Objective: This study examined the effects of electroconvulsive therapy (ECT) on suicidal ideation, suicide attempt, and emergency department use among homeless veterans receiving services in the Veterans Affairs (VA) health care system.
Methods: National VA administrative data from 2001 to 2017 were analyzed using propensity score matching to compare 1,524 homeless veterans who received ECT and 3,025 homeless veterans discharged from psychiatric inpatient units serving as matched controls.
Results: Homeless veterans who received ECT were significantly less likely to have used any ED services 30 and 90 days after their first ECT session compared to homeless veterans who did not receive ECT (OR = 0.65, 95% CI = 0.60–0.71; OR = 0.86, 95% CI = 0.81–0.93, respectively). Homeless veterans who received ECT showed reductions in suicidal ideation and suicide attempts after ECT, but these reductions were significantly less than homeless veterans who did not receive ECT 30 days, 90 days, and 1 year later (OR = 1.48–2.00).
Conclusions: ECT has the potential to reduce ED use among homeless veterans with ECT-responsive psychiatric conditions. Further study is needed on whether the treatment engagement required of ECT participants indirectly reduces use of acute services in this population.
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Tsai J, Doran KM, Rosenheck RA. When health insurance is not a factor: national comparison of homeless and nonhomeless US veterans who use Veterans Affairs Emergency Departments. Am J Public Health. 2013;103(suppl 2):S225–S231. PubMedCrossRef
Tsai J, Rosenheck RA. Risk factors for ED use among homeless veterans. Am J Emerg Med. 2013;31(5):855–858. PubMedCrossRef
Redelmeier DA, Molin JP, Tibshirani RJ. A randomised trial of compassionate care for the homeless in an emergency department. Lancet. 1995;345(8958):1131–1134. PubMedCrossRef
Han B, Wells BL. Inappropriate emergency department visits and use of the Health Care for the Homeless Program services by homeless adults in the northeastern United States. J Public Health Manag Pract. 2003;9(6):530–537. PubMedCrossRef
Tsai J, Szymkowiak D, Kertesz SG. Top 10 presenting diagnoses of homeless veterans seeking care at emergency departments. Am J Emerg Med. 2021;45:17–22, 22. PubMedCrossRef
Szymkowiak D, Montgomery AE, Johnson EE, et al. Persistent super-utilization of acute care services among subgroups of veterans experiencing homelessness. Med Care. 2017;55(10):893–900. PubMedCrossRef
Tsai J, Szymkowiak D, Radhakrishnan R. Antipsychotic medication prescriptions for homeless and unstably housed veterans in the Veterans Affairs health care system. J Clin Psychiatry. 2020;82(1):20m13372. PubMedCrossRef
Hermes E, Rosenheck R. Psychopharmacologic services for homeless veterans: comparing psychotropic prescription fills among homeless and non-homeless veterans with serious mental illness. Community Ment Health J. 2016;52(2):142–147. PubMedCrossRef
American Psychiatric Association. The Practice of Electroconvulsive Therapy Recommendations for Treatment, Training, and Privileging: Task Force Report of the American Psychiatric Association. 2nd edition. Washington, DC: American Psychiatric Association; 2001.
Weiner RD, Reti IM. Key updates in the clinical application of electroconvulsive therapy. Int Rev Psychiatry. 2017;29(2):54–62. PubMedCrossRef
Husain MM, Rush AJ, Fink M, et al. Speed of response and remission in major depressive disorder with acute electroconvulsive therapy (ECT): a Consortium for Research in ECT (CORE) report. J Clin Psychiatry. 2004;65(4):485–491. PubMedCrossRef
Medda P, Perugi G, Zanello S, et al. Response to ECT in bipolar I, bipolar II and unipolar depression. J Affect Disord. 2009;118(1–3):55–59. PubMedCrossRef
Petrides G, Fink M, Husain MM, et al. ECT remission rates in psychotic versus nonpsychotic depressed patients: a report from CORE. J ECT. 2001;17(4):244–253. PubMedCrossRef
Kho KH, van Vreeswijk MF, Simpson S, et al. A meta-analysis of electroconvulsive therapy efficacy in depression. J ECT. 2003;19(3):139–147. PubMedCrossRef
Case BG, Bertollo DN, Laska EM, et al. Declining use of electroconvulsive therapy in United States general hospitals. Biol Psychiatry. 2013;73(2):119–126. PubMedCrossRef
Sackeim HA. Modern electroconvulsive therapy: vastly improved yet greatly underused. JAMA Psychiatry. 2017;74(8):779–780. PubMedCrossRef
Wilkinson ST, Agbese E, Leslie DL, et al. Identifying recipients of electroconvulsive therapy: data from privately insured Americans. Psychiatr Serv. 2018;69(5):542–548. PubMedCrossRef
Gelenberg AJ, Freeman MP, Markowitz JC, et al; Work Group on Major Depressive Disorder. Practice Guideline for the Treatment of Patients With Major Depressive Disorder. 3rd ed. Arlington, VA: American Psychiatric Association; 2010.
Kellner CH, Fink M, Knapp R, et al. Relief of expressed suicidal intent by ECT: a consortium for research in ECT study. Am J Psychiatry. 2005;162(5):977–982. PubMedCrossRef
Ahmadi N, Moss L, Simon E, et al. Efficacy and long-term clinical outcome of comorbid posttraumatic stress disorder and major depressive disorder after electroconvulsive therapy. Depress Anxiety. 2016;33(7):640–647. PubMedCrossRef
Avery D, Winokur G. Suicide, attempted suicide, and relapse rates in depression. Arch Gen Psychiatry. 1978;35(6):749–753. PubMedCrossRef
Dennis NM, Dennis PA, Shafer A, et al. Electroconvulsive therapy and all-cause mortality in Texas, 1998–2013. J ECT. 2017;33(1):22–25. PubMedCrossRef
Liang CS, Chung CH, Ho PS, et al. Superior anti-suicidal effects of electroconvulsive therapy in unipolar disorder and bipolar depression. Bipolar Disord. 2018;20(6):539–546. PubMedCrossRef
Peltzman T, Shiner B, Watts BV. Effects of electroconvulsive therapy on short-term suicide mortality in a risk-matched patient population. J ECT. 2020;36(3):187–192. PubMedCrossRef
Watts BV, Peltzman T, Shiner B. Mortality electroconvulsive therapy [published online ahead of print June 24, 2021]. Br J Psychiatry. 2021. CrossRef
Shiner B, Peltzman T, Cornelius SL, et al. Recent trends in the rural-urban suicide disparity among veterans using VA health care. J Behav Med. 2021;44(4):492–506. PubMedCrossRef
Elixhauser A, Steiner C, Harris DR, et al. Comorbidity measures for use with administrative data. Med Care. 1998;36(1):8–27. PubMedCrossRef
Hoffmire C, Stephens B, Morley S, et al. VA Suicide Prevention Applications Network: a national health care system-based suicide event tracking system. Public Health Rep. 2016;131(6):816–821. PubMedCrossRef
Sackeim HA, Aaronson ST, Bunker MT, et al. The assessment of resistance to antidepressant treatment: rationale for the Antidepressant Treatment History Form: Short Form (ATHF-SF). J Psychiatr Res. 2019;113:125–136. PubMedCrossRef
Hunter CE, Palepu A, Farrell S, et al. Barriers to prescription medication adherence among homeless and vulnerably housed adults in three Canadian cities. J Prim Care Community Health. 2015;6(3):154–161. PubMedCrossRef
Coe AB, Moczygemba LR, Gatewood SBS, et al. Medication adherence challenges among patients experiencing homelessness in a behavioral health clinic. Res Social Adm Pharm. 2015;11(3):e110–e120. PubMedCrossRef
Peltzman T, Gottlieb DJ, Shiner B, et al. Electroconvulsive therapy in Veterans Health Administration hospitals: prevalence, patterns of use, and patient characteristics. J ECT. 2020;36(2):130–136. PubMedCrossRef
Tsai J, Cao X. Association between suicide attempts and homelessness in a population-based sample of US veterans and non-veterans. J Epidemiol Community Health. 2019;73(4):346–352. PubMedCrossRef
Hoffberg AS, Spitzer E, Mackelprang JL, et al. Suicidal self‐directed violence among homeless US veterans: a systematic review. Suicide Life Threat Behav. 2018;48(4):481–498. PubMedCrossRef
Tsai J, Trevisan L, Huang M, et al. Addressing veteran homelessness to prevent veteran suicides. Psychiatr Serv. 2018;69(8):935–937. PubMedCrossRef