Letter to the Editor June 15, 2007

Vitamin B12 Deficiency Manifested as Mania: A Case Report

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Prim Care Companion J Clin Psychiatry 2007;9(3):238

Article Abstract

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Sir: Multiple psychiatric symptoms may precede perniciousanemia. Only 1 case of full manic syndrome secondary to B12deficiency has been reported.1

 

Case report. Ms. A was a 35-year-old woman with no personalor family history of psychiatric disorders, who was admittedto the hospital in February of 2005 with a 3-weekhistory of episodes of manic symptoms of several hours’ duration,including grandiosity, hyperactivity, sexual indiscretion,hyperphagia, irritable mood, reckless behavior, flight of ideas,and overbearing manner.