The Journal of
Clinical Psychiatry

Empowering mental health professionals with peer-reviewed psychiatric research and insights

Back to top Open menu arrow
Current Issue Digital Edition Archives Authors Reviewers

Just Published

JCP
Psilocybin-Assisted Therapy for Bipolar II Depression
Original Research

Psilocybin-Assisted Therapy for Bipolar II Depression

September 21, 2026

Following the 10 mg session, MADRS scores improved significantly, with 4 participants (28.5%) meeting remission criteria and therefore not proceeding to the 25 mg session.
, , , et al
JCP
The Role of Chronic Anhedonia in the Relationship Between Treatment-Resistant Depression and Suicidality
Original Research

The Role of Chronic Anhedonia in the Relationship Between Treatment-Resistant Depression and Suicidality

September 21, 2026

Chronic anhedonia is significantly associated with an increased risk of suicidal ideation and attempts in patients with treatment-resistant depression.
, , , et al
JCP
Correction

Correction. Evaluation of Sexual Function With Adjunctive Lumateperone in Patients With Major Depressive Disorder

September 17, 2026

Insightful. Evidence-based. Human-centered.

The Journal of Clinical Psychiatry Podcast

Explore the science, practice, and human side of mental health care. Hosted by Dr. Ben Everett,  the series brings together leading voices in psychiatry, neuroscience, and behavioral medicine to discuss the evidence shaping clinical care today.

Each episode features thoughtful conversations with JCP authors, academic experts, and frontline clinicians exploring disorders across the mental health continuum, from schizophrenia and mood disorders to anxiety, depression, and sleep-related conditions. By bridging research and real-world practice, the podcast delivers insights that empower psychiatrists, nurse practitioners, physician associates, and primary care clinicians to deliver better care for patients with mental illness.

Learn More

 

Explore Special Sections

Focus on Childhood and Adolescent Mental Health Early Career Psychiatrists Focus on Geriatric Psychiatry Focus on Psychotherapy Focus on Psychosis Focus on Suicide Focus on Women’s Mental Health
The Journal of Clinical Psychiatry September 2026 cover featuring key articles on depression therapy

Vol 87 • 2026 • Number 3

Read the Current Issue

Original Research

Inhaled Mebufotenin (GH001) for Adult Patients with Postpartum Depression

Original Research

US Mortality Involving Obesity and Psychiatric Disorders

Academic Highlights

Treatment-Resistant Depression as a Dynamic Continuum: A Consensus Panel Report

Original Research

Effects of Brexpiprazole on Functioning in Patients with Schizophrenia Who Have Hostility and Agitation Symptoms

Original Research

Exposure-Based Video Therapy for OCD and PTSD

Original Research

Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder and Anxious Distress
View current Issue

Original Research

JCP
Long-Acting Injectable Antipsychotics and Clozapine in Coordinated Specialty Care: Data From EPINET
Original Research

Long-Acting Injectable Antipsychotics and Clozapine in Coordinated Specialty Care: Data From EPINET

September 14, 2026

Data from the EPINET project reveal wide variation in the prescription of LAIs and clozapine across first-episode specialty care clinics.
, , , et al
JCP
Utilizing a Smartphone Application for Perinatal Depression Screening and Care Linkages
Original Research

Utilizing a Smartphone Application for Perinatal Depression Screening and Care Linkages

September 9, 2026

The prevalence of probable perinatal depression was comparable to that in US women, demonstrating the app’s ability to identify perinatal depression.
, , , et al
JCP
Using Speech to Predict MDD and GAD During Pregnancy
Original Research

Using Speech to Predict MDD and GAD During Pregnancy

September 9, 2026

Influential speech features for prediction of MDD and GAD during pregnancy were similar to those in the general population.
, , , et al

Review Articles

JCP
Pharmacotherapies for Co-Occurring Stimulant Use Disorder and ADHD
Meta-Analysis

Pharmacotherapies for Co-Occurring Stimulant Use Disorder and ADHD

August 31, 2026

Stimulant-based pharmacotherapies, particularly higher-dose methylphenidate and mixed amphetamine salts, were associated with superior outcomes for both stimulant-use indicators and ADHD symptoms.
, , , et al
JCP
Placebo Effects in Alcohol, Cocaine, and Methamphetamine Use Disorder
Meta-Analysis

Placebo Effects in Alcohol, Cocaine, and Methamphetamine Use Disorder

June 10, 2026

Placebo treatment led to reductions in craving scores across all three disorders, although statistical significance was achieved only in alcohol use disorder.
, , , et al
JCP
Systematic Review and Meta-Analysis of Use of Mood Stabilizers in Adolescents With Nonsuicidal Self-Injury
Meta-Analysis

Systematic Review and Meta-Analysis of Use of Mood Stabilizers in Adolescents With Nonsuicidal Self-Injury

May 18, 2026

Severity of anxiety, depression, impulsivity, and self-injury was significantly reduced following treatment with mood stabilizers.
, , , et al
JCP
Effectiveness of Peer-Administered Interventions for Perinatal Depression or Anxiety
Meta-Analysis

Effectiveness of Peer-Administered Interventions for Perinatal Depression or Anxiety

December 8, 2025

Peer-administered interventions are effective at improving perinatal depression, with peer-delivered psychotherapies being the most effective.
, , , et al
JCP
Burnout in Psychiatric Doctors Before and After the COVID-19 Pandemic
Meta-Analysis

Burnout in Psychiatric Doctors Before and After the COVID-19 Pandemic

September 29, 2025

The prevalence of burnout was 37.5% prior to the COVID-19 pandemic and 32.0% following the pandemic.
, ,
JCP
Treating PTSD in Military Populations
Meta-Analysis

Treating PTSD in Military Populations

March 24, 2025

Integrating psychotherapies and pharmacotherapies may address multiple dimensions of PTSD more effectively than monotherapies.
, , , et al

Read articles from ASCP Corner

ASCP Corner

Letters to the Editor

JCP
Genetically Informed Triangulation Can Strengthen Counseling About Gestational Antidepressant Exposure
Letter to the Editor

Genetically Informed Triangulation Can Strengthen Counseling About Gestational Antidepressant Exposure

August 19, 2026

The authors discuss a recent article by Chittaranjan Andrade.
, ,
JCP
Psychotherapy and the Operational Definition of Treatment-Resistant Depression
Letter to the Editor

Psychotherapy and the Operational Definition of Treatment-Resistant Depression

August 19, 2026

Discusses recent consensus-based recommendations from Marques et al on treatment selection for treatment-resistant depression.
, ,
JCP
Psychotherapy, Pharmacotherapy, and Neuromodulatory Interventions in Operational Definitions of TRD: Reply to De Oliveira Reis et al
Letter to the Editor

Psychotherapy, Pharmacotherapy, and Neuromodulatory Interventions in Operational Definitions of TRD: Reply to De Oliveira Reis et al

August 19, 2026

Marques et al reply to commentary on their consensus-based recommendations for treatment-resistant depression.
, ,
JCP
GLP-1 Receptor Agonists for Non-obese Asian Patients With Schizophrenia
Letter to the Editor

GLP-1 Receptor Agonists for Non-obese Asian Patients With Schizophrenia

July 6, 2026

The author recommends considering ethnic variations in metabolic pathophysiology to optimize use of GLP-1 RAs for mental disorders.
JCP
Metformin for Prevention of Antipsychotic-Induced Weight Gain: The Optimal Strategy
Letter to the Editor

Metformin for Prevention of Antipsychotic-Induced Weight Gain: The Optimal Strategy

April 6, 2026

Dr Huang discusses the potential for B12 deficiency in patients coprescribed antipsychotics and metformin.
JCP
Vitamin B12 Deficiency Risk With Metformin for Weight Management in Second-Generation Antipsychotic Recipients: Reply to Mulsant et al
Letter to the Editor

Vitamin B12 Deficiency Risk With Metformin for Weight Management in Second-Generation Antipsychotic Recipients: Reply to Mulsant et al

March 18, 2026

Daggolu and Chen reply to a letter commenting on their study of metformin use in patients receiving second-generation antipsychotics.
,

Commentaries

JCP
Voice of the Patient
Commentary

Voice of the Patient

September 9, 2026

Discusses a recent study by Bayrampour et al of the use of speech features for prediction of MDD and GAD during pregnancy.
JCP
ADHD Medication Safety in Pregnancy: Precise Estimates, Uncertain Causal Inference
Commentary

ADHD Medication Safety in Pregnancy: Precise Estimates, Uncertain Causal Inference

August 26, 2026

Comments on a recent study by Babinski and Tuan finding ADHD medication use predictive of adverse pregnancy outcomes.
JCP
Psychiatrists and Medical Aid in Dying: Entering Uncharted Waters
Commentary

Psychiatrists and Medical Aid in Dying: Entering Uncharted Waters

July 1, 2026

This commentary argues that psychiatric participation in MAID differs meaningfully from traditional capacity evaluations and conventional suicide prevention and therefore demands its own practice standards.
JCP
The Challenges of PTSD Prevention: Placing Benzodiazepine Use in Context
Commentary

The Challenges of PTSD Prevention: Placing Benzodiazepine Use in Context

June 22, 2026

The authors discuss the findings of a recent study by Rahamim et al.
,
JCP
Prescribing GLP-1 Receptor Agonists for Persons With Mental Disorders: Evidence-Based and Aspirational Targets
Commentary

Prescribing GLP-1 Receptor Agonists for Persons With Mental Disorders: Evidence-Based and Aspirational Targets

June 1, 2026

Evidence-based prescription of GLP-1 RAs in persons with serious mental illness and/or substance use disorders holds promise to improve their health and wellbeing and possibly reduce excess mortality.
JCP
The Patient Perspective on Tardive Dyskinesia
Commentary

The Patient Perspective on Tardive Dyskinesia

April 29, 2026

Patients’ perspectives on their experiences with tardive dyskinesia provide critical insights that go beyond the information provided by clinical assessments.

More JCP Articles

JCP
Paliperidone Palmitate 351 mg as Alternative Maintenance Doses in Patients With Schizophrenia or Schizoaffective Disorder
Insights ▶ Video

Paliperidone Palmitate 351 mg as Alternative Maintenance Doses in Patients With Schizophrenia or Schizoaffective Disorder

September 16, 2026

This analysis suggests that maintenance doses of paliperidone palmitate 351 mg at different dosing intervals may offer additional treatment options for clinical use.
, , , et al
JCP
The Regulatory Maze of Ketamine and Psychedelics with Benjamin Brody, MD
Podcast

The Regulatory Maze of Ketamine and Psychedelics with Benjamin Brody, MD

September 8, 2026

Benjamin Brody, MD, discusses ketamine’s REMS-regulated future, esketamine safety, dysphoric dissociation, and what psilocybin approval means for psychiatry.
,
JCP
Evaluation of Sexual Function With Adjunctive Lumateperone in Major Depressive Disorder
Original Research

Evaluation of Sexual Function With Adjunctive Lumateperone in Major Depressive Disorder

September 2, 2026

Adjunctive lumateperone 42 mg did not worsen sexual functioning and was not associated with treatment-related sexual dysfunction.
, , , et al
JCP
Electroconvulsive Therapy and All-Cause, Nonsuicide, and Suicide Mortality
Clinical and Practical Psychopharmacology

Electroconvulsive Therapy and All-Cause, Nonsuicide, and Suicide Mortality

August 31, 2026

Evidence on the association of ECT with lower risk of short- and long-term all-cause mortality, nonsuicide mortality, and suicide mortality is reviewed.
JCP
Obstetric Risk Associated with Stimulant vs Nonstimulant Treatment
Original Research

Obstetric Risk Associated with Stimulant vs Nonstimulant Treatment

August 26, 2026

Stimulant and nonstimulant use during pregnancy were both associated with increased risk for obstetric complications vs no medication.
,
JCP
The Prescriber’s Guide to Oral Ketamine for Depression
Clinical and Practical Psychopharmacology

The Prescriber’s Guide to Oral Ketamine for Depression

August 26, 2026

Explains clinical contexts in which oral ketamine can be used and presents a detailed protocol for the use of this intervention.
JCP
From Screening to Treatment: Rethinking Suicide Risk with Elizabeth Ballard, PhD
Podcast

From Screening to Treatment: Rethinking Suicide Risk with Elizabeth Ballard, PhD

August 25, 2026

Dr. Elizabeth Ballard discusses suicide risk screening tools, ketamine’s rapid antisuicidal effects, sleep biomarkers, and ethics of suicide research.
,
JCP
Life’s Essential 8 Cardiovascular Health and Suicide Mortality
Original Research

Life’s Essential 8 Cardiovascular Health and Suicide Mortality

August 19, 2026

Poor cardiovascular health status, as reflected by a low Life’s Essential 8 score, was associated with suicide mortality.
,
JCP
Persistent Gaps in Diversity of US Antidepressant Trials
Original Research

Persistent Gaps in Diversity of US Antidepressant Trials

August 12, 2026

Reporting gaps and multiple underrepresented groups persist in US antidepressant trials, limiting generalizability.
, , , et al
JCP
Time Trends in Maternal ADHD and Medication Use in Pregnancy
Original Research

Time Trends in Maternal ADHD and Medication Use in Pregnancy

August 12, 2026

The 4-fold increase in maternal ADHD in pregnancy over a 20-year period and 2-fold increase in use of stimulants before and during pregnancy underline the need for guidance on…
, , , et al
JCP
Feeding the Mind: Metabolism in Psychiatry with David T. Liebers, MD, MPhil, MPP
Podcast

Feeding the Mind: Metabolism in Psychiatry with David T. Liebers, MD, MPhil, MPP

August 11, 2026

Dr. David Liebers on metabolic psychiatry: ketogenic diets, SGLT2 inhibitors, and metformin for bipolar disorder, schizophrenia, and mitochondrial dysfunction.
,
JCP
Relative Infant Dose for Maternal Use of Drugs During Breastfeeding
Clinical and Practical Psychopharmacology

Relative Infant Dose for Maternal Use of Drugs During Breastfeeding

August 10, 2026

Relative infant dose is explained using a worked example, and clinically important issues in its derivation, interpretation, and application are discussed.

Insightful. Evidence-based. Human-centered.

Listen Now
The Journal of Clinical Psychiatry podcast cover with Benjamin Brody, MD

Subscribe to read
more articles

Subscribe