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Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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PCC
Irritability and Geriatric Depression
Original Research

January 30, 2025

The objective of this study was to determine the frequency of irritability in a sample of geriatric individuals and its clinical relevance in the detection of depression.
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PCC
Triiodothyronine Augmentation for TRD
Case Report

January 30, 2025

A middle-aged woman with treatment-resistant depression and atypical features, who had failed several therapeutic trials, safely responded to T3 augmentation.
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PCC
COVID’s Mental Health Impact on Primary Care Health Workers
Original Research

January 28, 2025

This study assessed the prevalence of anxiety, depression, insomnia, and perceived stress, as well as the factors that mediate stress with depression and anxiety, among rural health care workers.
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PCC
Cannabis Withdrawal–Induced Psychosis
Case Report

January 23, 2025

A 36-year-old man presented with complaints of suspiciousness, irritability, and reduced sleep for more than 2 months, which began within 3 days of stopping heavy marijuana use.
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PCC
Management of Insomnia in the General Hospital
Rounds in the General Hospital

January 21, 2025

Although the etiology of insomnia is often multi-factorial, both nonpharmacologic and various pharmacologic approaches can provide rapid relief; unfortunately, each is associated with drug-drug interactions and potentially problematic side…
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PCC
Impact of Lemborexant on Daytime Functioning
Original Research

January 16, 2025

Improved insomnia symptoms with lemborexant treatment may translate into improved daytime functioning.
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Vol 26 • 2024 • Number 6

Read the Current Issue

Narrative Review

Dextromethorphan-Quinidine for Agitation in Dementia

Original Research

Psychiatric Comorbidities in Adolescents With Polycystic Ovary Syndrome

Original Research

Intervention to Enhance Mental Health Competency

Original Research

Evolution of Treatment Modalities for PTSD

Rounds in the General Hospital

Etiology, Prevention, and Management of TD

Rounds in the General Hospital

Comorbid Bipolar Disorder and PTSD
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Rounds in the General Hospital Rounds from Banner Alzheimer's Institute

Original Research

PCC
Suicide-Specific Cognitions in US Military Veterans
Original Research

January 14, 2025

This study examined data from a large, nationally representative sample of US veterans to determine the prevalence and correlates of high chronic suicide risk.
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PCC
Psychological Resilience of Mental Health Workers During the Russia-Ukraine War
Original Research

October 22, 2024

Interventions that bolster social connectedness, meaning in life, and optimism may help promote psychological resilience among mental health workers exposed to ongoing war-related and work-related stressors.
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PCC
Relationship Between Social Isolation and Substance Abuse
Original Research

September 24, 2024

This study highlights the connection between social isolation and substance use disorder, emphasizing the need to address social isolation as a public health issue.
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Review Articles

PCC
Improving Collaboration Between Neuropsychology and Primary Care
Narrative Review

October 31, 2024

Collaboration between neuropsychologists and physicians significantly improves patient care by enhancing diagnostic precision and treatment planning. Read on to find out more.
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PCC
Understanding the Child and Adolescent Mental Health Crisis
Narrative Review

October 24, 2024

The authors delve into current mental health challenges facing children and youth, examining perspectives from both pre-pandemic and pandemic periods.
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PCC
Management of Sleep Disturbances in Veterans Following Mild TBI
Narrative Review

September 12, 2024

The authors developed an evidence- and consensus-based clinical recommendation regarding primary care management of insufficient and disturbed sleep associated with concussion/mild traumatic brain injury in service members and veterans.
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PCC
Management of ADHD in Adolescents and Young Adults
Narrative Review

August 6, 2024

Drawing on their clinical experiences of implementing evidence-based guidelines and feedback from patients, the authors describe innovative strategies and solutions for improving the management of ADHD in adolescents and…
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PCC
Tech Gaming Designs, Neurodevelopmental Vulnerabilities, and Internet Gaming Disorder Risk
Narrative Review

July 23, 2024

The authors review the relevant research in the field of internet gaming disorder and provide an approach to identification and management.
PCC
Alternative Treatment for Agitation in Schizophrenia and Bipolar Disorder
Narrative Review

January 30, 2024

While oral and intramuscular formulations of pharmacologic agents continue to be commonly used to treat acute agitation, novel agents with alternative routes of delivery are becoming available.

Rounds in the General Hospital

PCC
Focal Impaired Awareness Seizures: Evaluation and Management
Rounds in the General Hospital

January 3, 2025

Focal impaired awareness seizures can look like other psychiatric, neurological, and medical presentations, and due to the changes in affect, behavior, and cognition, are often misdiagnosed as a primary…
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PCC
Treatment of Pain in the Context of Alcohol and Substance Use Disorders
Rounds in the General Hospital

October 17, 2024

When prescribing opioids for pain, prescription monitoring programs should be checked, regular urine toxicology screening should be conducted, and patients with an opioid use disorder should receive FDA-approved medication…
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PCC
Talking to Your Patients About Psychedelics
Rounds in the General Hospital

October 15, 2024

Given the precipitous increase in both scientific publications and public interest in psychedelics, clinicians should learn more about how they work, what they might work for, and what their…
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PCC
Clozapine: Its Use and Monitoring
Rounds in the General Hospital

July 30, 2024

The authors provide the latest information on clozapine use, including when your patients should receive or avoid taking it, what laboratory tests are required before and during administration, and…
PCC
Pharmacologic Management of TBI
Rounds in the General Hospital

July 16, 2024

Cognitive complaints, including difficulties with attention, concentration, and memory, are common in patients post-TBI; however, many medications have been studied in the treatment of cognition after TBI. Read on…
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PCC
Evaluation and Management of Treatment-Resistant Schizophrenia
Rounds in the General Hospital

July 2, 2024

If you have ever been uncertain about how to evaluate patients with a chronic psychotic illness or struggled over how best to manage treatment-resistant schizophrenia, then this case vignette…
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Case Reports

PCC
Catatonia Associated With Post-Acute COVID-19 in a Young Child
Case Report

January 9, 2025

A 4-year-old girl with high-functioning autism spectrum disorder experienced catatonia associated with the post-acute phase of SARS-CoV-2 infection.
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PCC
Sodium Valproate–Associated Psoriasis
Case Report

January 9, 2025

The authors present a rare case of exacerbation of psoriasiform eruptions in a patient who was prescribed sodium valproate for seizures.
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PCC
Treating Trichotillomania Via Tele-Based Habit Reversal Therapy
Case Report

January 7, 2025

The authors present a case of trichotillomania in a patient who was managed via telepsychiatry-based habit reversal therapy during the COVID-19 pandemic.
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PCC
Broad Differential Diagnoses in a Case of Catatonia
Case Report

January 3, 2025

This case presents a complex clinical scenario in which no single diagnosis fully accounted for the presenting symptoms.
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PCC
Antipsychotic-Induced Lingual Dystonia With Bradycardia
Case Report

December 26, 2024

The authors present a rare case of antipsychotic-induced lingual dystonia that led to hemodynamic changes in a 15-year-old boy.
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PCC
Cyberbullying and Adolescent Mental Health
Case Report

December 26, 2024

Two patients admitted to an inpatient psychiatric unit for suicidality cited interactions with users on the messaging app Discord as a significant stressor contributing to their presentation.
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Letter to the Editor

PCC
Letter to the Editor

December 10, 2024

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PCC
Is Bariatric Surgery an Antidepressant?
Letter to the Editor

October 29, 2024

The effect of bariatric surgery on mood disorders is uncertain. Read on to find out more.
PCC
Harm Reduction in Adolescent Inhalant Use
Letter to the Editor

October 15, 2024

The authors discuss harm reduction efforts targeting inhalant use in the adolescent population.
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PCC
Empathy in AI: Insights from Psychodermatology
Letter to the Editor

October 10, 2024

The authors assessed which AI modality has the most potential to help a patient with delusional parasitosis based on the Empathy Scale for Human–Computer Communication score.
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PCC
Smartphone Applications: Therapy at Your Fingertips
Letter to the Editor

August 20, 2024

Dr Modesto-Lowe and colleagues discuss the advancements in smartphone applications for psychiatry, as well as some of the risks.
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PCC
Zeroing in on Xylazine
Letter to the Editor

August 15, 2024

Dr Kaur and colleagues discuss the need to raise awareness among US public and health care professionals about xylazine due to its infiltration into the illicit drug supply.
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More Articles from The Primary Care Companion for DNS Disorders

PCC
Alzheimer’s Dementia Confirmed by FDG-PET After Negative Neuropsychological Tests
Case Series

December 17, 2024

This case series presents several patients who underwent formal neuropsychological testing that did not diagnose dementia, but whose clinical course and neuroimaging findings were consistent with the diagnosis.
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PCC
Cyproheptadine and Dexamethasone Dependence
Case Series

December 10, 2024

Three cases of cyproheptadine and dexamethasone dependence are presented, with individuals misusing the drugs for rapid weight and muscle gain.
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PCC
Unexpected Hypersensitivity to Bupropion
Case Report

December 5, 2024

A 33-year-old man with a history of depression presented to the emergency department with a rash 3 weeks after starting bupropion.
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PCC
Pindolol for Treatment-Refractory Panic Disorder
Case Report

November 28, 2024

A patient with treatment-resistant panic disorder experienced a significant reduction in the frequency and severity of his attacks after pindolol treatment.
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PCC
Recurrent Catatonia Following Hypothyroidism
Case Report

November 26, 2024

The authors present the case of a 41-year-old woman with schizophrenia, in whom hypothyroidism and recurrent catatonia appear to be linked.
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PCC
Panic Attacks in COVID-19
Case Report

November 21, 2024

This case describes panic attacks that occurred repeatedly as part of the constellation of presenting symptomatology during 2 separate COVID-19 infections.
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PCC
Eating Disorders and Alcohol Misuse
Case Report

November 14, 2024

This report highlights associations between anorexia nervosa and alcohol use disorder, emphasizing biological and psychological aspects of both conditions.
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PCC
Cisplatin-Etoposide–Induced Hyperammonemic Encephalopathy
Case Report

November 12, 2024

A 68-year-old cancer patient experienced delirium during the third cycle of treatment with cisplatin-etoposide.
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PCC
Ototoxicity Associated With Mirtazapine
Case Report

November 7, 2024

A 57-year-old woman experienced hearing loss, tinnitus, and musical hallucinations following several months of mirtazapine use.
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PCC
Misdiagnosis of Uremia-Induced Unilateral Visual Hallucination
Case Report

November 5, 2024

A male patient in his late 40s with type 1 diabetes and chronic stage 3 kidney disease presented with suicidal ideation and persistent unilateral visual hallucinations in his right…
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PCC
Complex Diagnosis of Psychogenic Nonepileptic Seizures
Case Report

October 31, 2024

Diagnosis and treatment of PNES presents a multifaceted challenge. An interdisciplinary approach involving neurology and psychiatry allows for a comprehensive evaluation and tailored therapeutic interventions.
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PCC
Correction

October 31, 2024

Celebrating
85 Years

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