Objective: Insomnia is prevalent and is associated with a range of negative sequelae. Cognitive behavioral treatment for insomnia (CBT-I) is the recommended intervention, but availability is limited. Telehealth provides increased access, but its efficacy is not certain. The objective of this study was to compare the efficacy of CBT-I delivered by telehealth to in-person treatment and to a waitlist control.
Methods: Individuals with DSM-5 insomnia disorder (n = 60) were randomized to telehealth CBT-I, in-person CBT-I, or 8-week waitlist control. CBT-I was delivered over 6–8 weekly sessions by video telehealth or in-person in an outpatient clinic. Follow-up assessments were at 2 weeks and 3 months posttreatment. The Insomnia Severity Index (ISI) was the primary outcome. Change in ISI score was compared between the CBT-I group in an intent-to-treat, noninferiority analysis using an a priori margin of −3.0 points. All analyses were conducted using mixed-effects models. Data collection occurred from November 2017–July 2020.
Results: The mean (SD) change in ISI score from baseline to 3-month follow-up was −7.8 (6.1) points for in-person CBT-I, −7.5 (6.9) points for telehealth, and −1.6 (2.1) for waitlist, and the difference between the CBT-I groups was not statistically significant (t28 = −0.98, P = .33). The lower confidence limit of this between-group difference in the mean ISI changes was greater than the a priori margin of −3.0 points, indicating that telehealth treatment was not inferior to in-person treatment. There were significant improvements on most secondary outcome measures but no group differences.
Conclusions: Telehealth CBT-I may produce clinically significant improvements in insomnia severity that are noninferior to in-person treatment. CBT-I is also associated with significant gains across a range of domains of functioning. Telehealth is a promising option for increasing access to treatment without loss of clinical gains.
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Roth T, Coulouvrat C, Hajak G, et al. Prevalence and perceived health associated with insomnia based on DSM-IV-TR; International Statistical Classification of Diseases and Related Health Problems, Tenth Revision; and Research Diagnostic Criteria/International Classification of Sleep Disorders, Second Edition criteria: results from the America Insomnia Survey. Biol Psychiatry. 2011;69(6):592–600. PubMedCrossRef
Shochat T, Umphress J, Israel AG, et al. Insomnia in primary care patients. Sleep. 1999;22(suppl 2):S359–S365. PubMed
Benca RM. Consequences of insomnia and its therapies. J Clin Psychiatry. 2001;62(suppl 10):33–38. PubMed
Fullerton DS. The economic impact of insomnia in managed care: a clearer picture emerges. Am J Manag Care. 2006;12(8 suppl):S246–S252. PubMed
Mitchell MD, Gehrman P, Perlis M, et al. Comparative effectiveness of cognitive behavioral therapy for insomnia: a systematic review. BMC Fam Pract. 2012;13(1):40. PubMedCrossRef
Smith MT, Perlis ML, Park A, et al. Comparative meta-analysis of pharmacotherapy and behavior therapy for persistent insomnia. Am J Psychiatry. 2002;159(1):5–11. PubMedCrossRef
Morland LA, Greene CJ, Rosen C, et al. Issues in the design of a randomized noninferiority clinical trial of telemental health psychotherapy for rural combat veterans with PTSD. Contemp Clin Trials. 2009;30(6):513–522. PubMedCrossRef
Morland LA, Greene CJ, Rosen CS, et al. Telemedicine for anger management therapy in a rural population of combat veterans with posttraumatic stress disorder: a randomized noninferiority trial. J Clin Psychiatry. 2010;71(7):855–863. PubMedCrossRef
Morland LA, Mackintosh MA, Rosen CS, et al. Telemedicine versus in-person delivery of cognitive processing therapy for women with posttraumatic stress disorder: a randomized noninferiority trial. Depress Anxiety. 2015;32(11):811–820. PubMedCrossRef
Holmqvist M, Vincent N, Walsh K. Web- vs telehealth-based delivery of cognitive behavioral therapy for insomnia: a randomized controlled trial. Sleep Med. 2014;15(2):187–195. PubMedCrossRef
Arnedt JT, Conroy DA, Mooney A, et al. Telemedicine versus face-to-face delivery of cognitive behavioral therapy for insomnia: a randomized controlled noninferiority trial. Sleep (Basel). 2021;44(1):zsaa136. PubMedCrossRef
Bastien CH, Vallières A, Morin CM. Validation of the Insomnia Severity Index as an outcome measure for insomnia research. Sleep Med. 2001;2(4):297–307. PubMedCrossRef
Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606–613. PubMedCrossRef
Spitzer RL, Kroenke K, Williams JB, et al. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166(10):1092–1097. PubMedCrossRef
Mundt JC, Marks IM, Shear MK, et al. The Work and Social Adjustment Scale: a simple measure of impairment in functioning. Br J Psychiatry. 2002;180(5):461–464. PubMedCrossRef
Smets EM, Garssen B, Bonke B, et al. The Multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue. J Psychosom Res. 1995;39(3):315–325. PubMedCrossRef
Ware J Jr, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996;34(3):220–233. PubMedCrossRef
Benz F, Knoop T, Ballesio A, et al. The efficacy of cognitive and behavior therapies for insomnia on daytime symptoms: a systematic review and network meta-analysis. Clin Psychol Rev. 2020;80:101873. PubMedCrossRef
Agarwal N, Jain P, Pathak R, et al. Telemedicine in India: a tool for transforming health care in the era of COVID-19 pandemic. J Educ Health Promot. 2020;9(1):190. PubMedCrossRef
Ramaswamy A, Yu M, Drangsholt S, et al. Patient satisfaction with telemedicine during the COVID-19 pandemic: retrospective cohort study. J Med Internet Res. 2020;22(9):e20786. PubMedCrossRef
Torales J, O’Higgins M, Castaldelli-Maia JM, et al. The outbreak of COVID-19 coronavirus and its impact on global mental health. Int J Soc Psychiatry. 2020;66(4):317–320. PubMedCrossRef
Altena E, Baglioni C, Espie CA, et al. Dealing with sleep problems during home confinement due to the COVID-19 outbreak: practical recommendations from a task force of the European CBT-I Academy. J Sleep Res. 2020;29(4):e13052. PubMedCrossRef
Ho FY, Chan CS, Lo WY, et al. The effect of self-help cognitive behavioral therapy for insomnia on depressive symptoms: an updated meta-analysis of randomized controlled trials. J Affect Disord. 2020;265:287–304. PubMedCrossRef
Grandner MA. Sleep, health, and society. Sleep Med Clin. 2020;15(2):319–340. PubMedCrossRef
Thomas A, Grandner M, Nowakowski S, et al. Where are the behavioral sleep medicine providers and where are they needed? a geographic assessment. Behav Sleep Med. 2016;14(6):687–698. PubMedCrossRef