Reply to Letter to the Editor "Oxybutynin and Intranasal Desmopressin for Clozapine-Induced Urinary Incontinence"

Letter to the Editor

Sir: We are pleased that others have confirmed our observation of urinary incontinence associated with clozapine. We agree that, absent systematic ascertainment, the actual incidence of this troublesome side effect is likely to be underestimated. Lurie and Hosmer report that they have had success in treating this side effect with oxybutynin. In our hands, this proved to be ineffective.