Major Depressive Disorder (MDD) is a debilitating condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest in daily activities. Understanding its underlying causes and effective treatments is crucial for patient well-being. The Journal of Clinical Psychiatry provides a comprehensive look into MDD, offering evidence-based therapeutic approaches and the latest research findings. Our expert editors ensure content is relevant and actionable, aiding psychiatrists in offering holistic care to those grappling with depression.
Depression and Major Depressive Disorder
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Recently published articles about Depression (MDD)
Original Research
Psychotic Features in Patients With MDD
January 15, 2019
Psychotic features within major depressive disorder (MDD) are associated with poor treatment outcome. This article explores whether sociodemographic and clinical characteristics of and pharmacologic treatments received by patients with...
Original Research
Cost-Effectiveness of "Next-Step" Depression Treatment Strategies
December 18, 2018
Aripiprazole is commonly prescribed as a next-step pharmacotherapy for treatment-resistant depression, but its cost-effectiveness as an adjunct to antidepressants is unknown. Read this article to learn how the cost-effectiveness...
Original Research
Sudden Improvement in Symptoms During Antidepressant Clinical Trials
December 4, 2018
If a patient's depressive symptoms subside very quickly after antidepressant treatment is initiated, do those gains represent a true and lasting response? This study examined whether sudden improvement in...
Original Research
Depression, Cognition, and Functional Impairment
November 13, 2018
Depression is strongly associated with functional impairment. Some hypothesize that cognitive dysfunction, which is also often associated with depression, might mediate the impact of depression on functioning. This study...
