The Journal of
Clinical Psychiatry

Depression (MDD)

Insights April 13, 2021

Distinguishing Bipolar Disorder From MDD: Points to Remember

Roger S. McIntyre, MD, FRCPC

J Clin Psychiatry 2019;80(3):ot18043ah2

Dr Roger S. McIntyre highlights 3 important considerations in the differential diagnosis of bipolar disorder and major depressive disorder: age at onset, episode recurrence, and delayed emergence of mania

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INFORMATION FROM INDUSTRY

AUVELITY is an FDA-approved treatment for adults with MDD. Auvelity, is a rapid-acting antidepressant with a multimodal mechanism, targeting both glutamatergic and monoaminergic pathways. Learn more about how AUVELITY is thought to work and side effects. Please see Important Safety Information within this document and the full Prescribing Information.

Vol 86 • 2025 • Number 1

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Patient Functioning and Life Engagement: Treatment Goals in MDD

September 7, 2022

Patients with MDD often report lack of motivation and energy and a feeling of disengagement from their own lives. Here, experts discuss treatment strategies that may be favorable for...

Christoph U. Correll , Zahinoor Ismail , Roger S. McIntyre , et al

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Measurement-Based Care for Depressive Disorders: Meta-Analysis of RCTs Shows Efficacy

May 17, 2022

Dr Lam explains in this video how for patients with depressive disorders treated with pharmacotherapy, measurement-based care is effective in decreasing symptom severity, promoting remission, and improving medication adherence.

Raymond W. Lam

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Progression of Symptoms Over the Course of Bipolar Disorder

April 13, 2021

Dr Joseph F. Goldberg discusses how symptoms and clinical presentation change over time in people with bipolar disorder, beginning from the prodromal phase

Joseph F. Goldberg

Distinguishing Bipolar Disorder From MDD: Points to Remember

Read the Current Issue

Psychological Support in Psychedelic Therapy

Long-Term Safety and Efficacy of Esmethadone in MDD

Suicidal Behaviors and Obstructive Sleep Apnea

A Collaborative Endeavor

Sex Differences in PTSD among US Military Veterans

Cannabis Use During Pregnancy and Neuropsychiatric Adverse Outcomes in Children and Young Adults

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Distinguishing Bipolar Disorder From MDD: Points to Remember

Read the Current Issue

Psychological Support in Psychedelic Therapy

Long-Term Safety and Efficacy of Esmethadone in MDD

Suicidal Behaviors and Obstructive Sleep Apnea

A Collaborative Endeavor

Sex Differences in PTSD among US Military Veterans

Cannabis Use During Pregnancy and Neuropsychiatric Adverse Outcomes in Children and Young Adults

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Patient Functioning and Life Engagement: Treatment Goals in MDD

Measurement-Based Care for Depressive Disorders: Meta-Analysis of RCTs Shows Efficacy

Progression of Symptoms Over the Course of Bipolar Disorder

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