The Journal of
Clinical Psychiatry

Volume 84 • 2023 • 3

Editorial

JCP’s New Look

J Clin Psychiatry 2023;84(3):23ed14949

Marlene P. Freeman, MD

In Memoriam

In Memoriam: Robert M. A. Hirschfeld, MD, 1943–2023

J Clin Psychiatry 2023;84(3):23f14847

Joseph F. Goldberg, MD

Narrative Review

Beyond “Psychotropic”: Repurposing Psychiatric Drugs for COVID-19, Alzheimer’s Disease, and Cancer

J Clin Psychiatry 2023;84(3):22r14494

Eric J. Lenze, MD; Angela M. Reiersen, MD; Charles F. Zorumski, MD; Paramala J. Santosh, FRCPsych

Meta-Analysis

The Neuropsychological Mechanisms of Treatment of Bipolar Disorder and Borderline Personality Disorder: Activation Likelihood Estimation Meta-Analysis of Brain Imaging Research

J Clin Psychiatry 2023;84(3):22r14463

Jingyi Luo, MSc; Meng Liang, MSc; Pengcheng Yi, PhD; Xiaoming Li, PhD

Systematic Review

Control Conditions in Randomized Trials of Psychedelics: An ACTTION Systematic Review

J Clin Psychiatry 2023;84(3):22r14518

Sandeep M. Nayak, MD; Melissa K. Bradley, BA; Bethea A. Kleykamp, PhD; Eric C. Strain, MD; Robert H. Dworkin, PhD; Matthew W. Johnson, PhD

Original Research

The Protective Effect of Clozapine on Suicide: A Population Mortality Study of Statewide Autopsy Records in Maryland

J Clin Psychiatry 2023;84(3):22m14587

Brian J. Lee, MD, PhD; Robert O. Cotes, MD; Ramin Mojtabai, MD, PhD; Russell L. Margolis, MD; Frederick C. Nucifora, Jr, DO, PhD; Paul S. Nestadt, MD

Original Research

Olanzapine/Samidorphan in Young Adults With Schizophrenia, Schizophreniform Disorder, or Bipolar I Disorder Who Are Early in Their Illness: Results of the Randomized, Controlled ENLIGHTEN-Early Study

J Clin Psychiatry 2023;84(3):22m14674

René S. Kahn, MD, PhD; John M. Kane, MD; Christoph U. Correll, MD; Christina Arevalo, MS; Adam Simmons, MPH; Christine Graham, PhD; Sergey Yagoda, MD, PhD; Beibei Hu, MS; David McDonnell, MD

Original Research

The Efficacy of Lumateperone in Patients With Bipolar Depression With Mixed Features

J Clin Psychiatry 2023;84(3):22m14739

Roger S. McIntyre, MD; Suresh Durgam, MD; Jason Huo, PhD; Susan G. Kozauer, MD; Stephen M. Stahl, MD, PhD

Original Research

Impact of the Abbreviated Suicide Crisis Syndrome Checklist on Clinical Decision Making in the Emergency Department

J Clin Psychiatry 2023;84(3):22m14655

Ethan Karsen, MD; Lisa J. Cohen, PhD; Betsy White, LCSW; Gabriele P. De Luca, MD; Inna Goncearenco; Igor I. Galynker, MD; Frederick E. Miller, MD, PhD

Original Research

Treatment Journey From Diagnosis to the Successful Implementation of a Long-Acting Injectable Antipsychotic Agent in Young Adults With Schizophrenia

J Clin Psychiatry 2023;84(3):22m14544

John M. Kane, MD; Marko A. Mychaskiw, PhD; Sangtaeck Lim, MPH; Mark Suett, MD; Marc Tian, PhD; Jose M. Rubio, MD

Original Research

Generalizability of the Results of Efficacy Trials in First-Episode Schizophrenia: Comparing Outcome and Study Discontinuation of Groups of Participants in the Optimization of Treatment and Management of Schizophrenia in Europe (OPTiMiSE) Trial

J Clin Psychiatry 2023;84(3):22m14531

Lyliana G. Nasib, PhD; Inge Winter-van Rossum, PhD; Nicolaas P. A. Zuithoff, PhD; Zimbo S. R. M. Boudewijns, PhD; Stefan Leucht, MD, PhD; René S. Kahn, MD, PhD

Original Research

Interpersonal Trauma and Depression Severity Among Individuals With Bipolar Disorder: Findings From the Prechter Longitudinal Study of Bipolar Disorder

J Clin Psychiatry 2023;84(3):22m14434

Anna L. Wrobel, PhD; Samantha E. Russell, BHealth&MedSc(Hons); Anuradhi Jayasinghe, MA; Mojtaba Lotfaliany, PhD; Alyna Turner, PhD; Olivia M. Dean, PhD; Sue M. Cotton, PhD; Claudia Diaz-Byrd, MS; Anastasia K. Yocum, PhD; Elizabeth R. Duval, PhD; Tobin J. Ehrlich, PhD; David F. Marshall, PhD; Michael Berk, MD; Melvin G. McInnis, MD

Original Research

Pandemics and Suicide Rates in Spain: From the Spanish Flu to COVID-19

J Clin Psychiatry 2023;84(3):22m14601

Sergio Sanz-Gómez, MSc; Adrián Alacreu-Crespo, Prof; Ana Fructuoso, PhD; María Isabel Perea-González, MSc; Julio Antonio Guija, MD; Lucas Giner, Prof, MD

Original Research

50% Improvement: Should Treatment Response Go Beyond Symptom Improvement When Evaluating the Treatment of Depression?

J Clin Psychiatry 2023;84(3):22m14706

Mark Zimmerman, MD; Sin-Ying Lin, PhD

Original Research

Pregnancy-Specific Anxiety Tool (PSAT): Instrument Development and Psychometric Evaluation

J Clin Psychiatry 2023;84(3):22m14696

Hamideh Bayrampour, MSc, PhD; Richard E. Hohn, PhD(c); Sukhpreet K. Tamana, PhD; Richard Sawatzky, PhD; Patricia A. Janssen, RN, PhD; Jeffrey N. Bone, PhD(c); Nichole Fairbrother, PhD; K. S. Joseph, MD, PhD

Original Research

Endothelial Function in Youth With Bipolar Disorder: Preliminary Evidence for Mood Polarity Differences

J Clin Psychiatry 2023;84(3):22m14608

Kody G. Kennedy, PhD; Sudhir Karthikeyan, MSc; Alysha A. Sultan, PhD; Brian W. McCrindle, MD, MPH; Gregory E. Miller, PhD; Benjamin I. Goldstein, MD, PhD

Original Research

Lower Ghrelin Levels Are Associated With Higher Anxiety Symptoms in Adolescents and Young Adults With Avoidant/Restrictive Food Intake Disorder

J Clin Psychiatry 2023;84(3):22m14482

Aluma Chovel Sella, MD; Natalia Hadaway, BS; Casey Stern, BS; Kendra R. Becker, PhD; Laura M. Holsen, PhD; Kamryn T. Eddy, PhD; Nadia Micali, MD, PhD; Madhusmita Misra, MD, MPH; Jennifer J. Thomas, PhD; Elizabeth A. Lawson, MD, MMSc

Original Research

Enhanced Primary Care for People With Serious Mental Illness: A Propensity Weighted Cohort Study

J Clin Psychiatry 2023;84(3):22m14496

Alex K. Gertner, MD, PhD; Lexie R. Grove, PhD, MSPH; Karen E. Swietek, PhD; Ching-Ching Claire Lin, PhD; Neepa Ray, MS; Tyler L. Malone, MS; David L. Rosen, MD, PhD; Theodore R. Zarzar, MD; Marisa Elena Domino, PhD; Beat D. Steiner, MD, MPH

Original Research

Impact of Tardive Dyskinesia on Physical, Psychological, Social, and Professional Domains of Patient Lives: A Survey of Patients in the United States

J Clin Psychiatry 2023;84(3):22m14694

Rakesh Jain, MD, MPH; Rajeev Ayyagari, PhD; Debbie Goldschmidt, PhD; Mo Zhou, PhD; Stacy Finkbeiner, PhD; Sam Leo, PharmD

Cross Talk: Case Conferences From MGH

Pharmacotherapy and Ketamine Assisted Psychotherapy for Treatment-Resistant Depression: A Patient With Lifelong Self-Doubt and Self-Criticism

J Clin Psychiatry 2023;84(3):23ct14798

Albert Yeung, MD, ScD; Guy Sapirstein, PhD; Laura D. Crain, MD; Margaret A. Cramer, PhD, ABPP; Fernando Espi Forcen, MD, PhD; Susan Sprich, PhD; Jonah N. Cohen, PhD

Brief Report

Depressive Symptomatology Is Associated With Smaller Reductions in Drug Cue Reactivity During Extended-Release Naltrexone Treatment of Opioid Use Disorder

J Clin Psychiatry 2023;84(3):22br14567

Zhenhao Shi, PhD; Xinyi Li, PhD; Kyle M. Kampman, MD; Anna Rose Childress, PhD; Corinde E. Wiers, PhD; Daniel D. Langleben, MD

Commentary

Repetitive Transcranial Magnetic Stimulation for Treatment-Resistant Depression: Mismatch of Evidence and Insurance Coverage Policies in the United States

J Clin Psychiatry 2023;84(3):22com14575

Cory R. Weissman, MD; Richard A. Bermudes, MD; Jeffrey Voigt, MBA, MPH; Conor Liston, MD, PhD; Nolan Williams, MD; Daniel M. Blumberger, MD, MSc; Paul B. Fitzgerald, MD, PhD; Zafiris J. Daskalakis, MD, PhD

Clinical and Practical Psychopharmacology

How to Understand the 95% Confidence Interval Around the Relative Risk, Odds Ratio, and Hazard Ratio: As Simple as It Gets

J Clin Psychiatry 2023;84(3):23f14933

Chittaranjan Andrade, MD

Clinical and Practical Psychopharmacology

Understanding Misunderstandings About the Relative Risk and Odds Ratio

J Clin Psychiatry. 2023;84(3):23f14943

Chittaranjan Andrade, MD

Volume 84 • 2023 • 3

Editorial

JCP’s New Look

In Memoriam

In Memoriam: Robert M. A. Hirschfeld, MD, 1943–2023

Narrative Review

Beyond “Psychotropic”: Repurposing Psychiatric Drugs for COVID-19, Alzheimer’s Disease, and Cancer

Meta-Analysis

The Neuropsychological Mechanisms of Treatment of Bipolar Disorder and Borderline Personality Disorder: Activation Likelihood Estimation Meta-Analysis of Brain Imaging Research

Systematic Review

Control Conditions in Randomized Trials of Psychedelics: An ACTTION Systematic Review

Original Research

The Protective Effect of Clozapine on Suicide: A Population Mortality Study of Statewide Autopsy Records in Maryland

Olanzapine/Samidorphan in Young Adults With Schizophrenia, Schizophreniform Disorder, or Bipolar I Disorder Who Are Early in Their Illness: Results of the Randomized, Controlled ENLIGHTEN-Early Study

The Efficacy of Lumateperone in Patients With Bipolar Depression With Mixed Features

Impact of the Abbreviated Suicide Crisis Syndrome Checklist on Clinical Decision Making in the Emergency Department

Treatment Journey From Diagnosis to the Successful Implementation of a Long-Acting Injectable Antipsychotic Agent in Young Adults With Schizophrenia

Generalizability of the Results of Efficacy Trials in First-Episode Schizophrenia: Comparing Outcome and Study Discontinuation of Groups of Participants in the Optimization of Treatment and Management of Schizophrenia in Europe (OPTiMiSE) Trial

Interpersonal Trauma and Depression Severity Among Individuals With Bipolar Disorder: Findings From the Prechter Longitudinal Study of Bipolar Disorder

Pandemics and Suicide Rates in Spain: From the Spanish Flu to COVID-19

50% Improvement: Should Treatment Response Go Beyond Symptom Improvement When Evaluating the Treatment of Depression?

Pregnancy-Specific Anxiety Tool (PSAT): Instrument Development and Psychometric Evaluation

Endothelial Function in Youth With Bipolar Disorder: Preliminary Evidence for Mood Polarity Differences

Lower Ghrelin Levels Are Associated With Higher Anxiety Symptoms in Adolescents and Young Adults With Avoidant/Restrictive Food Intake Disorder

Enhanced Primary Care for People With Serious Mental Illness: A Propensity Weighted Cohort Study

Impact of Tardive Dyskinesia on Physical, Psychological, Social, and Professional Domains of Patient Lives: A Survey of Patients in the United States

Cross Talk: Case Conferences From MGH

Pharmacotherapy and Ketamine Assisted Psychotherapy for Treatment-Resistant Depression: A Patient With Lifelong Self-Doubt and Self-Criticism

Brief Report

Depressive Symptomatology Is Associated With Smaller Reductions in Drug Cue Reactivity During Extended-Release Naltrexone Treatment of Opioid Use Disorder

Commentary

Repetitive Transcranial Magnetic Stimulation for Treatment-Resistant Depression: Mismatch of Evidence and Insurance Coverage Policies in the United States

Clinical and Practical Psychopharmacology

How to Understand the 95% Confidence Interval Around the Relative Risk, Odds Ratio, and Hazard Ratio: As Simple as It Gets

Understanding Misunderstandings About the Relative Risk and Odds Ratio

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Volume 84 • 2023 • 3

Editorial

JCP’s New Look

In Memoriam

In Memoriam: Robert M. A. Hirschfeld, MD, 1943–2023

Narrative Review

Beyond “Psychotropic”: Repurposing Psychiatric Drugs for COVID-19, Alzheimer’s Disease, and Cancer

Meta-Analysis

The Neuropsychological Mechanisms of Treatment of Bipolar Disorder and Borderline Personality Disorder: Activation Likelihood Estimation Meta-Analysis of Brain Imaging Research

Systematic Review

Control Conditions in Randomized Trials of Psychedelics: An ACTTION Systematic Review

Original Research

The Protective Effect of Clozapine on Suicide: A Population Mortality Study of Statewide Autopsy Records in Maryland

Olanzapine/Samidorphan in Young Adults With Schizophrenia, Schizophreniform Disorder, or Bipolar I Disorder Who Are Early in Their Illness: Results of the Randomized, Controlled ENLIGHTEN-Early Study

The Efficacy of Lumateperone in Patients With Bipolar Depression With Mixed Features

Impact of the Abbreviated Suicide Crisis Syndrome Checklist on Clinical Decision Making in the Emergency Department

Treatment Journey From Diagnosis to the Successful Implementation of a Long-Acting Injectable Antipsychotic Agent in Young Adults With Schizophrenia

Generalizability of the Results of Efficacy Trials in First-Episode Schizophrenia: Comparing Outcome and Study Discontinuation of Groups of Participants in the Optimization of Treatment and Management of Schizophrenia in Europe (OPTiMiSE) Trial

Interpersonal Trauma and Depression Severity Among Individuals With Bipolar Disorder: Findings From the Prechter Longitudinal Study of Bipolar Disorder

Pandemics and Suicide Rates in Spain: From the Spanish Flu to COVID-19

50% Improvement: Should Treatment Response Go Beyond Symptom Improvement When Evaluating the Treatment of Depression?

Pregnancy-Specific Anxiety Tool (PSAT): Instrument Development and Psychometric Evaluation

Endothelial Function in Youth With Bipolar Disorder: Preliminary Evidence for Mood Polarity Differences

Lower Ghrelin Levels Are Associated With Higher Anxiety Symptoms in Adolescents and Young Adults With Avoidant/Restrictive Food Intake Disorder

Enhanced Primary Care for People With Serious Mental Illness: A Propensity Weighted Cohort Study

Impact of Tardive Dyskinesia on Physical, Psychological, Social, and Professional Domains of Patient Lives: A Survey of Patients in the United States

Cross Talk: Case Conferences From MGH

Pharmacotherapy and Ketamine Assisted Psychotherapy for Treatment-Resistant Depression: A Patient With Lifelong Self-Doubt and Self-Criticism

Brief Report

Depressive Symptomatology Is Associated With Smaller Reductions in Drug Cue Reactivity During Extended-Release Naltrexone Treatment of Opioid Use Disorder

Commentary

Repetitive Transcranial Magnetic Stimulation for Treatment-Resistant Depression: Mismatch of Evidence and Insurance Coverage Policies in the United States

Clinical and Practical Psychopharmacology

How to Understand the 95% Confidence Interval Around the Relative Risk, Odds Ratio, and Hazard Ratio: As Simple as It Gets

Understanding Misunderstandings About the Relative Risk and Odds Ratio

Celebrating85 Years

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Celebrating
85 Years

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more articles