The Journal of
Clinical Psychiatry

Schizophrenia/Schizoaffective Disorders

Letter to the Editor May 11, 2008

Intrinsic Activity of Aripiprazole Is Not 30% of Dopamine, But Only About 6% Under Ideal Antipsychotic Therapy

Takashi Hamamura, MD, PhD; Masafumi Kodama, MD, PhD; Toshiki Harada, MD

J Clin Psychiatry 2008;69(5):863-864

Article Abstract

Letter to the Editor

Sir: We read with great interest the recent review by Weidenet al. The authors state that the intrinsic activity of aripiprazoleis 30% of dopamine in their review. This idea may be originallyfrom the review by Grunder et al.

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Intrinsic Activity of Aripiprazole Is Not 30% of Dopamine, But Only About 6% Under Ideal Antipsychotic Therapy

Read the Current Issue

Changes in Cognition in Patients With Schizophrenia

Diagnostic Assessment via Telehealth vs Face-to-Face

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Medication Use and Lines of Treatment in Patients With Insomnia Disorder

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Intrinsic Activity of Aripiprazole Is Not 30% of Dopamine, But Only About 6% Under Ideal Antipsychotic Therapy

Read the Current Issue

Changes in Cognition in Patients With Schizophrenia

Diagnostic Assessment via Telehealth vs Face-to-Face

Prevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans

Bridge Symptoms Between Borderline Personality and PTSD

Gepirone-ER and Sexual Function in Patients with MDD

Medication Use and Lines of Treatment in Patients With Insomnia Disorder

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