Primary Care Companion for CNS Disorders Primary Care Companion for CNS Disorders

The Primary
Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

Back to top Open menu arrow
Current Issue Archives Authors Reviewers

Just Published

PCC
What Internists and Neurologists Know and Think About Catatonia
Original Research

April 17, 2025

The authors designed and conducted a survey-based study to raise catatonia awareness among internists and neurologists and to inform future educational campaigns.
, , , et al
PCC
Psychological Morbidities in Hospital Staff During Nipah Virus
Original Research

April 15, 2025

The authors evaluated the prevalence of depression and anxiety among health care workers in a tertiary care hospital during a period of heightened concern due to Nipah virus exposure.
, , , et al
PCC
Oxcarbazepine/Aripiprazole Interaction and Bipolar Relapse
Case Report

April 10, 2025

This case highlights the interaction between aripiprazole and oxcarbazepine, resulting in subtherapeutic levels of aripiprazole and recurrence of manic symptoms in a patient with bipolar I disorder.
,
PCC
Quality Indicators in Community Mental Health Services: A Scoping Review
Review Article

April 8, 2025

Engaging communities in mental health initiatives can improve understanding and support for individuals with mental health disorders and improve quality of the service.
, ,
PCC
Is My Patient Diverting Their Lorazepam?
Case Report

April 3, 2025

Urine drug testing is used to monitor compliance in patients prescribed controlled substances; a negative test can suggest diversion to family or friends or illicit sale of the medication.
, , , et al
PCC
Managing Anxiety, Agitation, and Pain in Critically Ill Patients
Rounds in the General Hospital

April 1, 2025

Pain, fear, anxiety, sleep disturbances, and agitation are common symptoms among critically ill patients, causing distress, interfering with medical care, and contributing to morbidity post discharge.
, , , et al

Vol 27 • 2025 • Number 1

Read the Current Issue

Case Report

Thyrotoxic Psychosis in Graves’ Disease

Rounds in the General Hospital

Psychosis-Related PTSD

Case Report

Factitious Disorder in the Context of Abuse in an Adolescent

Rounds in the General Hospital

Wishing That Your Patient Would Die: Reasons and Reactions

Case Report

Frontal Lobe Syndrome Unveils an Unexpected Diagnosis

Case Report

Low-Dose Clozapine in Schizophrenia With Aggression
View current Issue

Explore Special Sections

View all topics
Rounds in the General Hospital Rounds from Banner Alzheimer's Institute

Original Research

PCC
Association of Pregnancy-Related Anxiety With Perceived Social Support: An Observational Study Among Third-Trimester Antenatal Women
Original Research

March 20, 2025

Late-pregnancy anxiety was linked to perceived social support, and specific pregnancy-related anxiety themes, such as concerns about giving birth, the child’s health, one’s own appearance, correlated with distinct perceived…
, , , et al
PCC
Sleepiness in Colombian Medical Students
Original Research

February 18, 2025

This study investigated the prevalence of sleepiness and associated variables among medical students at a university in Santa Marta, Colombia.
, ,
PCC
Medical Education and the COVID-19 Pandemic
Original Research

February 11, 2025

The pandemic disrupted traditional undergraduate medical education and required adaptations to the clerkship curriculum, such as integration of virtual patient care and telehealth services, to provide meaningful learning experiences.
, ,

Review Articles

PCC
Dextromethorphan-Quinidine for Agitation in Dementia
Narrative Review

November 14, 2024

The authors provide an updated summary of the literature on dextromethorphan-quinidine for the treatment of agitation in patients with dementia.
, ,
PCC
Improving Collaboration Between Neuropsychology and Primary Care
Narrative Review

October 31, 2024

Collaboration between neuropsychologists and physicians significantly improves patient care by enhancing diagnostic precision and treatment planning. Read on to find out more.
, ,
PCC
Understanding the Child and Adolescent Mental Health Crisis
Narrative Review

October 24, 2024

The authors delve into current mental health challenges facing children and youth, examining perspectives from both pre-pandemic and pandemic periods.
, , , et al
PCC
Management of Sleep Disturbances in Veterans Following Mild TBI
Narrative Review

September 12, 2024

The authors developed an evidence- and consensus-based clinical recommendation regarding primary care management of insufficient and disturbed sleep associated with concussion/mild traumatic brain injury in service members and veterans.
, , , et al
PCC
Management of ADHD in Adolescents and Young Adults
Narrative Review

August 6, 2024

Drawing on their clinical experiences of implementing evidence-based guidelines and feedback from patients, the authors describe innovative strategies and solutions for improving the management of ADHD in adolescents and…
, ,
PCC
Tech Gaming Designs, Neurodevelopmental Vulnerabilities, and Internet Gaming Disorder Risk
Narrative Review

July 23, 2024

The authors review the relevant research in the field of internet gaming disorder and provide an approach to identification and management.
, ,

Rounds in the General Hospital

PCC
Prolonged Grief: Etiology and Management
Rounds in the General Hospital

February 4, 2025

Prolonged grief disorder has several features that overlap with depression and PTSD but is a distinct entity for which a well-validated, targeted treatment is available.
, ,
PCC
Management of Insomnia in the General Hospital
Rounds in the General Hospital

January 21, 2025

Although the etiology of insomnia is often multi-factorial, both nonpharmacologic and various pharmacologic approaches can provide rapid relief; unfortunately, each is associated with drug-drug interactions and potentially problematic side…
, , , et al
PCC
Focal Impaired Awareness Seizures: Evaluation and Management
Rounds in the General Hospital

January 3, 2025

Focal impaired awareness seizures can look like other psychiatric, neurological, and medical presentations, and due to the changes in affect, behavior, and cognition, are often misdiagnosed as a primary…
, , , et al
PCC
Comorbid Bipolar Disorder and PTSD
Rounds in the General Hospital

December 24, 2024

Bipolar disorder and PTSD are highly comorbid conditions, and pharmacologic management poses unique challenges, as side effects of the commonly used medications for one disorder can worsen the symptoms…
, , , et al
PCC
Etiology, Prevention, and Management of TD
Rounds in the General Hospital

November 19, 2024

It is critical to detect TD early in its course and adjust medications to those that are less likely to cause it. Left untreated, TD is typically irreversible, disfiguring,…
, , , et al
PCC
Treatment of Pain in the Context of Alcohol and Substance Use Disorders
Rounds in the General Hospital

October 17, 2024

When prescribing opioids for pain, prescription monitoring programs should be checked, regular urine toxicology screening should be conducted, and patients with an opioid use disorder should receive FDA-approved medication…
, , , et al

Case Reports

PCC
First-Episode Psychosis and Cushing Syndrome
Case Report

March 25, 2025

A 72-year-old man with no prior psychiatric history was diagnosed with new-onset psychosis in the setting of hypercortisolism.
,
PCC
Thought Broadcasting and Cultural Beliefs
Case Report

March 18, 2025

A 42-year-old woman attributed her thought broadcasting to the possession of a Ruhani, a type of jinn believed to have the power to influence human thoughts and behaviors.
PCC
Biofeedback for Functional Vomiting Management
Case Report

March 11, 2025

The authors describe 2 patients who responded to biofeedback-based behavioral interventions for functional vomiting.
, , , et al
PCC
A Tale of 2 Lithium Toxicities
Case Report

March 11, 2025

The authors report the cases of 2 patients, both with lithium toxicity; however, the clinical manifestations were paradoxical.
, , , et al
PCC
Pediatric Postinfectious Cranial Neuropathy
Case Report

March 6, 2025

A 14-year-old boy developed acute nasal regurgitation and dysphonia following a febrile illness.
,
PCC
Ketamine-Associated Psychosis After Surgery
Case Report

March 4, 2025

The authors present a unique case of extended postoperative psychosis after intraoperative ketamine induction for analgesia.
, ,

Letter to the Editor

PCC
Revisiting Ayahuasca: Vine of the Soul of the Amazon
Letter to the Editor

March 18, 2025

The authors comment on a case report previously published in the PCC describing psychosis and ayahuasca use and discuss the need for further research given its increased usage worldwide.
,
PCC
Cannabis Withdrawal Psychosis
Letter to the Editor

March 13, 2025

Dr Gorelick comments on a case report recently published in the PCC.
PCC
Cannabis Withdrawal Psychosis: Reply to Gorelick
Letter to the Editor

March 13, 2025

The authors reply to a letter to the editor commenting on their case report.
,
PCC
Parenting Young Adults With ADHD
Letter to the Editor

February 13, 2025

The authors explore the role of parental involvement in supporting young adults with ADHD.
, ,
PCC
Letter to the Editor

December 10, 2024

, , , et al
PCC
Is Bariatric Surgery an Antidepressant?
Letter to the Editor

October 29, 2024

The effect of bariatric surgery on mood disorders is uncertain. Read on to find out more.

More Articles from The Primary Care Companion for DNS Disorders

PCC
Exercise and Fibromyalgia Pain
Systematic Review

March 27, 2025

Adjunctive exercise therapies can be potentially beneficial in improving quality of life through reduction in pain catastrophizing.
, , , et al
PCC
Substance Use in Pregnant and Postpartum Women
Brief Report

March 6, 2025

This study calculated the prevalence of substance use disorder diagnosis among pregnant and postpartum visits in 2020 using inpatient and ED data from the National Hospital Care Survey.
, , , et al
PCC
Challenges in Adult Patients With ARFID
Case Report

March 4, 2025

This case report highlights the need for individualized treatment protocols for adult patients with avoidant-restrictive food intake disorder
, , , et al
PCC
Insulinoma-Induced Mania
Case Report

February 18, 2025

This case highlights the importance of recognizing triggers of mania in patients with hypoglycemic risk factors and comorbid bipolar I disorder.
, ,
PCC
Correction

February 13, 2025

PCC
Reversible Cerebral Vasoconstriction Syndrome in a Young Male With Marijuana Use
Case Report

February 11, 2025

A 17-year-old male presented to the ED with a 2-day history of recurrent thunderclap headache, nausea, vomiting, dizziness, and blurry vision. Read on to find out more about this…
, ,
PCC
Hypnotic Suggestion in Ketamine-Assisted Psychotherapy
Case Report

February 6, 2025

Ketamine combined with an indirect, hypnotic-like suggestion at a key moment prompted important insights and behavior changes that contributed to a patient’s recovery.
PCC
Irritability and Geriatric Depression
Original Research

January 30, 2025

The objective of this study was to determine the frequency of irritability in a sample of geriatric individuals and its clinical relevance in the detection of depression.
, , , et al
PCC
Triiodothyronine Augmentation for TRD
Case Report

January 30, 2025

A middle-aged woman with treatment-resistant depression and atypical features, who had failed several therapeutic trials, safely responded to T3 augmentation.
, , , et al
PCC
COVID’s Mental Health Impact on Primary Care Health Workers
Original Research

January 28, 2025

This study assessed the prevalence of anxiety, depression, insomnia, and perceived stress, as well as the factors that mediate stress with depression and anxiety, among rural health care workers.
, , , et al
PCC
Cannabis Withdrawal–Induced Psychosis
Case Report

January 23, 2025

A 36-year-old man presented with complaints of suspiciousness, irritability, and reduced sleep for more than 2 months, which began within 3 days of stopping heavy marijuana use.
,
PCC
Impact of Lemborexant on Daytime Functioning
Original Research

January 16, 2025

Improved insomnia symptoms with lemborexant treatment may translate into improved daytime functioning.
, , , et al

Watch the New PsychCase360

Explore two real-world schizophrenia cases

Subscribe to read
more articles

Subscribe