Ismael Martínez-Nicolás, PhD^a,‡ ; Pavel E. Arenas Castañeda, MD^b,‡ ; Cristian Antonio Molina-Pizarro, MD^c ; Arsenio Rosado Franco, MD^c ; Cynthya Maya-Hernández, PhD^d ; Igor Barahona, PhD^e ; Gonzalo Martínez-Alés, MD, PhD^f ; Fuensanta Aroca Bisquert, PhD^e,g ; Enrique Baca-García, MD, PhD^{h,i,j,k,l,m,n,o,*} ; María Luisa Barrigón, MD, PhD^h,i

Original Research

Prevalence, Clinical Correlates, Cognitive Trajectories, and Dementia Risk Associated With Mild Behavioral Impairment in Asians

J Clin Psychiatry 2022;83(3):21m14105

Cheuk Ni Kan, PDipPsych^a ; Jemellee Cano, MD^b ; Xuhao Zhao, MPH^c ; Zahinoor Ismail, MD^d ; Christopher Li-Hsian Chen, FRCP^a,e ; Xin Xu, PhD^a,c

Original Research

Antipsychotic Exposure in Clinical High Risk of Psychosis: Empirical Insights From a Large Cohort Study

J Clin Psychiatry 2022;83(3):21m14092

JiaHui Zeng, MD^a ; Andrea Raballo, PhD^b,c ; RanPiao Gan, MD^a ; GuiSen Wu, MD^a ; YanYan Wei, PhD^a ; LiHua Xu, PhD^a ; XiaoChen Tang, PhD^a ; YeGang Hu, PhD^a ; YingYing Tang, PhD^a ; Tao Chen, PhD^d,e ; ChunBo Li, PhD^a ; JiJun Wang, PhD^a,f,g,‡ ; TianHong Zhang, MD, PhD^a,

Original Research

Identifying Pediatric Mood Disorders From Transdiagnostic Polygenic Risk Scores: A Study of Children and Adolescents

J Clin Psychiatry 2022;83(3):21m14180

Eric J. Barnett, BSc^a ; Joseph Biederman, MD^b,c ; Alysa E. Doyle, PhD^c,d ; Jonathan Hess, PhD^e ; Maura DiSalvo, MPH^b ; Stephen V. Faraone, PhD^a,e

Original Research

Co-occurring Depression and Suicidal Ideation in Opioid Use Disorder: Prevalence and Response During Treatment With Buprenorphine-Naloxone and Injection Naltrexone

J Clin Psychiatry 2022;83(3):21m14140

Peter J. Na, MD, MPH^a,b,c ; Jennifer Scodes, MS^d ; Marc Fishman, MD^e,f ; John Rotrosen, MD^a ; Edward V. Nunes Jr, MD^d,g

Original Research

Resting State MRI Amplitude of Low Frequency Fluctuations Associated With Suicidal Ideation in Bipolar Depression

J Clin Psychiatry 2022;83(3):21m14054

Martin J. Lan, MD, PhD^a,b,* ; Spiro P. Pantazatos, PhD^a,b ; R. Todd Ogden, PhD^a,b ; Harry Rubin-Falcone, BS^a,b ; David Hellerstein, MD^a,c ; Patrick J. McGrath, MD^a,c ; J. John Mann, MD^a,b,d

Original Research

Subthreshold Change in Glycated Hemoglobin and Body Mass Index After the Initiation of Second-Generation Antipsychotics Among Patients With Schizophrenia or Bipolar Disorder: A Nationwide Prospective Cohort Study in Japan

J Clin Psychiatry 2022;83(3):21m14099

Ryo Sawagashira, MD^a,b ; Ryodai Yamamura, PhD^c ; Ryo Okubo, PhD, MD^d,* ; Naoki Hashimoto, PhD, MD^a ; Shuhei Ishikawa, PhD^e ; Yoichi M. Ito, PhD^f ; Norihiro Sato, PhD, MD^f ; Ichiro Kusumi, PhD, MD^a

Original Research

Epilepsy and Associated Factors Among Adults Hospitalized for Attempted Suicide

J Clin Psychiatry 2022;83(3):21m14207

Basma Akrout Brizard, MSc^a ; Philippe Courtet, MD, PhD^b,c ; Isabelle Jaussent, PhD^d ; Jorge Lopez-Castroman, MD, PhD^c,e ; Marion Leboyer, MD, PhD^f,g ; Carolina Baeza-Velasco, MSc, PhD^a,b,c

Original Research

Association Between Receipt of Antidepressants and Retention in Buprenorphine Treatment for Opioid Use Disorder: A Population-Based Retrospective Cohort Study

J Clin Psychiatry 2022;83(3):21m14001

Kun Zhang, PhD^a ; Christopher M. Jones, PharmD, DrPH^a ; Wilson M. Compton, MD, MPE^b ; Gery P. Guy, PhD, MPH^a ; Mary E. Evans, MD^a ; Nora D. Volkow, MD^b

Commentary

What Is the Role of Digital Medicine for Adherence Monitoring in Patients With Serious Mental Illness?

J Clin Psychiatry 2022;83(3):22com14443

Oliver Freudenreich, MD, FACLP^a,b

Clinical and Practical Psychopharmacology

Antidepressant Drugs and Health-Related Quality of Life: A Reader’s Guide on How to Examine a “Viral” Research Paper With a Critical Eye

J Clin Psychiatry 2022;83(3):22f14527

Chittaranjan Andrade, MD

Clinical and Practical Psychopharmacology

Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Other Neurodevelopmental Outcomes Associated With Antipsychotic Drug Exposure During Pregnancy

J Clin Psychiatry 2022;83(3):22f14529

Chittaranjan Andrade, MD

ASCP Corner

Prioritizing Patient Preferences: A Practical Guide for Tailoring Treatment Choices in Interventional Psychiatry

J Clin Psychiatry 2022;83(3):22ac14436

Joshua Berman, MD, PhD^a,* ; Adrian Jacques Ambrose, MD, MPH^a

Letter to the Editor

Twelve-Month Outcomes for Remitters Following Electroconvulsive Therapy for Depression

J Clin Psychiatry 2022;83(3):21lr14371

Ana Jelovac, PhD^a ; Declan M. McLoughlin, PhD^a,b

Letter to the Editor

Research Design and Overfitting: Reply to Jelovac and McLoughlin

J Clin Psychiatry 2022;83(3):21lr14371a

Chittaranjan Andrade, MD

Letter to the Editor

Peer-Led Psychotherapy: The Time Is Now

J Clin Psychiatry 2022;83(3):21lr14366a

Lianne M. Tomfohr-Madsen, PhD^a ; Leslie E. Roos, PhD^b ; Joshua W. Madsen, PhD^c ; Jennifer Leason, PhD^d ; Daisy R. Singla, PhD^e,f,g ; Jaime Charlebois, MScN^g ; Patricia Tomasi, BJour^h ; Kathleen H. Chaput, PhDⁱ

Letter to the Editor

Peer-Delivered Psychotherapy for Postpartum Depression: Has Its Time Come? Not Yet—Reply to Tomfohr-Madsen et al

J Clin Psychiatry 2022;83(3):21lr14366a

Michael W. O’Hara, PhD

Letter to the Editor

Corrigendum to “Decreases in Suicidality Following Psychedelic Therapy: A Meta-Analysis of Individual Patient Data Across Clinical Trials”

J Clin Psychiatry 2022;83(3):22l14505

Richard J. Zeifman, MA^a,b ; Dengdeng Yu, PhD^c ; Nikhita Singhal, MD^d ; Guan Wang, HBSc^e ; Sandeep M. Nayak, MD^f ; Cory R. Weissman, MD^g

Volume 83 • 2022 • 3

Original Research

Electroconvulsive Therapy and Death by Suicide

Phase 3b Multicenter, Prospective, Open-label Trial to Evaluate the Effects of a Digital Medicine System on Inpatient Psychiatric Hospitalization Rates for Adults With Schizophrenia

Increased Admissions of Older Adults to Substance Use Treatment Facilities and Associated Changes in Admission Characteristics, 2000–2017

Randomized, Placebo-Controlled Effectiveness Study of Quetiapine XR in Comorbid Depressive and Anxiety Disorders

Influence of Care Delivery Models on Quality of Diabetes Care Among Individuals With Schizophrenia

Suicide Risk in a National VA Sample: Roles of Psychiatric Diagnosis, Behavior Regulation, Substance Use, and Smoking

Deimplementation of Benzodiazepine Prescribing in Posttraumatic Stress Disorder in the Veterans Health Administration

Antipsychotic Efficacy of KarXT (Xanomeline−Trospium): Post Hoc Analysis of Positive and Negative Syndrome Scale Categorical Response Rates, Time Course of Response, and Symptom Domains of Response in a Phase 2 Study

Economic Burden of Commercially Insured Patients With Major Depressive Disorder and Acute Suicidal Ideation or Behavior in the United States

The Economic Burden of Posttraumatic Stress Disorder in the United States From a Societal Perspective

Early Antidepressant Resistance in Late-Onset Major Depressive Disorder: A Nationwide Population-Based Cohort Study

Impact of Depression on Anxiety, Well-being, and Suicidality in Mexican Adolescent and Young Adult Students From Mexico City: A Mental Health Screening Using Smartphones

Prevalence, Clinical Correlates, Cognitive Trajectories, and Dementia Risk Associated With Mild Behavioral Impairment in Asians

Antipsychotic Exposure in Clinical High Risk of Psychosis: Empirical Insights From a Large Cohort Study

Identifying Pediatric Mood Disorders From Transdiagnostic Polygenic Risk Scores: A Study of Children and Adolescents

Co-occurring Depression and Suicidal Ideation in Opioid Use Disorder: Prevalence and Response During Treatment With Buprenorphine-Naloxone and Injection Naltrexone

Resting State MRI Amplitude of Low Frequency Fluctuations Associated With Suicidal Ideation in Bipolar Depression

Subthreshold Change in Glycated Hemoglobin and Body Mass Index After the Initiation of Second-Generation Antipsychotics Among Patients With Schizophrenia or Bipolar Disorder: A Nationwide Prospective Cohort Study in Japan

Epilepsy and Associated Factors Among Adults Hospitalized for Attempted Suicide

Association Between Receipt of Antidepressants and Retention in Buprenorphine Treatment for Opioid Use Disorder: A Population-Based Retrospective Cohort Study

Commentary

What Is the Role of Digital Medicine for Adherence Monitoring in Patients With Serious Mental Illness?

Clinical and Practical Psychopharmacology

Antidepressant Drugs and Health-Related Quality of Life: A Reader’s Guide on How to Examine a “Viral” Research Paper With a Critical Eye

Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Other Neurodevelopmental Outcomes Associated With Antipsychotic Drug Exposure During Pregnancy

ASCP Corner

Prioritizing Patient Preferences: A Practical Guide for Tailoring Treatment Choices in Interventional Psychiatry

Letter to the Editor

Twelve-Month Outcomes for Remitters Following Electroconvulsive Therapy for Depression

Research Design and Overfitting: Reply to Jelovac and McLoughlin

Peer-Led Psychotherapy: The Time Is Now

Peer-Delivered Psychotherapy for Postpartum Depression: Has Its Time Come? Not Yet—Reply to Tomfohr-Madsen et al

Corrigendum to “Decreases in Suicidality Following Psychedelic Therapy: A Meta-Analysis of Individual Patient Data Across Clinical Trials”

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Volume 83 • 2022 • 3

Original Research

Electroconvulsive Therapy and Death by Suicide

Phase 3b Multicenter, Prospective, Open-label Trial to Evaluate the Effects of a Digital Medicine System on Inpatient Psychiatric Hospitalization Rates for Adults With Schizophrenia

Increased Admissions of Older Adults to Substance Use Treatment Facilities and Associated Changes in Admission Characteristics, 2000–2017

Randomized, Placebo-Controlled Effectiveness Study of Quetiapine XR in Comorbid Depressive and Anxiety Disorders

Influence of Care Delivery Models on Quality of Diabetes Care Among Individuals With Schizophrenia

Suicide Risk in a National VA Sample: Roles of Psychiatric Diagnosis, Behavior Regulation, Substance Use, and Smoking

Deimplementation of Benzodiazepine Prescribing in Posttraumatic Stress Disorder in the Veterans Health Administration

Antipsychotic Efficacy of KarXT (Xanomeline−Trospium): Post Hoc Analysis of Positive and Negative Syndrome Scale Categorical Response Rates, Time Course of Response, and Symptom Domains of Response in a Phase 2 Study

Economic Burden of Commercially Insured Patients With Major Depressive Disorder and Acute Suicidal Ideation or Behavior in the United States

The Economic Burden of Posttraumatic Stress Disorder in the United States From a Societal Perspective

Early Antidepressant Resistance in Late-Onset Major Depressive Disorder: A Nationwide Population-Based Cohort Study

Impact of Depression on Anxiety, Well-being, and Suicidality in Mexican Adolescent and Young Adult Students From Mexico City: A Mental Health Screening Using Smartphones

Prevalence, Clinical Correlates, Cognitive Trajectories, and Dementia Risk Associated With Mild Behavioral Impairment in Asians

Antipsychotic Exposure in Clinical High Risk of Psychosis: Empirical Insights From a Large Cohort Study

Identifying Pediatric Mood Disorders From Transdiagnostic Polygenic Risk Scores: A Study of Children and Adolescents

Co-occurring Depression and Suicidal Ideation in Opioid Use Disorder: Prevalence and Response During Treatment With Buprenorphine-Naloxone and Injection Naltrexone

Resting State MRI Amplitude of Low Frequency Fluctuations Associated With Suicidal Ideation in Bipolar Depression

Subthreshold Change in Glycated Hemoglobin and Body Mass Index After the Initiation of Second-Generation Antipsychotics Among Patients With Schizophrenia or Bipolar Disorder: A Nationwide Prospective Cohort Study in Japan

Epilepsy and Associated Factors Among Adults Hospitalized for Attempted Suicide

Association Between Receipt of Antidepressants and Retention in Buprenorphine Treatment for Opioid Use Disorder: A Population-Based Retrospective Cohort Study

Commentary

What Is the Role of Digital Medicine for Adherence Monitoring in Patients With Serious Mental Illness?

Clinical and Practical Psychopharmacology

Antidepressant Drugs and Health-Related Quality of Life: A Reader’s Guide on How to Examine a “Viral” Research Paper With a Critical Eye

Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Other Neurodevelopmental Outcomes Associated With Antipsychotic Drug Exposure During Pregnancy

ASCP Corner

Prioritizing Patient Preferences: A Practical Guide for Tailoring Treatment Choices in Interventional Psychiatry

Letter to the Editor

Twelve-Month Outcomes for Remitters Following Electroconvulsive Therapy for Depression

Research Design and Overfitting: Reply to Jelovac and McLoughlin

Peer-Led Psychotherapy: The Time Is Now

Peer-Delivered Psychotherapy for Postpartum Depression: Has Its Time Come? Not Yet—Reply to Tomfohr-Madsen et al

Corrigendum to “Decreases in Suicidality Following Psychedelic Therapy: A Meta-Analysis of Individual Patient Data Across Clinical Trials”

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