The Journal of Clinical Psychiatry The Journal of Clinical Psychiatry

The Journal of
Clinical Psychiatry

Empowering mental health professionals with peer-reviewed psychiatric research and insights

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JCP
Antipsychotic Efficacy of KarXT (Xanomeline−Trospium)
Original Research

image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ May 11, 2022

This post hoc analysis of phase 2 data evaluated rates and time course of response with the new combination oral agent KarXT (xanomeline−trospium) in the treatment of schizophrenia.
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JCP
Daily Dose Effects of Risperidone on Metabolic Parameters
Original Research

May 9, 2022

This study investigated whether dose is a factor in the development of metabolic side effects with atypical antipsychotics.
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JCP
Corrigendum to “Decreases in Suicidality Following Psychedelic Therapy: A Meta-Analysis of Individual Patient Data Across Clinical Trials”
Letter to the Editor

May 9, 2022

The authors note two suicidality-related events that occurred within the studies included in their recent meta-analysis.
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JCP
A Practical Guide for Tailoring Treatment Choices in Interventional Psychiatry
ASCP Corner

May 4, 2022

When 2 or more antidepressant trials have failed in patients with MDD, what comes next? This article compares 3 next-step interventions—TMS, esketamine/ketamine, and ECT—with a focus on incorporating the…
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JCP
Epilepsy and Suicide Attempt
Original Research

May 2, 2022

From a sample of 1,229 adults who attempted suicide, this study found an elevated frequency of epilepsy and identified clinical factors that might play a role.
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JCP
Receipt of Antidepressants and Retention in Buprenorphine Treatment for OUD
Original Research

April 27, 2022

This study investigated whether receiving antidepressants increases the chance that patients with opioid use disorder will remain on buprenorphine treatment.
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JCP
Peer-Delivered Psychotherapy for Postpartum Depression: Reply to Tomfohr-Madsen et al
Letter to the Editor

April 27, 2022

Dr O’Hara responds to a letter regarding his recent commentary on peer-delivered psychotherapy.
JCP
Peer-Led Psychotherapy: The Time Is Now
Letter to the Editor

April 27, 2022

Tomfohr-Madsen et al respond to O’Hara’s recent commentary on peer-delivered psychotherapy for postpartum depression.
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JCP
Economic Burden of PTSD in the US
Original Research

April 25, 2022

Studies on the economic burden of posttraumatic stress disorder (PTSD) mostly focus on military populations and/or direct health care costs. This study estimated the economic burden of PTSD in…
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JCP
Transdiagnostic PRS Prediction of Mood Disorders
Original Research

April 20, 2022

Mood disorders often co-occur with behavior disorders in children and adolescents. This study explored if polygenic risk scores based on external genome-wide association studies of these disorders could improve…
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JCP
Co-Occurring Depression and Response During OUD Treatment
Original Research

April 18, 2022

This study looked at the relationship between opioid use disorder treatment and depression, and whether remission of depression is associated with lower relapse risk.
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JCP
Twelve-Month Outcomes for Remitters Following ECT for Depression
Letter to the Editor

April 18, 2022

Jelovac and McLoughlin respond to Dr Andrade’s recent Clinical and Practical Psychopharmacology article commenting on their study of maintenance ECT.
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