The Journal of Clinical Psychiatry The Journal of Clinical Psychiatry

The Journal of
Clinical Psychiatry

Empowering mental health professionals with peer-reviewed psychiatric research and insights

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Page 15

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JCP
THC for Neuropsychiatric Symptoms of Dementia
Original Research

September 18, 2023

Neuropsychiatric symptoms (NPS) in dementia are challenging to manage, and available treatments have a significant side effect profile. This study evaluated the effectiveness of dispensary-obtained tetrahydrocannabinol for patients with…
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JCP
Excess Mortality Associated With Schizophrenia
Original Research

September 13, 2023

Females, patients with connective tissue disorders, and those aged 20 years or younger were especially impacted by the effect of schizophrenia on increasing mortality.
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JCP
Coprescribing of Z-Drugs and Opioids During COVID-19
Original Research

September 11, 2023

Coprescribing of nonbenzodiazepine sedative-hypnotics, or “Z-drugs,” with opioids was more common among older patients, although the odds of coprescription among patients overall decreased over the COVID-19 lockdown period.
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JCP
Mortality Within 1 Year After Suicide Attempt
Original Research

September 11, 2023

One in 100 people who attempted suicide died by suicide within 1 year; men aged 45 years or older were at greater risk than other demographic groups.
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JCP
Risk-Sensitive Decision-Making and Self-Harm
Original Research

September 6, 2023

Greater risk-taking has been associated with suicide attempts in youth with major depression. This study examined whether the association between self-harm and risk-sensitive decision-making is true for bipolar disorder…
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JCP
Safety and Efficacy of Aripiprazole 2-Month Ready-to-Use 960 mg
Original Research

September 4, 2023

A new formulation of injectable aripiprazole for administration every 2 months showed similar rates of treatment-emergent adverse events to aripiprazole once-monthly 400 mg. Patients in both groups remained clinically…
, , , et al
JCP
Brexpiprazole in Patients With MDD and Prediabetes
Original Research

August 28, 2023

Some atypical antipsychotics, while efficacious as adjunctive treatments in major depressive disorder (MDD), can lead to adverse effects and weight gain. Adjunctive brexpiprazole had a limited impact on metabolic…
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JCP
Alcohol Use Disorder Treatment in Sexually and Gender Diverse Patients
Original Research

August 28, 2023

Sexually and gender diverse (SGD) patients had significantly higher rates of both AUD diagnosis and care utilization compared with non-SGD patients.
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JCP
Clozapine Delay and Schizophrenia Outcomes
Original Research

August 23, 2023

Clozapine is the drug of choice for treatment-resistant schizophrenia, but delays in initiation and underutilization may hinder its effectiveness. This study examined whether delay in clozapine initiation led to…
, , , et al
JCP
COVID-19 Delirium and Motoric Subtypes: Improving Outcomes
Commentary

August 21, 2023

Randall T. Espinoza, MD, and Aaron Kaufman, MD, discuss a study by Trevisan et al and reflect on lessons learned during the pandemic about detecting and managing delirium.
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JCP
Delirium and Mortality in COVID-19 Patients
Original Research

August 21, 2023

COVID-19 patients with early onset delirium had a 2-fold increased mortality risk—both in-hospital and after discharge—than those without delirium.
, , , et al
JCP
Nitrous Oxide Reduced Suicidal Ideation in Treatment-Resistant Major Depression
Brief Report

August 16, 2023

In this exploratory analysis, 54% of TRD patients receiving nitrous oxide had a reduction in suicidal ideation, compared with 12% in the placebo group.
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