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PCC
Case Report

March 3, 2026

This case highlights the need for enhanced recognition of misophonia, integrated care pathways, and improved mental health infrastructure in low- and middle-income countries.
PCC
Depression and CVD in Aging Populations
Original Research

March 3, 2026

Even infrequent depressive symptoms are associated with elevated cardiovascular risk in adults aged 50 and older, and those who report both depressive symptoms and either obesity or current smoking…
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PCC
Intranasal Tapentadol Dependence
Case Report

February 26, 2026

The authors present 2 cases of intranasal tapentadol dependence marked by rapid tolerance and significant physical and psychological issues.
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PCC
Practice Relevance as the North Star: A Message From the Editor
Editorial

February 26, 2026

Dr Culpepper, Editor in Chief, outlines manuscript selection criteria for the PCC, prioritizing clinical relevance to primary care and frontline psychiatric settings, and thanks peer reviewers for their service.
PCC
Understanding the Impact of Moral Injury
Rounds in the General Hospital

February 26, 2026

Healing of moral injuries requires truth-telling, communal recognition, and moral repair—not just medication or cognitive restructuring.
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PCC
CTRA, Stress, and Yoga
Letter to the Editor

February 24, 2026

The authors examine the historical context of stress, the neurobiological mechanisms of conserved transcriptional response to adversity and stress, and how yoga practices counteract its effects.
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Figure—Magazine cover highlights articles on suicide attempts, family support, impulsivity, grief, and bipolar disorder care.

Vol 28 • 2026 • Number 1

Read the Current Issue

Original Research

Suicidal Mental Imagery in Suicide Attempters

Original Research

Family Support for Patients With Substance Use Disorders

Rounds in the General Hospital

Diagnosing and Treating Impulsivity

Rounds in the General Hospital

Managing Grief and Bereavement

Brief Report

Measurement-Based Care for Bipolar Disorder

Rounds in the General Hospital

Treatment and Referral for AUD in Primary Care
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Rounds in the General Hospital Rounds from Banner Alzheimer's Institute

Original Research

PCC
Validation of the APREMDI Scale for Brazilian Portuguese
Original Research

February 19, 2026

The APREMDI scale allows clinicians to quantitatively assess patients’ perceptions of respect and dignity during hospitalization, helping to identify subtle dignity violations that may compromise recovery and satisfaction.
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PCC
Daylight Duration and rTMS Outcomes in Treatment-Resistant Depression
Original Research

February 3, 2026

The authors examine the possible impact of daylight duration during the course of repetitive transcranial magnetic stimulation on its efficacy in patients with treatment-resistant depression.
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PCC
Impact of Patient Suicide on Mental Health Professionals
Original Research

November 20, 2025

Patient suicide can cause lasting emotional and professional distress in mental health professionals due to their unique relationship with the patient.
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Review Articles

PCC
Gender-Affirming Surgery, Gender Dysphoria, and QOL
Review Article

November 11, 2025

Those who receive gender dysphoria treatment at a younger age may experience lower rates of suicidal ideation, underscoring potential mental health benefits of timely intervention.
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PCC
Improving Community Mental Health Care
Narrative Review

October 9, 2025

This review highlights critical areas for enhancing the quality and sustainability of community mental health services.
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PCC
Precision Psychiatry for Depression Treatment
Narrative Review

September 9, 2025

Novel precision medicine tools in depression aim to identify the optimal treatment for each patient and have the potential to significantly improve depression management by guiding treatment selection for…
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PCC
Incretin Therapies: A New Tool to Combat Metabolic Consequences of Antipsychotic Use
Narrative Review

September 4, 2025

Incretin therapies have emerged as a promising treatment option with potential benefits for mitigating cardiometabolic side effects associated with antipsychotics; however, clinical trials have often excluded psychiatric populations.
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PCC
Climate Change and Mental Health
Review Article

July 24, 2025

This scoping review highlights the significant impact of climate change on mental health in India, particularly among individuals from lower socioeconomic backgrounds in rural areas.
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PCC
Efficacy of GLP-1 Agonists in Mental Disorders
Review Article

June 10, 2025

Current evidence underscores the potential of GLP-1 receptor agonists as a novel therapeutic approach for certain psychiatric disorders, particularly AUDs, depression, and autism-related food behaviors.
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Rounds in the General Hospital

PCC
Preventing Physician Burnout
Rounds in the General Hospital

February 10, 2026

The authors clarify misconceptions about burnout and depression and identify best practices and approaches for burnout at the individual and institutional level.
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PCC
Diagnosis and Management of Rage
Rounds in the General Hospital

December 23, 2025

This article offers a practical framework for distinguishing rage from irritability and impulsivity, identifying underlying neuropsychiatric drivers, and guiding evidence-based management across conditions including PTSD, TBI, and mood disorders.
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PCC
Facilitating Academic Success for Clinicians
Rounds in the General Hospital

December 16, 2025

Many clinicians, experience “imposter syndrome,” which can foster the false belief that they are unqualified for promotion.
, , , et al
PCC
Using Digital Technologies to Avoid Doctor’s Orders
Rounds in the General Hospital

December 2, 2025

The availability of portable technologies and application-based services can complicate caretaking in the hospital setting, as patients can circumvent medical recommendations.
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PCC
Sequelae of Toxic Exposures in Veterans
Rounds in the General Hospital

November 25, 2025

A 45-year-old veteran has ongoing symptoms likely related to past exposure to burn pits, dust storms, airborne industrial pollutants, and head trauma from hard parachute landings.
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PCC
Primary Care and Mental Health Collaboration
Rounds in the General Hospital

November 13, 2025

Since PCPs are often the first health care professionals to see patients with symptoms of a mental health disorder, they play a vital role in the identification, management, and…
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Case Reports

PCC
Calcineurin Inhibitor–Induced Psychosis
Case Report

February 17, 2026

The authors report a case of delayed and recurrent calcineurin inhibitor–induced psychosis with both tacrolimus and cyclosporine, highlighting the need to better understand host vulnerability and risk stratification.
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PCC
Arm EMG and Detection of REM Sleep Without Atonia
Case Report

February 17, 2026

This case highlights the importance of utilizing arm EMG to accurately detect REM sleep without atonia, as REM sleep behavior disorder often precedes the development of α-synucleinopathies, such as…
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PCC
Long-Term High-Intensity Drinking
Case Report

February 12, 2026

This case underscores the need to recognize episodic high-intensity alcohol use as a clinically relevant presentation that carries medical and social risks despite the absence of daily drinking.
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PCC
Periodic Catatonia in an Adult With Autism
Case Report

February 3, 2026

The authors report a case of periodic catatonia in a 30-year-old man with autism spectrum disorder, with no other identifiable psychiatric or neurological comorbidities, that responded to lithium prophylaxis.
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PCC
When the Labs Don’t Add Up: Factitious Disorder and Successful Treatment
Case Report

January 27, 2026

This case of a 37-year-old woman, who presented to the ED with recurrent syncope and acute kidney injury, demonstrates successful long-term treatment of factitious disorder, highlighting the complexities of…
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PCC
High-dose Veterinary AMP Dependence
Case Report

January 27, 2026

A 41-year-old man self-administered mega-doses of veterinary adenosine monophosphate over an extended period and experienced intense withdrawal and psychological symptoms after discontinuation.
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Letter to the Editor

PCC
Psychotropic-Related Aspiration Hazards
Letter to the Editor

February 10, 2026

The authors discuss the importance of a choking prevention policy to identify those at heightened risk for choking hazards, particularly psychiatric patients.
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PCC
Lysing Catatonia to Uncover the Driving Illness
Letter to the Editor

January 29, 2026

The author comments on a recent PCC article and offers an alternative diagnostic perspective.
PCC
Clarifying the Delirium in Bell’s Mania: Reply to Intrator
Letter to the Editor

January 29, 2026

The authors respond to a letter to the editor commenting on their article.
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PCC
Kratom-Induced Psychosis
Letter to the Editor

January 8, 2026

The author comments on the complexity of substance-induced presentations, particularly those related to newly available psychoactive substances such as kratom.
PCC
Semaglutide for Alcohol Use Disorder
Letter to the Editor

January 1, 2026

The authors explore potential mechanisms underlying the relationship between GLP-1 agonists and AUD as well as studies evaluating semaglutide for AUD.
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PCC
Psychosis Screening in Genetic Disorders
Letter to the Editor

December 4, 2025

The author discusses routine monitoring for the development of psychotic symptoms among individuals with rare genetic disorders that confer risk for psychosis.

More Articles from The Primary Care Companion for DNS Disorders

PCC
Basal Ganglia Stroke With Lower Motor Neuron Features
Case Report

January 22, 2026

A 60-year-old man exhibited left-sided toe walking and right-sided weakness despite previous history of left sided basal ganglia stroke, challenging the notion that adult toe walking is a hallmark…
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PCC
Benign Ethnic Neutropenia and Clozapine
Case Report

January 22, 2026

This case highlights the importance of recognizing benign ethnic neutropenia to prevent unnecessary clozapine discontinuation.
, , , et al
PCC
Depression Remission in Parkinson Disease With iTBS
Case Report

January 20, 2026

Two cases demonstrate the potential for intermittent theta burst transcranial magnetic stimulation to rapidly reverse treatment-resistant depression in patients with Parkinson disease.
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PCC
Lithium-Induced Rash: Unveiling the Dermatological Dilemma
Case Report

January 20, 2026

A 32-year-old woman recently diagnosed with bipolar affective disorder developed lithium-induced rash that did not recur on rechallenge.
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PCC
Skin Picking in Profound Intellectual Disability
Case Report

January 15, 2026

A 39-year-old woman with profound intellectual disability and delayed developmental milestones presented with late-onset severe dermatillomania.
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PCC
LSD-Induced Catatonia in an Adolescent
Case Report

January 13, 2026

A 16-year-old boy experienced catatonia associated with lysergic acid diethylamide use.
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PCC
Cotard Syndrome in Schizophrenia
Case Report

January 8, 2026

A 42-year-old woman with schizophrenia and multiple prior hospitalizations presented with worsening psychosis and physical aggression toward her mother.
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PCC
Transient Loss of Consciousness in an Adolescent with Pathological Intoxication
Case Report

January 1, 2026

This case of atypical symptoms in a 15-year-old boy underscores the need to differentiate pathological intoxication from seizures and psychiatric conditions, emphasizing alcohol abstinence.
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PCC
Machine Madness: A Case of Artificial Intelligence Psychosis
Case Report

December 30, 2025

A 41-year-old man with a history of substance-induced psychosis, developed symptoms of psychosis related to frequent occupational use of AI.
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PCC
A Case of Kratom Withdrawal
Case Report

December 25, 2025

A 29-year-old man experienced kratom withdrawal that necessitated intensive care management and resulted in subsequent cardiac arrest.
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PCC
Clozapine-Induced Corrected QT-Interval Prolongation and Relationship With Serum Clozapine Concentration
Case Report

December 18, 2025

The author presents a case of clozapine-induced QTc prolongation and discusses its relationship with serum clozapine concentration
PCC
Balancing Pragmatism and Ethics in Psychiatry
Case Report

December 16, 2025

A psychiatrist strategically used a patient’s internalized fear of extremism to redirect behavior during a manic episode.

Consensus Report on XT Use in Practice

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Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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