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Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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PCC
Neuropsychiatric Presentation of Vitamin B12 Deficiency
Case Report

April 24, 2025

This case describes a 59-year-old woman with borderline B12 deficiency presenting with only neuropsychiatric symptoms
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PCC
Shock Anxiety After Electrical Storm Treated With CBT
Case Report

April 24, 2025

A patient with arrhythmogenic right ventricular dysplasia/cardiomyopathy, who had recently experienced electrical storm from her implantable cardioverter-defibrillator, developed shock anxiety with phobic avoidance.
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PCC
Secondary Delusional Infestation in a Male with a History of Polysubstance Use
Case Report

April 22, 2025

A 20-year-old man with a history of polysubstance use presented to the ED with a severe pruritic lesion in the left scapular region. Over the past 22 days, he…
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PCC
What Internists and Neurologists Know and Think About Catatonia
Original Research

April 17, 2025

The authors designed and conducted a survey-based study to raise catatonia awareness among internists and neurologists and to inform future educational campaigns.
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PCC
Psychological Morbidities in Hospital Staff During Nipah Virus
Original Research

April 15, 2025

The authors evaluated the prevalence of depression and anxiety among health care workers in a tertiary care hospital during a period of heightened concern due to Nipah virus exposure.
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PCC
Oxcarbazepine/Aripiprazole Interaction and Bipolar Relapse
Case Report

April 10, 2025

This case highlights the interaction between aripiprazole and oxcarbazepine, resulting in subtherapeutic levels of aripiprazole and recurrence of manic symptoms in a patient with bipolar I disorder.
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Vol 27 • 2025 • Number 1

Read the Current Issue

Original Research

Suicide-Specific Cognitions in US Military Veterans

Original Research

Irritability and Geriatric Depression

Rounds in the General Hospital

Prolonged Grief: Etiology and Management

Original Research

Impact of Lemborexant on Daytime Functioning

Rounds in the General Hospital

Management of Insomnia in the General Hospital

Case Report

Hypnotic Suggestion in Ketamine-Assisted Psychotherapy
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Rounds in the General Hospital Rounds from Banner Alzheimer's Institute

Original Research

PCC
Association of Pregnancy-Related Anxiety With Perceived Social Support: An Observational Study Among Third-Trimester Antenatal Women
Original Research

March 20, 2025

Late-pregnancy anxiety was linked to perceived social support, and specific pregnancy-related anxiety themes, such as concerns about giving birth, the child’s health, one’s own appearance, correlated with distinct perceived…
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PCC
Sleepiness in Colombian Medical Students
Original Research

February 18, 2025

This study investigated the prevalence of sleepiness and associated variables among medical students at a university in Santa Marta, Colombia.
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PCC
Medical Education and the COVID-19 Pandemic
Original Research

February 11, 2025

The pandemic disrupted traditional undergraduate medical education and required adaptations to the clerkship curriculum, such as integration of virtual patient care and telehealth services, to provide meaningful learning experiences.
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Review Articles

PCC
Quality Indicators in Community Mental Health Services: A Scoping Review
Review Article

April 8, 2025

Engaging communities in mental health initiatives can improve understanding and support for individuals with mental health disorders and improve quality of the service.
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PCC
Dextromethorphan-Quinidine for Agitation in Dementia
Narrative Review

November 14, 2024

The authors provide an updated summary of the literature on dextromethorphan-quinidine for the treatment of agitation in patients with dementia.
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PCC
Improving Collaboration Between Neuropsychology and Primary Care
Narrative Review

October 31, 2024

Collaboration between neuropsychologists and physicians significantly improves patient care by enhancing diagnostic precision and treatment planning. Read on to find out more.
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PCC
Understanding the Child and Adolescent Mental Health Crisis
Narrative Review

October 24, 2024

The authors delve into current mental health challenges facing children and youth, examining perspectives from both pre-pandemic and pandemic periods.
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PCC
Management of Sleep Disturbances in Veterans Following Mild TBI
Narrative Review

September 12, 2024

The authors developed an evidence- and consensus-based clinical recommendation regarding primary care management of insufficient and disturbed sleep associated with concussion/mild traumatic brain injury in service members and veterans.
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PCC
Management of ADHD in Adolescents and Young Adults
Narrative Review

August 6, 2024

Drawing on their clinical experiences of implementing evidence-based guidelines and feedback from patients, the authors describe innovative strategies and solutions for improving the management of ADHD in adolescents and…
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Rounds in the General Hospital

PCC
Managing Anxiety, Agitation, and Pain in Critically Ill Patients
Rounds in the General Hospital

April 1, 2025

Pain, fear, anxiety, sleep disturbances, and agitation are common symptoms among critically ill patients, causing distress, interfering with medical care, and contributing to morbidity post discharge.
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PCC
Wishing That Your Patient Would Die: Reasons and Reactions
Rounds in the General Hospital

February 25, 2025

The authors explore the complexity, intensity, and critical decision-making faced by health care staff while caring for chronically and critically ill patients, especially in the context of medical futility.
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PCC
Psychosis-Related PTSD
Rounds in the General Hospital

February 6, 2025

Frightening psychotic experiences might serve as traumatic events and precipitate development of PTSD, and the first step to successful management is ensuring a proper assessment.
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PCC
Focal Impaired Awareness Seizures: Evaluation and Management
Rounds in the General Hospital

January 3, 2025

Focal impaired awareness seizures can look like other psychiatric, neurological, and medical presentations, and due to the changes in affect, behavior, and cognition, are often misdiagnosed as a primary…
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PCC
Comorbid Bipolar Disorder and PTSD
Rounds in the General Hospital

December 24, 2024

Bipolar disorder and PTSD are highly comorbid conditions, and pharmacologic management poses unique challenges, as side effects of the commonly used medications for one disorder can worsen the symptoms…
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PCC
Etiology, Prevention, and Management of TD
Rounds in the General Hospital

November 19, 2024

It is critical to detect TD early in its course and adjust medications to those that are less likely to cause it. Left untreated, TD is typically irreversible, disfiguring,…
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Case Reports

PCC
Is My Patient Diverting Their Lorazepam?
Case Report

April 3, 2025

Urine drug testing is used to monitor compliance in patients prescribed controlled substances; a negative test can suggest diversion to family or friends or illicit sale of the medication.
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PCC
First-Episode Psychosis and Cushing Syndrome
Case Report

March 25, 2025

A 72-year-old man with no prior psychiatric history was diagnosed with new-onset psychosis in the setting of hypercortisolism.
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PCC
Thought Broadcasting and Cultural Beliefs
Case Report

March 18, 2025

A 42-year-old woman attributed her thought broadcasting to the possession of a Ruhani, a type of jinn believed to have the power to influence human thoughts and behaviors.
PCC
Biofeedback for Functional Vomiting Management
Case Report

March 11, 2025

The authors describe 2 patients who responded to biofeedback-based behavioral interventions for functional vomiting.
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PCC
A Tale of 2 Lithium Toxicities
Case Report

March 11, 2025

The authors report the cases of 2 patients, both with lithium toxicity; however, the clinical manifestations were paradoxical.
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PCC
Pediatric Postinfectious Cranial Neuropathy
Case Report

March 6, 2025

A 14-year-old boy developed acute nasal regurgitation and dysphonia following a febrile illness.
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Letter to the Editor

PCC
Revisiting Ayahuasca: Vine of the Soul of the Amazon
Letter to the Editor

March 18, 2025

The authors comment on a case report previously published in the PCC describing psychosis and ayahuasca use and discuss the need for further research given its increased usage worldwide.
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PCC
Cannabis Withdrawal Psychosis
Letter to the Editor

March 13, 2025

Dr Gorelick comments on a case report recently published in the PCC.
PCC
Cannabis Withdrawal Psychosis: Reply to Gorelick
Letter to the Editor

March 13, 2025

The authors reply to a letter to the editor commenting on their case report.
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PCC
Parenting Young Adults With ADHD
Letter to the Editor

February 13, 2025

The authors explore the role of parental involvement in supporting young adults with ADHD.
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PCC
Letter to the Editor

December 10, 2024

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PCC
Is Bariatric Surgery an Antidepressant?
Letter to the Editor

October 29, 2024

The effect of bariatric surgery on mood disorders is uncertain. Read on to find out more.

More Articles from The Primary Care Companion for DNS Disorders

PCC
Exercise and Fibromyalgia Pain
Systematic Review

March 27, 2025

Adjunctive exercise therapies can be potentially beneficial in improving quality of life through reduction in pain catastrophizing.
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PCC
Substance Use in Pregnant and Postpartum Women
Brief Report

March 6, 2025

This study calculated the prevalence of substance use disorder diagnosis among pregnant and postpartum visits in 2020 using inpatient and ED data from the National Hospital Care Survey.
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PCC
Ketamine-Associated Psychosis After Surgery
Case Report

March 4, 2025

The authors present a unique case of extended postoperative psychosis after intraoperative ketamine induction for analgesia.
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PCC
Challenges in Adult Patients With ARFID
Case Report

March 4, 2025

This case report highlights the need for individualized treatment protocols for adult patients with avoidant-restrictive food intake disorder
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PCC
Thyrotoxic Psychosis in Graves’ Disease
Case Report

February 27, 2025

A patient with a 2-year history of Graves’ disease and nonadherent to anti-thyroid treatment developed mania with psychosis.
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PCC
Factitious Disorder in the Context of Abuse in an Adolescent
Case Report

February 27, 2025

This case illustrates the complexities of diagnosing factitious disorder in adolescents, in which psychosocial factors play a significant role.
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PCC
Frontal Lobe Syndrome Unveils an Unexpected Diagnosis
Case Report

February 20, 2025

A 55-year-old man was admitted to the psychiatric ED due to changes in behavior, posing risk to himself and to others, and refusing medical assistance. A CT scan revealed…
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PCC
Low-Dose Clozapine in Schizophrenia With Aggression
Case Report

February 20, 2025

A patient with schizophrenia with significant aggression achieved remission with a low dose of clozapine started after the first failed antipsychotic trial.
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PCC
Insulinoma-Induced Mania
Case Report

February 18, 2025

This case highlights the importance of recognizing triggers of mania in patients with hypoglycemic risk factors and comorbid bipolar I disorder.
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PCC
Correction

February 13, 2025

PCC
Reversible Cerebral Vasoconstriction Syndrome in a Young Male With Marijuana Use
Case Report

February 11, 2025

A 17-year-old male presented to the ED with a 2-day history of recurrent thunderclap headache, nausea, vomiting, dizziness, and blurry vision. Read on to find out more about this…
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PCC
Triiodothyronine Augmentation for TRD
Case Report

January 30, 2025

A middle-aged woman with treatment-resistant depression and atypical features, who had failed several therapeutic trials, safely responded to T3 augmentation.
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